Protein Targets

ProteinProtein nameOrganismSymbolGeneUniProtChEMBLCompounds
Genome polyprotein Human enterovirus 71; EV71; EV-712A_HE712AA9XG43
Genome polyprotein Human enterovirus 71; strain 7423/MS/87; EV71; EV-712A_HE71M2AQ66479
Genome polyprotein Human enterovirus 71; EV71; EV-712C_HE712CB9VUU3
Genome polyprotein Enterovirus F3A_9ENTO3AQ2LKY9
Genome polyprotein Human enterovirus 71; strain 7423/MS/87; EV71; EV-713A_HE71M3AQ66479
Genome polyprotein Human enterovirus D68; EV68; EV-683A_HED683AA0A2K9Y515
Genome polyprotein Human enterovirus 71; EV71; EV-713C_HE713CB8YLV9
Genome polyprotein Human enterovirus D68; EV68; EV-683C_HED683CA1E4A3
Genome polyprotein Human enterovirus 71; EV71; EV-713D_HE713DI3UIB4
Genome polyprotein Human enterovirus D68; EV68; EV-683D_HED683DF1T146
angiotensin converting enzyme 2 Homo sapiens; HumanACE2_HUMANACE2Q9BYF1 CHEMBL3736 107 / 107
Capsid protein Feline calicivirusCAPSD_9CALICAPSDA2T4Q0
Genome polyprotein Enterovirus FCAPSD_9ENTOCAPSDQ2LKZ0
Genome polyprotein Dengue virus type 2; strain Puerto Rico/PR159-S1/1969; DENV-2CAPSD_DEN2PCAPSDP12823 CHEMBL3308998 78 / 78
Genome polyprotein Hepatitis C virus genotype 1a; isolate H77; HCVCAPSD_HCV77CAPSDP27958 CHEMBL3638344 903 / 903
Capsid protein VP0 Human enterovirus D68; EV68; EV-68CAPSD_HED68VP1Q9YLJ3
Core protein Zika virus; ZIKVCAPSD_ZIKVCAPSDA0A0X8GJ44
DNA polymerase catalytic subunit Human herpesvirus 1; strain KOS; HHV-1; Human herpes simplex virus 1DPM_HHV1KUL30P04292 CHEMBL5944 4 / 5
Envelope glycoprotein E1 Hepacivirus CE1_9HEPCE1H9XGD6
Genome polyprotein Hepatitis C virus genotype 1a; isolate H77; HCVE1_HCV77E1P27958 CHEMBL3638344 903 / 903
Genome polyprotein Hepatitis C virus genotype 1b; isolate HC-J1; HCVE1_HCVJ1E1Q03463
Core protein precursor Hepacivirus CE2_9HEPCE2C1KH25
Genome polyprotein Hepatitis C virus genotype 1a; isolate H77; HCVE2_HCV77E2P27958 CHEMBL3638344 903 / 903
Envelope protein E Dengue virus 1ENV_9FLAVEQ8BE39
Genome polyprotein Dengue virus type 1; strain Brazil/97-11/1997; DENV-1ENV_DEN1BENVP27909
Genome polyprotein Dengue virus type 2; strain Puerto Rico/PR159-S1/1969; DENV-2ENV_DEN2PENVP12823 CHEMBL3308998 78 / 78
Genome polyprotein Dengue virus type 3; strain Philippines/H87/1956; DENV-3ENV_DEN3PENVP27915
Envelope glycoprotein H Human herpesvirus 2; strain HG52; HHV-2; Human herpes simplex virus 2ENV_HHV2HGHP89445
Core protein Zika virus; ZIKVENV_ZIKVENVA0A0X8GJ44
Genome polyprotein Zika virus; isolate ZIKV/Human/French Polynesia/10087PF/2013; ZIKVENV_ZIKVKENVA0A024B7W1
Envelope polyprotein Andes orthohantavirusG1_ADNVG1Q99BV0
Envelope polyprotein Andes orthohantavirusG2_ADNVMQ9E006
