Protein Targets


Protein Protein name Organism Symbol Gene UniProt ChEMBL Compounds
5-hydroxytryptamine receptor 1A Homo sapiens; Human 5HT1A_HUMAN HTR1A P08908 CHEMBL214 9422 / 10016
5-hydroxytryptamine receptor 1B Homo sapiens; Human 5HT1B_HUMAN HTR1B P28222 CHEMBL1898 2475 / 2634
5-hydroxytryptamine receptor 1D Homo sapiens; Human 5HT1D_HUMAN HTR1D P28221 CHEMBL1983 2655 / 2754
5-hydroxytryptamine receptor 1E Homo sapiens; Human 5HT1E_HUMAN HTR1E P28566 CHEMBL2182 565 / 597
5-hydroxytryptamine receptor 1F Homo sapiens; Human 5HT1F_HUMAN HTR1F P30939 CHEMBL1805 212 / 222
5-hydroxytryptamine receptor 2A Homo sapiens; Human 5HT2A_HUMAN HTR2A P28223 CHEMBL224 8589 / 10505
5-hydroxytryptamine receptor 2B Homo sapiens; Human 5HT2B_HUMAN HTR2B P41595 CHEMBL1833 4230 / 5981
5-hydroxytryptamine receptor 2C Homo sapiens; Human 5HT2C_HUMAN HTR2C P28335 CHEMBL225 7347 / 9196
5-hydroxytryptamine receptor 4 Homo sapiens; Human 5HT4R_HUMAN HTR4 Q13639 CHEMBL1875 1760 / 1877
5-hydroxytryptamine receptor 5A Homo sapiens; Human 5HT5A_HUMAN HTR5A P47898 CHEMBL3426 1119 / 1184
5-hydroxytryptamine receptor 6 Homo sapiens; Human 5HT6R_HUMAN HTR6 P50406 CHEMBL3371 6970 / 8783
5-hydroxytryptamine receptor 7 Homo sapiens; Human 5HT7R_HUMAN HTR7 P34969 CHEMBL3155 4455 / 4622
adenosine A1 receptor Homo sapiens; Human AA1R_HUMAN ADORA1 P30542 CHEMBL226 12364 / 14663
adenosine A2a receptor Homo sapiens; Human AA2AR_HUMAN ADORA2A P29274 CHEMBL251 11667 / 13796
adenosine A2b receptor Homo sapiens; Human AA2BR_HUMAN ADORA2B P29275 CHEMBL255 6617 / 6983
adenosine A3 receptor Homo sapiens; Human AA3R_HUMAN ADORA3 P0DMS8 CHEMBL256 10578 / 12770
cholinergic receptor muscarinic 1 Homo sapiens; Human ACM1_HUMAN CHRM1 P11229 CHEMBL216 6980 / 8900
cholinergic receptor muscarinic 2 Homo sapiens; Human ACM2_HUMAN CHRM2 P08172 CHEMBL211 4670 / 6568
cholinergic receptor muscarinic 3 Homo sapiens; Human ACM3_HUMAN CHRM3 P20309 CHEMBL245 4350 / 6109
cholinergic receptor muscarinic 4 Homo sapiens; Human ACM4_HUMAN CHRM4 P08173 CHEMBL1821 3558 / 5422
cholinergic receptor muscarinic 5 Homo sapiens; Human ACM5_HUMAN CHRM5 P08912 CHEMBL2035 2416 / 4200
melanocortin 2 receptor Homo sapiens; Human ACTHR_HUMAN MC2R Q01718 CHEMBL1965 33 / 35
adrenoceptor alpha 1D Homo sapiens; Human ADA1D_HUMAN ADRA1D P25100 CHEMBL223 2404 / 4100
adrenoceptor alpha 2A Homo sapiens; Human ADA2A_HUMAN ADRA2A P08913 CHEMBL1867 2341 / 3984
adrenoceptor alpha 2B Homo sapiens; Human ADA2B_HUMAN ADRA2B P18089 CHEMBL1942 1450 / 3084
adrenoceptor alpha 2C Homo sapiens; Human ADA2C_HUMAN ADRA2C P18825 CHEMBL1916 1786 / 3449
adrenoceptor beta 1 Homo sapiens; Human ADRB1_HUMAN ADRB1 P08588 CHEMBL213 3273 / 5152
adrenoceptor beta 2 Homo sapiens; Human ADRB2_HUMAN ADRB2 P07550 CHEMBL210 6371 / 8365
