| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.41 | -8.01 | -8.65 | 69.66% | CHEMBL3321796 | Active | 87.81% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.92 | -9.05 | -10.13 | 60.00% | CHEMBL361061 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.15 | -8.70 | -8.41 | 60.00% | CHEMBL361061 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.48 | -8.31 | -8.31 | 40.91% | CHEMBL105261 | Inactive | 67.99% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.24 | -9.09 | -9.31 | 60.00% | CHEMBL361061 | Active | 95.59% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.01 | -9.46 | N/A | 57.69% | CHEMBL352194 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.84 | -8.85 | -9.27 | 56.67% | CHEMBL3919861 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.93 | -9.90 | N/A | 57.69% | CHEMBL352194 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -9.24 | -9.31 | -8.24 | 44.20% | CHEMBL2179582 | Active | 56.30% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -9.01 | -7.03 | -8.24 | 48.28% | CHEMBL189262 | Inactive | 52.39% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -9.41 | -8.37 | -9.79 | 65.93% | CHEMBL3260790 | Active | 96.63% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.91 | -8.49 | -8.47 | 70.45% | CHEMBL3321797 | Active | 96.87% |
| AA1R_HUMAN | adenosine A1 receptor | -8.48 | -8.91 | -9.16 | 36.02% | CHEMBL1095812 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -8.58 | -8.21 | -8.85 | 47.29% | CHEMBL539454 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.56 | -9.09 | -8.66 | 34.19% | CHEMBL32447 | Active | 57.17% |
| AA3R_HUMAN | adenosine A3 receptor | -5.81 | -4.99 | -8.13 | 45.05% | CHEMBL11 | Active | 55.57% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.69 | -3.33 | N/A | 73.91% | CHEMBL1243110 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -8.95 | -8.34 | -8.19 | 82.93% | CHEMBL86309 | Active | 92.04% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -9.37 | -9.63 | -9.47 | 82.93% | CHEMBL86309 | Active | 97.48% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.53 | -9.18 | N/A | 68.48% | CHEMBL3354065 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -9.48 | -9.28 | -9.22 | 68.48% | CHEMBL3354078 | Active | 66.91% |
| ACTHR_HUMAN | melanocortin 2 receptor | -9.98 | -9.97 | -8.84 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.93 | -8.52 | -8.68 | 68.48% | CHEMBL4072818 | Active | 89.88% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -6.41 | -4.75 | 0.53 | 42.16% | CHEMBL395110 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -9.71 | -7.28 | -6.54 | 52.88% | CHEMBL279516 | Active | 54.38% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -1.26 | -1.97 | 9.55 | 52.88% | CHEMBL279516 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.22 | -8.83 | -8.48 | 56.88% | CHEMBL421030 | Active | 82.17% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -9.15 | -9.68 | -9.48 | 54.72% | CHEMBL1306990 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -9.36 | -9.30 | -8.69 | 56.88% | CHEMBL421030 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -9.77 | -10.07 | -9.94 | 36.50% | CHEMBL268815 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.05 | -9.53 | -9.43 | 51.02% | CHEMBL109123 | Active | 72.10% |
| CALCR_HUMAN | calcitonin receptor | -7.84 | -8.50 | -8.55 | 32.28% | CHEMBL2369895 | Inactive | 98.16% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.57 | -8.42 | -9.05 | 48.00% | CHEMBL105619 | Inactive | 71.63% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.24 | -8.28 | -8.56 | 64.56% | CHEMBL33761 | Active | 64.44% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.65 | -8.85 | -8.35 | 55.66% | CHEMBL2036755 | Active | 71.58% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -8.07 | -8.45 | -9.07 | 42.22% | CHEMBL395680 | Inactive | 60.05% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.22 | -8.85 | -8.47 | 78.16% | CHEMBL3104691 | Active | 93.01% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -7.95 | -9.96 | -9.38 | 38.58% | CHEMBL129866 | Inactive | 74.75% |
| CNR1_HUMAN | cannabinoid receptor 1 | -9.28 | -9.58 | -10.01 | 55.95% | CHEMBL479095 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -10.14 | -10.44 | N/A | 70.11% | CHEMBL2338188 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -4.57 | N/A | N/A | 31.10% | CHEMBL561812 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.65 | -7.17 | -7.69 | 33.87% | CHEMBL392181 | Inactive | 70.51% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.74 | -8.84 | -8.73 | 54.55% | CHEMBL252503 | Inactive | 62.54% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.63 | -7.40 | -7.60 | 41.88% | CHEMBL2371850 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.10 | -8.88 | -8.73 | 50.00% | CHEMBL476108 | Active | 75.56% |