Envelope glycoprotein B Human herpesvirus 1; strain 17; HHV-1; Human herpes simplex virus 1GB_HHV11GBP10211 CHEMBL2364696
Envelope glycoprotein B Human herpesvirus 1; strain KOS; HHV-1; Human herpes simplex virus 1GB_HHV1KGBP06437
Glycoprotein D Suid alphaherpesvirus 1GD_9ALPHUS6G3G933
Glycoprotein D Human herpesvirus 1; HHV-1; Human herpes simplex virus 1GD_HHV1GDQ991M3
Envelope glycoprotein gp160 Human immunodeficiency virus 1GP160_HIV1ENVC6G099
Envelope glycoprotein gp160 Human immunodeficiency virus type 2 subtype A; isolate ST; HIV-2GP160_HIV2ENVP20872
Envelope glycoprotein Zaire ebolavirus; strain Mayinga-76; ZEBOV; Zaire Ebola virusGP_EBOVGPQ05320 CHEMBL4105829 32 / 32
Pre-glycoprotein polyprotein GP complex Lassa virus; strain Mouse/Sierra Leone/Josiah/1976; LASVGP_LASSJGPCP08669
Hemagglutinin Influenza A virus; strain A/Chicken/Germany/n/1949 H10N7HA_A-H10N7HAP12581
Hemagglutinin Influenza A virus; A/Jiangxi/IPB13/2013; H10N8HA_A-H10N8HAA0A059T4A1
Hemagglutinin Influenza A virus; strain A/Gull/Maryland/704/1977 H13N6HA_A-H13N6HAP13103
Hemagglutinin Influenza A virus; strain A/Mallard/Astrakhan/244/1982 H14N6; Influenza A virus; strain A/Mallard/Gurjev/244/1982 H14N6HA_A-H14N6HAP26137
Hemagglutinin Influenza A virus; A/shearWater/Australia/2576/1979; H15N9HA_A-H15N9HAL0L3X3
Hemagglutinin Influenza A virus; A/little yellow-shouldered bat/Guatemala/060/2010; H17N10HA_A-H17N10HAH6QM93
Hemagglutinin HA_A-H18N11HA
Hemagglutinin Influenza A virus; A/WDK/JX/12416/2005; H1N1HA_A-H1N1HAC7C6F1
Hemagglutinin Influenza A virus; strain A/Japan/305/1957 H2N2HA_A-H2N2HAP03451
Hemagglutinin Influenza A virusHA_A-H3N2HAK7N5L2 CHEMBL2366448 2 / 2
Hemagglutinin Influenza A virus; A/eq/Newmarket/93/; H3N8HA_A-H3N8HAIQ82847
Hemagglutinin Influenza A virus; A/Vietnam/1194/2004; H5N1HA_A-H5N1HAQ6DQ34
Hemagglutinin Influenza A virus; strain A/Duck/Singapore/3/1997 H5N3; Influenza A virus; strain A/Duck/Malaysia/F119-3/1997 H5N3HA_A-H5N3HAA5Z226
Hemagglutinin H6N1 subtypeHA_A-H6N1HAA0A0J9X268
Hemagglutinin Influenza A virus; A/chicken/Guangdong/S1414/2010; H6N6HA_A-H6N6HAA0A067YZ73
Hemagglutinin Influenza A virus; A/chicken/New Jersey/Sg-00421/2004; H7N2HA_A-H7N2HAB7NY59
Hemagglutinin Influenza A virus; A/Netherlands/219/2003; H7N7HA_A-H7N7HAQ6VMK1
Hemagglutinin Influenza A virus; A/Hangzhou/1/2013; H7N9HA_A-H7N9HAM4YV75
Hemagglutinin Influenza B virus; strain B/Hong Kong/8/1973HA_INFBHAP03462
Hemagglutinin-esterase-fusion glycoprotein Influenza D virus; D/swine/Oklahoma/1334/2011HA_INFDHEFK9LG83
Hemagglutinin-esterase Bovine coronavirus; strain Mebus; BCoV; BCVHE_BCVHEP15776