adrenoceptor beta 3 Homo sapiens; Human ADRB3_HUMAN ADRB3 P13945 CHEMBL246 3706 / 5472
angiotensin II receptor type 2 Homo sapiens; Human AGTR2_HUMAN AGTR2 P50052 CHEMBL4607 651 / 2421
bradykinin receptor B2 Homo sapiens; Human BKRB2_HUMAN BDKRB2 P30411 CHEMBL3157 1048 / 2828
calcitonin receptor Homo sapiens; Human CALCR_HUMAN CALCR P30988 CHEMBL1832 467 / 2215
cholecystokinin A receptor Homo sapiens; Human CCKAR_HUMAN CCKAR P32238 CHEMBL1901 1406 / 3226
C-C motif chemokine receptor 1 Homo sapiens; Human CCR1_HUMAN CCR1 P32246 CHEMBL2413 1646 / 1704
C-C motif chemokine receptor 2 Homo sapiens; Human CCR2_HUMAN CCR2 P41597 CHEMBL4015 3529 / 5515
C-C motif chemokine receptor 4 Homo sapiens; Human CCR4_HUMAN CCR4 P51679 CHEMBL2414 980 / 2812
C-C motif chemokine receptor 5 Homo sapiens; Human CCR5_HUMAN CCR5 P51681 CHEMBL274 3691 / 5541
cysteinyl leukotriene receptor 1 Homo sapiens; Human CLTR1_HUMAN CYSLTR1 Q9Y271 CHEMBL1798 348 / 2083
cannabinoid receptor 1 Homo sapiens; Human CNR1_HUMAN CNR1 P21554 CHEMBL218 14060 / 16708
cannabinoid receptor 2 Homo sapiens; Human CNR2_HUMAN CNR2 P34972 CHEMBL253 14804 / 15481
C-X-C motif chemokine receptor 1 Homo sapiens; Human CXCR1_HUMAN CXCR1 P25024 CHEMBL4029 459 / 2217
C-X-C motif chemokine receptor 2 Homo sapiens; Human CXCR2_HUMAN CXCR2 P25025 CHEMBL2434 1521 / 3279
C-X-C motif chemokine receptor 3 Homo sapiens; Human CXCR3_HUMAN CXCR3 P49682 CHEMBL4441 2267 / 2386
C-X-C motif chemokine receptor 4 Homo sapiens; Human CXCR4_HUMAN CXCR4 P61073 CHEMBL2107 2874 / 3025
dopamine receptor D1 Homo sapiens; Human DRD1_HUMAN DRD1 P21728 CHEMBL2056 4538 / 6427
dopamine receptor D2 Homo sapiens; Human DRD2_HUMAN DRD2 P14416 CHEMBL217 17907 / 20602
dopamine receptor D3 Homo sapiens; Human DRD3_HUMAN DRD3 P35462 CHEMBL234 9435 / 11350
dopamine receptor D4 Homo sapiens; Human DRD4_HUMAN DRD4 P21917 CHEMBL219 4850 / 6919
dopamine receptor D5 Homo sapiens; Human DRD5_HUMAN DRD5 P21918 CHEMBL1850 1083 / 1223
endothelin receptor type A Homo sapiens; Human EDNRA_HUMAN EDNRA P25101 CHEMBL252 2372 / 4149
gamma-aminobutyric acid type B receptor subunit 1 Homo sapiens; Human GABR1_HUMAN GABBR1 Q9UBS5 CHEMBL2064 56 / 57
cholecystokinin B receptor Homo sapiens; Human GASR_HUMAN CCKBR P32239 CHEMBL298 2586 / 2648
glutamate metabotropic receptor 1 Homo sapiens; Human GRM1_HUMAN GRM1 Q13255 CHEMBL3772 2162 / 2235
glutamate metabotropic receptor 2 Homo sapiens; Human GRM2_HUMAN GRM2 Q14416 CHEMBL5137 2959 / 3023
glutamate metabotropic receptor 3 Homo sapiens; Human GRM3_HUMAN GRM3 Q14832 CHEMBL2888 608 / 651
glutamate metabotropic receptor 4 Homo sapiens; Human GRM4_HUMAN GRM4 Q14833 CHEMBL2736 2079 / 2208
glutamate metabotropic receptor 5 Homo sapiens; Human GRM5_HUMAN GRM5 P41594 CHEMBL3227 5553 / 5718
