Protein Targets - Coronavirus (CoV)

ProteinProtein nameOrganismSymbolGeneUniProtChEMBLCompounds
Hemagglutinin-esterase Bovine coronavirus; strain Mebus; BCoV; BCVHE_BCVHEP15776
Hemagglutinin-esterase Human coronavirus OC43; HCoV-OC43HE_HCoV-OC43HEQ4VID6
Hemagglutinin-esterase Murine coronavirus; strain DVIM; MHV-DVIM; Murine hepatitis virusHE_MHVHEO92367
Replicase polyprotein 1ab Bat coronavirus HKU4; BtCoV; BtCoV/HKU4/2004MD_HKU4REPP0C6W3
Replicase polyprotein 1a Middle East respiratory syndrome-related coronavirus; isolate United Kingdom/H123990006/2012; MERS-CoV; Betacoronavirus England 1MD_MERs1AK9N638
Methyltransferase Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2MTASE_SARS2MTASE
Methyltransferase Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2MTASE_SARS2MTASE
Nucleoprotein Human coronavirus NL63; HCoV-NL63NP_HCoV-NL63NQ6Q1R8
Nucleoprotein Human coronavirus OC43; HCoV-OC43NP_HCoV-OC43NP33469 CHEMBL3232681 4 / 4
Nucleoprotein Severe acute respiratory syndrome coronavirus; SARS-CoVNP_SARSNP59595
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus; SARS-CoVNSP15_SARSREPP0C6X7 CHEMBL5118 357 / 378
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2NSP15_SARS2NSP15
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus; SARS-CoVNSP1_SARSREPP0C6X7 CHEMBL5118 357 / 378
Replicase polyprotein 1a Human coronavirus 229E; HCoV-229ENSP3_HCoV-229E1AP0C6U2
Replicase polyprotein 1ab Murine coronavirus; strain A59; MHV-A59; Murine hepatitis virusNSP3_MHVREPP0C6X9
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2NSP3_SARS2NSP3
Replicase polyprotein 1ab Human coronavirus 229E; HCoV-229ENSP9_HCoV-229EREPP0C6X1
Replicase polyprotein 1a Severe acute respiratory syndrome coronavirus; SARS-CoVPLP_SARS1AP0C6U8 CHEMBL3927 315 / 329
papain-like protease Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2PLP_SARS2PLP
Replicase polyprotein 1ab Feline coronavirus; strain FIPV WSU-79/1146; FCoVPR_FCoVREPQ98VG9 CHEMBL4295624 12 / 12
Replicase polyprotein 1a Human coronavirus 229E; HCoV-229EPR_HCoV-229E1AP0C6U2
Replicase polyprotein 1a Human coronavirus NL63; HCoV-NL63PR_HCoV-NL631AP0C6U6 CHEMBL3232683 18 / 18
Replicase polyprotein 1a Human coronavirus HKU1; isolate N1; HCoV-HKU1PR_HKU11AP0C6U3
Replicase polyprotein 1ab Bat coronavirus HKU4; BtCoV; BtCoV/HKU4/2004PR_HKU4REPP0C6W3
3C-like proteinase Middle East respiratory syndrome-related coronavirus; MERS-CoVPR_MERsORF1AV9TU12
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus; SARS-CoVPR_SARSREPP0C6X7 CHEMBL5118 357 / 378
3C-like protease Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2PR_SARS2PR
Replicase polyprotein 1a Porcine transmissible gastroenteritis coronavirus; strain Purdue; TGEVPR_TGEV1AP0C6V2
RNA-dependent RNA polymerase Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2RDRP_SARS2RDRP
Spike glycoprotein Human coronavirus 229E; HCoV-229ESPIKE_HCoV-229ESP15423
Spike glycoprotein Human coronavirus NL63; HCoV-NL63SPIKE_HCoV-NL63SQ6Q1S2
Spike glycoprotein Human coronavirus OC43; HCoV-OC43SPIKE_HCoV-OC43SQ696P8
Spike glycoprotein Bat coronavirus HKU4; BtCoV; BtCoV/HKU4/2004SPIKE_HKU4SA3EX94
Spike glycoprotein Middle East respiratory syndrome-related coronavirus; isolate United Kingdom/H123990006/2012; MERS-CoV; Betacoronavirus England 1SPIKE_MERsSK9N5Q8
Spike protein Deltacoronavirus PDCoV/USA/Ohio137/2014SPIKE_PDCoVSA0A075E3D7
Spike glycoprotein Severe acute respiratory syndrome coronavirus; SARS-CoVSPIKE_SARSSP59594
Spike glycoprotein Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2SPIKE_SARS2SP0DTC2