Hemagglutinin-esterase Human coronavirus OC43; HCoV-OC43HE_HCoV-OC43HEQ4VID6
Hemagglutinin-esterase Murine coronavirus; strain DVIM; MHV-DVIM; Murine hepatitis virusHE_MHVHEO92367
Gag-Pol polyprotein Human immunodeficiency virus type 1 group M subtype B; isolate NY5; HIV-1IN_HIV1GAG-POLP12497
Replicase polyprotein 1ab Bat coronavirus HKU4; BtCoV; BtCoV/HKU4/2004MD_HKU4REPP0C6W3
Replicase polyprotein 1a Middle East respiratory syndrome-related coronavirus; isolate United Kingdom/H123990006/2012; MERS-CoV; Betacoronavirus England 1MD_MERs1AK9N638
Core protein Dengue virus 2MEM_9FLAVMEMO11875
Methyltransferase Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2MTASE_SARS2MTASE
Methyltransferase Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2MTASE_SARS2MTASE
Matrix protein 2 Influenza A virus; strain A/Goose/Guangdong/1/1996 H5N1 genotype Gs/GdMX2_A-H5N1MQ9Q0L9
Matrix protein VP40 Sudan ebolavirusMX_9MONOVP40B0LPL6
RING finger protein Z Lassa virus; strain Mouse/Sierra Leone/Josiah/1976; LASVMX_LASSJZO73557
Neuraminidase Influenza A virus; strain A/Duck/England/1/1956 H11N6NA_A-H11N6NAQ6XV27
Neuraminidase Influenza A virus; strain A/Tern/Australia/G70C/1975 H11N9NA_A-H11N9NAP03472
Neuraminidase Influenza A virus; strain A/Duck/Alberta/60/1976 H12N5NA_A-H12N5NAA1ILL9
Neuraminidase Influenza A virus; strain A/Whale/Maine/1/1984 H13N9NA_A-H13N9NAP05803
Neuraminidase Influenza A virus; A/little yellow-shouldered bat/Guatemala/164/2009; H17N10NA_A-H17N10NAH6QM85
Neuraminidase NA_A-H18N11NA
Neuraminidase Influenza A virus; A/Texas/17/2009; H1N1NA_A-H1N1NAC6KP13
Neuraminidase Influenza A virus; strain A/Tokyo/3/1967 H2N2NA_A-H2N2NAP06820
Ig heavy chain Mem5 Mus musculus; MouseNA_A-H3N2NAP84751
Neuraminidase Influenza A virus; strain A/Duck/Ukraine/1/1963 H3N8NA_A-H3N8NAQ07599 CHEMBL4295592 14 / 14
Neuraminidase Influenza A virus; A/American green-winged teal/Washington/195750/2014; H5N1NA_A-H5N1NAA0A0C5BL75
Neuraminidase Influenza A virus; A/Shanghai/02/2013; H7N9NA_A-H7N9NAR4NFR6
Neuraminidase Influenza B virus; strain B/Lee/1940NA_INFBNAP03474 CHEMBL3377 372 / 392
Nucleoprotein Andes orthohantavirusNP_9ADNVNPQ80DP9
Nucleoprotein Influenza A virus; strain A/Wilson-Smith/1933 H1N1; Influenza A virus; strain A/WS/1933 H1N1NP_A-H1N1NPQ1K9H2
Nucleoprotein Influenza A virus; A/Chicken/Hong Kong/786/97; H5N1NP_A-H5N1NPQ9PX50
Nucleoprotein Zaire ebolavirus; strain Mayinga-76; ZEBOV; Zaire Ebola virusNP_EBOZMNPP18272
Nucleoprotein Human coronavirus NL63; HCoV-NL63NP_HCoV-NL63NQ6Q1R8
Nucleoprotein Human coronavirus OC43; HCoV-OC43NP_HCoV-OC43NP33469 CHEMBL3232681 4 / 4
