| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -6.88 | -6.34 | -7.09 | 36.00% | CHEMBL2164331 | Inactive | 65.46% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -7.52 | -7.49 | -7.43 | 28.00% | CHEMBL2112766 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -7.15 | -7.35 | -8.34 | 30.00% | CHEMBL139438 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -6.50 | -6.96 | -6.41 | 17.48% | CHEMBL4210782 | Inactive | 61.48% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -7.53 | -7.61 | -7.75 | 17.39% | CHEMBL39 | Inactive | 70.42% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -7.88 | -7.59 | N/A | 35.29% | CHEMBL471839 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -7.36 | -7.23 | -7.46 | 35.29% | CHEMBL471839 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -7.53 | -7.81 | N/A | 35.29% | CHEMBL471839 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -8.17 | -8.22 | -7.55 | 17.39% | CHEMBL39 | Inactive | 89.88% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -7.62 | -6.89 | -7.64 | 33.96% | CHEMBL494675 | Inactive | 57.62% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -7.03 | -6.64 | -7.11 | 34.62% | CHEMBL556759 | Inactive | 55.75% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -6.58 | -7.29 | -7.04 | 45.00% | CHEMBL234885 | Active | 55.66% |
| AA1R_HUMAN | adenosine A1 receptor | -7.37 | -7.86 | -7.73 | 28.12% | CHEMBL283196 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -7.90 | -7.65 | -7.64 | 27.69% | CHEMBL261185 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -6.65 | -6.94 | -6.09 | 20.93% | CHEMBL376778 | Inactive | 57.75% |
| AA3R_HUMAN | adenosine A3 receptor | -8.41 | -7.52 | -7.15 | 29.03% | CHEMBL2312728 | Active | 64.64% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.80 | -8.75 | N/A | 26.00% | CHEMBL657 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -7.28 | -6.44 | -7.70 | 26.00% | CHEMBL657 | Inactive | 63.64% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -6.21 | -7.20 | -7.98 | 30.51% | CHEMBL494410 | Inactive | 60.91% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.98 | -7.71 | N/A | 26.00% | CHEMBL657 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -7.36 | -7.30 | -7.45 | 26.00% | CHEMBL657 | Active | 57.50% |
| ACTHR_HUMAN | melanocortin 2 receptor | -9.16 | -8.89 | -7.29 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -6.65 | -6.63 | -6.59 | 25.00% | CHEMBL648 | Active | 51.19% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -7.77 | -7.36 | -5.54 | 29.27% | CHEMBL61006 | Active | 69.10% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -8.30 | -8.10 | -7.79 | 26.09% | CHEMBL972 | Active | 54.50% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -4.90 | -4.83 | -4.91 | 24.00% | CHEMBL1437 | Inactive | 54.49% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -6.98 | -7.45 | -7.43 | 30.51% | CHEMBL1621144 | Active | 61.67% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.98 | -8.16 | -7.85 | 33.96% | CHEMBL4062049 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -7.68 | -8.23 | -7.62 | 29.03% | CHEMBL507003 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -7.50 | -7.70 | -7.55 | 16.36% | CHEMBL290286 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -7.13 | -7.93 | -7.54 | 18.75% | CHEMBL121565 | Inactive | 92.96% |
| CALCR_HUMAN | calcitonin receptor | -6.80 | -6.58 | -6.82 | 8.16% | CHEMBL2369895 | Inactive | 97.34% |
| CCKAR_HUMAN | cholecystokinin A receptor | -7.07 | -6.95 | -7.95 | 16.67% | CHEMBL1210154 | Inactive | 98.80% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.70 | -8.08 | -6.61 | 21.43% | CHEMBL2205805 | Inactive | 98.29% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.13 | -6.85 | -6.50 | 24.00% | CHEMBL18442 | Inactive | 97.24% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -5.94 | -6.33 | -6.91 | 15.79% | CHEMBL1618631 | Inactive | 89.25% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -6.78 | -6.81 | -7.00 | 22.22% | CHEMBL106264 | Inactive | 99.74% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -6.84 | -7.46 | -8.01 | 13.85% | CHEMBL33329 | Inactive | 96.95% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.22 | -7.43 | -8.22 | 37.50% | CHEMBL3915185 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -8.21 | -8.33 | N/A | 38.30% | CHEMBL32362 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.23 | N/A | N/A | 18.75% | CHEMBL191413 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -7.29 | -5.66 | -5.83 | 18.75% | CHEMBL191413 | Inactive | 67.31% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -7.81 | -7.55 | -7.64 | 29.03% | CHEMBL2181446 | Inactive | 98.13% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.98 | -5.85 | -6.84 | 24.00% | CHEMBL18442 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -7.60 | -7.07 | -7.38 | 30.77% | CHEMBL441343 | Inactive | 75.08% |