| DRD2_HUMAN | dopamine receptor D2 | -8.17 | N/A | N/A | 70.79% | CHEMBL4091231 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -7.84 | N/A | N/A | 70.79% | CHEMBL4091231 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -9.29 | -9.39 | N/A | 70.79% | CHEMBL4074104 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -8.90 | -9.94 | -7.31 | 52.25% | CHEMBL394080 | Inactive | 53.28% |
| EDNRA_HUMAN | endothelin receptor type A | -7.63 | -7.64 | -7.88 | 38.19% | CHEMBL1793932 | Inactive | 63.71% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -1.85 | -2.87 | 9.21 | 21.48% | CHEMBL392394 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.49 | -7.93 | -6.69 | 50.00% | CHEMBL331929 | Inactive | 59.12% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -8.31 | -9.60 | -8.74 | 61.11% | CHEMBL2418383 | Active | 70.31% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -3.86 | -4.30 | -2.86 | 45.92% | CHEMBL3221831 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -4.64 | -5.57 | -6.58 | 34.82% | CHEMBL4095995 | Inactive | 72.16% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -0.55 | 0.07 | 0.60 | 43.62% | CHEMBL578358 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -8.18 | -9.30 | -9.17 | 47.52% | CHEMBL2338572 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -6.59 | -9.36 | -7.22 | 41.67% | CHEMBL2418359 | Inactive | 99.02% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -2.66 | -2.55 | -2.44 | 30.14% | CHEMBL3559748 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 3.44 | -0.96 | -0.47 | 41.67% | CHEMBL2418359 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -7.34 | N/A | N/A | 61.82% | CHEMBL1242923 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.91 | -9.08 | -9.89 | 40.57% | CHEMBL1627 | Active | 98.14% |
| HRH3_HUMAN | histamine receptor H3 | -7.96 | -9.19 | -8.20 | 65.91% | CHEMBL3949244 | Active | 93.76% |
| HRH4_HUMAN | histamine receptor H4 | -8.57 | -7.57 | -8.40 | 43.69% | CHEMBL4084275 | Active | 53.07% |
| MC3R_HUMAN | melanocortin 3 receptor | -8.54 | -8.28 | -9.12 | 46.97% | CHEMBL1089104 | Active | 72.23% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.73 | -7.20 | -7.28 | 54.70% | CHEMBL379051 | Inactive | 72.98% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.83 | -8.50 | -5.51 | 51.64% | CHEMBL3951865 | Inactive | 52.12% |
| MSHR_HUMAN | melanocortin 1 receptor | -8.55 | -8.57 | -7.99 | 44.64% | CHEMBL1091631 | Inactive | 66.40% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.94 | -7.69 | -8.18 | 63.92% | CHEMBL89245 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -8.77 | -9.01 | -9.13 | 50.82% | CHEMBL108997 | Inactive | 76.49% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.88 | -8.13 | -8.17 | 32.11% | CHEMBL1968640 | Inactive | 91.12% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.34 | -8.13 | -8.09 | 51.89% | CHEMBL3361410 | Active | 61.18% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -8.74 | -10.35 | -8.84 | 43.48% | CHEMBL1289780 | Active | 54.23% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.95 | -9.21 | -8.65 | 45.10% | CHEMBL564810 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.45 | -8.25 | -7.65 | 73.03% | CHEMBL1288048 | Active | 90.17% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.88 | -8.58 | -8.38 | 40.65% | CHEMBL2110365 | Inactive | 76.13% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.04 | -8.00 | -7.42 | 59.81% | CHEMBL2013017 | Active | 86.05% |
| OPRD_HUMAN | opioid receptor delta 1 | -8.32 | -7.55 | -7.57 | 100.00% | CHEMBL12391 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.70 | -8.66 | -9.15 | 100.00% | CHEMBL12391 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -9.26 | -7.67 | -8.25 | 100.00% | CHEMBL12391 | Active | 99.99% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.17 | -7.65 | -7.89 | 80.00% | CHEMBL317152 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.64 | -8.01 | -8.18 | 37.50% | CHEMBL52821 | Active | 56.27% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -10.16 | -9.51 | -9.29 | 65.98% | CHEMBL1337758 | Active | 59.43% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -9.58 | -9.89 | -9.53 | 50.00% | CHEMBL3908443 | Inactive | 80.92% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -8.03 | -8.28 | -8.65 | 50.00% | CHEMBL1807258 | Inactive | 55.79% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -9.03 | -8.71 | -9.35 | 31.43% | CHEMBL3884667 | N/A | N/A |