Nucleoprotein Influenza B virus; B/Managua/4577.01/2008NP_INFBNPC4LQ26
NP Influenza D virus; D/bovine/France/2986/2012NP_INFDNPA0A0E3VZU8
Nucleoprotein Lassa virus; strain Mouse/Sierra Leone/Josiah/1976; LASVNP_LASSJNP13699
Nucleoprotein Severe acute respiratory syndrome coronavirus; SARS-CoVNP_SARSNP59595
NTPase Murine norovirus 1NS1_9CALINS1Q80J95
Non-structural protein 1 Dengue virus 2NS1_9FLAVNS1Q6TFL7
Genome polyprotein Dengue virus type 1; strain Nauru/West Pac/1974; DENV-1NS1_DEN1WNS1P17763
Core protein Zika virus; ZIKVNS1_ZIKVNS1A0A109PRQ3
Core protein Dengue virus 2NS2A_9FLAVNS2AQ9YKL3
Genome polyprotein Dengue virus type 1; strain Nauru/West Pac/1974; DENV-1NS2B_DEN1WNS2BP17763
Genome polyprotein Dengue virus type 2; strain Puerto Rico/PR159-S1/1969; DENV-2NS2B_DEN2PNS2BP12823 CHEMBL3308998 78 / 78
Genome polyprotein Zika virus; ZIKVNS2B_ZIKVNS2BQ32ZE1 CHEMBL4523307 20 / 22
Genome polyprotein Zika virus; isolate ZIKV/Human/French Polynesia/10087PF/2013; ZIKVNS2B_ZIKVFNS2BA0A024B7W1
Core protein Dengue virus 4NS3_9FLAVNS3F8TEL4
Genome polyprotein Dengue virus type 4; strain Thailand/0348/1991; DENV-4NS3_DEN4TNS3Q2YHF0
Genome polyprotein Hepatitis C virus genotype 1a; isolate H77; HCVNS3_HCV1ANS3P27958 CHEMBL3638344 903 / 903
Genome polyprotein Hepacivirus CNS3_HCV1BNS3Q91RS4 CHEMBL3988605 24 / 0
Genome polyprotein Hepacivirus CNS3_HCV3ANS3A0A0B4WYC6
Genome polyprotein Zika virus; ZIKVNS3_ZIKVNS3Q32ZE1 CHEMBL4523307 20 / 22
Genome polyprotein Hepatitis C virus genotype 1a; isolate 1; HCVNS5B_HCV1ANS5BP26664 CHEMBL4620 243 / 244
Genome polyprotein Hepatitis C virus genotype 1b; isolate BK; HCVNS5B_HCV1BNS5BP26663 CHEMBL6040 50 / 50
Genome polyprotein Hepatitis C virus genotype 2a; isolate JFH-1; HCVNS5B_HCV2ANS5BQ99IB8 CHEMBL4295932 4 / 4
Core protein Dengue virus 2NS5_9FLAVNS5H9M652
Genome polyprotein Dengue virus type 3; strain Sri Lanka/1266/2000; DENV-3NS5_DEN3SPOLQ6YMS4
Genome polyprotein Zika virus; ZIKVNS5_ZIKVNS5Q32ZE1 CHEMBL4523307 20 / 22
Genome polyprotein Zika virus; isolate ZIKV/Human/French Polynesia/10087PF/2013; ZIKVNS5_ZIKVFNS5A0A024B7W1
NTPase Murine norovirus 1NS6_9CALINS6Q80J95
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus; SARS-CoVNSP15_SARSREPP0C6X7 CHEMBL5118 357 / 378
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2NSP15_SARS2NSP15
Non-structural protein 1 Influenza B virus; strain B/Lee/1940NSP1_INFBNSP03502
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus; SARS-CoVNSP1_SARSREPP0C6X7 CHEMBL5118 357 / 378
Replicase polyprotein 1a Human coronavirus 229E; HCoV-229ENSP3_HCoV-229E1AP0C6U2
Replicase polyprotein 1a Avian infectious bronchitis virus; strain M41; IBVNSP3_IBV1AP0C6V5