| DRD2_HUMAN | dopamine receptor D2 | -8.09 | N/A | N/A | 28.57% | CHEMBL59 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -7.13 | N/A | N/A | 30.51% | CHEMBL484204 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -7.15 | -7.25 | N/A | 28.57% | CHEMBL59 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -7.15 | -7.96 | -7.64 | 28.57% | CHEMBL59 | Inactive | 82.39% |
| EDNRA_HUMAN | endothelin receptor type A | -5.39 | -5.87 | -6.11 | 20.45% | CHEMBL414408 | Inactive | 90.96% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -7.04 | -6.97 | -7.46 | 11.21% | CHEMBL2391908 | Inactive | 92.73% |
| GASR_HUMAN | cholecystokinin B receptor | -6.52 | -6.52 | -5.54 | 13.95% | CHEMBL38874 | Inactive | 95.35% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.77 | -7.73 | -7.61 | 20.45% | CHEMBL1269125 | Inactive | 77.61% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -7.60 | -8.66 | -8.05 | 26.09% | CHEMBL4634600 | Inactive | 51.79% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -9.26 | -9.53 | -9.25 | 19.67% | CHEMBL2112584 | Inactive | 66.25% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -5.95 | -5.77 | -5.93 | 17.78% | CHEMBL2022867 | Inactive | 90.65% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.72 | -9.44 | -9.45 | 26.09% | CHEMBL371811 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -7.89 | -8.15 | -7.71 | 16.22% | CHEMBL566136 | Inactive | 98.11% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.76 | -6.52 | -7.42 | 25.53% | CHEMBL1387826 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -6.42 | -7.29 | -7.01 | 17.14% | CHEMBL277475 | Inactive | 98.71% |
| HRH1_HUMAN | histamine receptor H1 | -7.87 | N/A | N/A | 28.57% | CHEMBL47482 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.00 | -7.92 | -8.99 | 20.69% | CHEMBL2207641 | Active | 78.51% |
| HRH3_HUMAN | histamine receptor H3 | -7.40 | -6.57 | -6.67 | 56.25% | CHEMBL209478 | Active | 87.58% |
| HRH4_HUMAN | histamine receptor H4 | -6.81 | -6.72 | -6.64 | 25.35% | CHEMBL4100315 | Active | 56.00% |
| MC3R_HUMAN | melanocortin 3 receptor | -8.03 | -7.39 | -7.23 | 14.63% | CHEMBL460142 | Inactive | 84.89% |
| MC4R_HUMAN | melanocortin 4 receptor | -5.80 | -5.87 | -6.39 | 27.27% | CHEMBL195009 | Inactive | 83.83% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.05 | -7.55 | -6.51 | 19.35% | CHEMBL3964883 | Inactive | 50.36% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.28 | -6.71 | -6.93 | 16.22% | CHEMBL267020 | Inactive | 75.24% |
| NK1R_HUMAN | tachykinin receptor 1 | -6.88 | -7.60 | -6.63 | 32.73% | CHEMBL206490 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -7.35 | -7.17 | -7.10 | 19.35% | CHEMBL17157 | Inactive | 99.16% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -6.47 | -6.03 | -6.48 | 14.06% | CHEMBL1991452 | Inactive | 95.59% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -6.63 | -6.25 | -6.42 | 21.05% | CHEMBL573297 | Inactive | 85.84% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -6.65 | -7.87 | -6.47 | 18.56% | CHEMBL1289780 | Inactive | 79.71% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -7.61 | -7.57 | -6.97 | 21.05% | CHEMBL3559801 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -6.80 | -6.37 | -6.37 | 21.05% | CHEMBL3559801 | Inactive | 85.78% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -6.73 | -6.63 | -6.26 | 21.05% | CHEMBL3559801 | Active | 91.43% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -6.56 | -6.64 | -6.47 | 26.67% | CHEMBL327027 | Inactive | 91.53% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.25 | -6.14 | -6.31 | 23.53% | CHEMBL127346 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -7.60 | -7.49 | -7.36 | 26.67% | CHEMBL4073160 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -7.31 | -6.23 | -6.56 | 26.67% | CHEMBL1188090 | Inactive | 91.27% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -6.42 | -6.36 | -6.32 | 22.22% | CHEMBL53256 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -7.88 | -8.18 | -8.30 | 19.78% | CHEMBL416120 | Inactive | 76.35% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -7.59 | -7.20 | -7.27 | 41.38% | CHEMBL610 | Active | 83.20% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -7.63 | -7.54 | -7.65 | 11.93% | CHEMBL3982371 | Inactive | 96.91% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -7.06 | -6.31 | -7.99 | 26.09% | CHEMBL1083095 | Inactive | 93.20% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -6.52 | -6.36 | -6.76 | 13.24% | CHEMBL1784685 | N/A | N/A |