glutamate metabotropic receptor 6 Homo sapiens; Human GRM6_HUMAN GRM6 O15303 CHEMBL4573 343 / 347
glutamate metabotropic receptor 7 Homo sapiens; Human GRM7_HUMAN GRM7 Q14831 CHEMBL3777 254 / 262
glutamate metabotropic receptor 8 Homo sapiens; Human GRM8_HUMAN GRM8 O00222 CHEMBL3228 322 / 337
histamine receptor H1 Homo sapiens; Human HRH1_HUMAN HRH1 P35367 CHEMBL231 3452 / 5410
histamine receptor H2 Homo sapiens; Human HRH2_HUMAN HRH2 P25021 CHEMBL1941 1700 / 3476
histamine receptor H3 Homo sapiens; Human HRH3_HUMAN HRH3 Q9Y5N1 CHEMBL264 7509 / 7713
histamine receptor H4 Homo sapiens; Human HRH4_HUMAN HRH4 Q9H3N8 CHEMBL3759 3548 / 3701
melanocortin 3 receptor Homo sapiens; Human MC3R_HUMAN MC3R P41968 CHEMBL4644 2349 / 4144
melanocortin 4 receptor Homo sapiens; Human MC4R_HUMAN MC4R P32245 CHEMBL259 7103 / 8936
melanocortin 5 receptor Homo sapiens; Human MC5R_HUMAN MC5R P33032 CHEMBL4608 2374 / 4165
melanocortin 1 receptor Homo sapiens; Human MSHR_HUMAN MC1R Q01726 CHEMBL3795 2378 / 2473
tachykinin receptor 1 Homo sapiens; Human NK1R_HUMAN TACR1 P25103 CHEMBL249 4191 / 5999
tachykinin receptor 2 Homo sapiens; Human NK2R_HUMAN TACR2 P21452 CHEMBL2327 1560 / 3250
neuropeptides B and W receptor 1 Homo sapiens; Human NPBW1_HUMAN NPBWR1 P48145 CHEMBL1293293 542 / 550
neuropeptide FF receptor 1 Homo sapiens; Human NPFF1_HUMAN NPFFR1 Q9GZQ6 CHEMBL5951 329 / 349
neuropeptide S receptor 1 Homo sapiens; Human NPSR1_HUMAN NPSR1 Q6W5P4 CHEMBL5162 15764 / 15784
neuropeptide Y receptor Y1 Homo sapiens; Human NPY1R_HUMAN NPY1R P25929 CHEMBL4777 1894 / 3752
neuropeptide Y receptor Y2 Homo sapiens; Human NPY2R_HUMAN NPY2R P49146 CHEMBL4018 1454 / 3262
neuropeptide Y receptor Y4 Homo sapiens; Human NPY4R_HUMAN NPY4R P50391 CHEMBL4877 772 / 824
neuropeptide Y receptor Y5 Homo sapiens; Human NPY5R_HUMAN NPY5R Q15761 CHEMBL4561 1682 / 1788
opioid receptor delta 1 Homo sapiens; Human OPRD_HUMAN OPRD1 P41143 CHEMBL236 10731 / 12871
opioid receptor kappa 1 Homo sapiens; Human OPRK_HUMAN OPRK1 P41145 CHEMBL237 11463 / 13975
opioid receptor mu 1 Homo sapiens; Human OPRM_HUMAN OPRM1 P35372 CHEMBL233 12998 / 15406
opioid related nociceptin receptor 1 Homo sapiens; Human OPRX_HUMAN OPRL1 P41146 CHEMBL2014 3236 / 3473
platelet activating factor receptor Homo sapiens; Human PTAFR_HUMAN PTAFR P25105 CHEMBL250 822 / 2569
trace amine associated receptor 1 Homo sapiens; Human TAAR1_HUMAN TAAR1 Q96RJ0 CHEMBL5857 1333 / 1340
thyroid stimulating hormone receptor Homo sapiens; Human TSHR_HUMAN TSHR P16473 CHEMBL1963 29918 / 29937
arginine vasopressin receptor 1A Homo sapiens; Human V1AR_HUMAN AVPR1A P37288 CHEMBL1889 2156 / 3971
vasoactive intestinal peptide receptor 1 Homo sapiens; Human VIPR1_HUMAN VIPR1 P32241 CHEMBL5144 148 / 1892