Replicase polyprotein 1ab Murine coronavirus; strain A59; MHV-A59; Murine hepatitis virusNSP3_MHVREPP0C6X9
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2NSP3_SARS2NSP3
Replicase polyprotein 1ab Human coronavirus 229E; HCoV-229ENSP9_HCoV-229EREPP0C6X1
Polymerase acidic protein Influenza A virus; A/little yellow-shouldered bat/Guatemala/060/2010; H17N10PA_A-H17N10PAH6QM92
Polymerase acidic protein Influenza A virus; strain swl A/California/04/2009 H1N1PA_A-H1N1PAC3W5S0
Polymerase acidic protein Influenza A virus; strain A/Goose/Guangdong/1/1996 H5N1 genotype Gs/GdPA_A-H5N1PAQ9Q0U9
Polymerase acidic protein Influenza A virus; strain A/Puerto Rico/8/1934 H1N1PA_INFAPAP03433 CHEMBL1169598 788 / 789
Polymerase acidic protein Influenza B virus; B/Memphis/13/2003PA_INFBPAQ5V8Z9
Polymerase basic protein 2 Influenza A virus; strain A/Beijing/39/1975 H3N2PB2_A-H3N2PB2Q30NP1
Polymerase basic protein 2 Influenza A virus; A/duck/Shantou/4610/2003; H5N1PB2_A-H5N1PB2Q2LG68
Polymerase basic protein 2 Influenza B virus; strain B/Lee/1940PB2_INFBPB2Q9QLL6
Polymerase basic protein 2 Influenza A virus; strain A/Beijing/39/1975 H3N2PB3_A-H3N2PB2Q30NP1
Polymerase basic protein 2 Influenza A virus; strain A/Beijing/39/1975 H3N2PB4_A-H3N2PB2Q30NP1
Replicase polyprotein 1a Severe acute respiratory syndrome coronavirus; SARS-CoVPLP_SARS1AP0C6U8 CHEMBL3927 315 / 329
papain-like protease Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2PLP_SARS2PLP
RNA-directed RNA polymerase L Lassa mammarenavirusPM_9VIRULA0A097F4L1
Replicase polyprotein 1ab Feline coronavirus; strain FIPV WSU-79/1146; FCoVPR_FCoVREPQ98VG9 CHEMBL4295624 12 / 12
Replicase polyprotein 1a Human coronavirus 229E; HCoV-229EPR_HCoV-229E1AP0C6U2
Replicase polyprotein 1a Human coronavirus NL63; HCoV-NL63PR_HCoV-NL631AP0C6U6 CHEMBL3232683 18 / 18
Gag-Pol polyprotein Human immunodeficiency virus type 1 group M subtype B; isolate ARV2/SF2; HIV-1PR_HIV1GAG-POLP03369 CHEMBL3638331 20 / 20
Gag-Pol polyprotein Human immunodeficiency virus type 2 subtype A; isolate ROD; HIV-2PR_HIV2GAG-POLP04584
Replicase polyprotein 1a Human coronavirus HKU1; isolate N1; HCoV-HKU1PR_HKU11AP0C6U3
Replicase polyprotein 1ab Bat coronavirus HKU4; BtCoV; BtCoV/HKU4/2004PR_HKU4REPP0C6W3
Replicase polyprotein 1a Avian infectious bronchitis virus; strain M41; IBVPR_IBV1AP0C6V5
3C-like proteinase Middle East respiratory syndrome-related coronavirus; MERS-CoVPR_MERsORF1AV9TU12
3C-like proteinase Porcine epidemic diarrhea virusPR_PEDVORF1AU6BPB2
Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus; SARS-CoVPR_SARSREPP0C6X7 CHEMBL5118 357 / 378
