Protein Targets - Coronavirus (CoV)


Protein Protein name Organism Symbol Gene UniProt ChEMBL Compounds
Hemagglutinin-esterase Bovine coronavirus; strain Mebus; BCoV; BCV HE_BCV HE P15776
Hemagglutinin-esterase Human coronavirus OC43; HCoV-OC43 HE_HCoV-OC43 HE Q4VID6
Hemagglutinin-esterase Murine coronavirus; strain DVIM; MHV-DVIM; Murine hepatitis virus HE_MHV HE O92367
Replicase polyprotein 1ab Bat coronavirus HKU4; BtCoV; BtCoV/HKU4/2004 MD_HKU4 REP P0C6W3
Replicase polyprotein 1a Middle East respiratory syndrome-related coronavirus; isolate United Kingdom/H123990006/2012; MERS-CoV; Betacoronavirus England 1 MD_MERs 1A K9N638
Methyltransferase Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2 MTASE_SARS2 MTASE
Methyltransferase Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2 MTASE_SARS2 MTASE
Nucleoprotein Human coronavirus NL63; HCoV-NL63 NP_HCoV-NL63 N Q6Q1R8
Nucleoprotein Human coronavirus OC43; HCoV-OC43 NP_HCoV-OC43 N P33469 CHEMBL3232681 4 / 4
Nucleoprotein Severe acute respiratory syndrome coronavirus; SARS-CoV NP_SARS N P59595
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus; SARS-CoV NSP15_SARS REP P0C6X7 CHEMBL5118 357 / 378
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2 NSP15_SARS2 NSP15
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus; SARS-CoV NSP1_SARS REP P0C6X7 CHEMBL5118 357 / 378
Replicase polyprotein 1a Human coronavirus 229E; HCoV-229E NSP3_HCoV-229E 1A P0C6U2
Replicase polyprotein 1ab Murine coronavirus; strain A59; MHV-A59; Murine hepatitis virus NSP3_MHV REP P0C6X9
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2 NSP3_SARS2 NSP3
Replicase polyprotein 1ab Human coronavirus 229E; HCoV-229E NSP9_HCoV-229E REP P0C6X1
Replicase polyprotein 1a Severe acute respiratory syndrome coronavirus; SARS-CoV PLP_SARS 1A P0C6U8 CHEMBL3927 315 / 329
papain-like protease Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2 PLP_SARS2 PLP
Replicase polyprotein 1ab Feline coronavirus; strain FIPV WSU-79/1146; FCoV PR_FCoV REP Q98VG9 CHEMBL4295624 12 / 12
Replicase polyprotein 1a Human coronavirus 229E; HCoV-229E PR_HCoV-229E 1A P0C6U2
Replicase polyprotein 1a Human coronavirus NL63; HCoV-NL63 PR_HCoV-NL63 1A P0C6U6 CHEMBL3232683 18 / 18
Replicase polyprotein 1a Human coronavirus HKU1; isolate N1; HCoV-HKU1 PR_HKU1 1A P0C6U3
Replicase polyprotein 1ab Bat coronavirus HKU4; BtCoV; BtCoV/HKU4/2004 PR_HKU4 REP P0C6W3
3C-like proteinase Middle East respiratory syndrome-related coronavirus; MERS-CoV PR_MERs ORF1A V9TU12
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus; SARS-CoV PR_SARS REP P0C6X7 CHEMBL5118 357 / 378
3C-like protease Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2 PR_SARS2 PR
Replicase polyprotein 1a Porcine transmissible gastroenteritis coronavirus; strain Purdue; TGEV PR_TGEV 1A P0C6V2
RNA-dependent RNA polymerase Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2 RDRP_SARS2 RDRP
Spike glycoprotein Human coronavirus 229E; HCoV-229E SPIKE_HCoV-229E S P15423
Spike glycoprotein Human coronavirus NL63; HCoV-NL63 SPIKE_HCoV-NL63 S Q6Q1S2
Spike glycoprotein Human coronavirus OC43; HCoV-OC43 SPIKE_HCoV-OC43 S Q696P8
Spike glycoprotein Bat coronavirus HKU4; BtCoV; BtCoV/HKU4/2004 SPIKE_HKU4 S A3EX94
Spike glycoprotein Middle East respiratory syndrome-related coronavirus; isolate United Kingdom/H123990006/2012; MERS-CoV; Betacoronavirus England 1 SPIKE_MERs S K9N5Q8
Spike protein Deltacoronavirus PDCoV/USA/Ohio137/2014 SPIKE_PDCoV S A0A075E3D7
Spike glycoprotein Severe acute respiratory syndrome coronavirus; SARS-CoV SPIKE_SARS S P59594
Spike glycoprotein Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2 SPIKE_SARS2 S P0DTC2