3C-like protease Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2PR_SARS2PR
Replicase polyprotein 1a Porcine transmissible gastroenteritis coronavirus; strain Purdue; TGEVPR_TGEV1AP0C6V2
Norovirus P domain protein Alphatron virusP_9CALIPA0A509GV46
Capsid protein VP1 Norwalk virus; strain GI/Human/United States/Norwalk/1968; Hu/NV/NV/1968/USP_NVN68ORF2Q83884
RNA-dependent RNA polymerase Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2RDRP_SARS2RDRP
Gag-Pol polyprotein Human immunodeficiency virus type 1 group M subtype B; isolate HXB2; HIV-1RT_HIV1GAG-POLP04585 CHEMBL3638360 360 / 363
Spike glycoprotein Human coronavirus 229E; HCoV-229ESPIKE_HCoV-229ESP15423
Spike glycoprotein Human coronavirus NL63; HCoV-NL63SPIKE_HCoV-NL63SQ6Q1S2
Spike glycoprotein Human coronavirus OC43; HCoV-OC43SPIKE_HCoV-OC43SQ696P8
Spike glycoprotein Bat coronavirus HKU4; BtCoV; BtCoV/HKU4/2004SPIKE_HKU4SA3EX94
Spike glycoprotein Infectious bronchitis virusSPIKE_IBVSPIKEF4MIW6
Spike glycoprotein Middle East respiratory syndrome-related coronavirus; isolate United Kingdom/H123990006/2012; MERS-CoV; Betacoronavirus England 1SPIKE_MERsSK9N5Q8
Spike glycoprotein Murine hepatitis virusSPIKE_MHVORF3Q9J3E7
Spike protein Deltacoronavirus PDCoV/USA/Ohio137/2014SPIKE_PDCoVSA0A075E3D7
Spike glycoprotein Severe acute respiratory syndrome coronavirus; SARS-CoVSPIKE_SARSSP59594
Spike glycoprotein Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; SARS-CoV-2SPIKE_SARS2SP0DTC2
Capsid protein Murine norovirus 1VP1_9CALIVP1Q2V8W4
Capsid protein VP1 Norwalk virus; strain GI/Human/United States/Norwalk/1968; Hu/NV/NV/1968/USVP1_NVN68ORF2Q83884
Membrane-associated protein VP24 Reston ebolavirus; strain Philippines-96; REBOV; Reston Ebola virusVP24_EBOREVP24Q91DD5
Membrane-associated protein VP24 Sudan ebolavirus; strain Human/Uganda/Gulu/2000; SEBOV; Sudan Ebola virusVP24_EBOSUVP24Q5XX02
Membrane-associated protein VP24 Zaire ebolavirus; strain Mayinga-76; ZEBOV; Zaire Ebola virusVP24_EBOZMVP24Q05322
Minor nucleoprotein VP30 Mengla dianlovirusVP30_9MONOVP30A0A3S8UVN5
Transcriptional activator VP30 Zaire ebolavirus; strain Kikwit-95; ZEBOV; Zaire Ebola virusVP30_EBOZ5VP30Q77DJ5
Transcriptional activator VP30 Zaire ebolavirus; strain Mayinga-76; ZEBOV; Zaire Ebola virusVP30_EBOZMVP30Q05323
Polymerase cofactor VP35 Reston ebolavirus; strain Reston-89; REBOV; Reston Ebola virusVP35_EBORRVP35Q8JPY0
Polymerase cofactor VP35 Zaire ebolavirus; strain Mayinga-76; ZEBOV; Zaire Ebola virusVP35_EBOZMVP35Q05127
Matrix protein VP40 Zaire ebolavirus; strain Mayinga-76; ZEBOV; Zaire Ebola virusVP40_EBOZMVP40Q05128