| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.72 | -8.56 | -8.12 | 31.17% | CHEMBL1255002 | Inactive | 67.15% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -10.02 | -9.94 | -10.34 | 25.30% | CHEMBL3139682 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -10.12 | -9.48 | -9.67 | 26.47% | CHEMBL2260921 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -9.52 | -9.23 | -8.71 | 25.30% | CHEMBL3139682 | Inactive | 60.92% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.65 | -10.16 | -9.73 | 25.30% | CHEMBL3139682 | Inactive | 71.54% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -10.28 | -10.83 | N/A | 35.48% | CHEMBL420 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -10.13 | -10.38 | -10.83 | 37.50% | CHEMBL493128 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -10.18 | -10.05 | N/A | 40.24% | CHEMBL1092167 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -11.70 | -11.70 | -9.52 | 25.30% | CHEMBL3139682 | Inactive | 77.62% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.85 | -7.70 | -9.08 | 27.03% | CHEMBL189262 | Inactive | 72.49% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -9.76 | -9.39 | -10.52 | 34.55% | CHEMBL1670 | Active | 78.94% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.79 | -8.78 | -8.62 | 32.89% | CHEMBL3961059 | Inactive | 62.41% |
| AA1R_HUMAN | adenosine A1 receptor | -9.27 | -9.46 | -8.26 | 32.95% | CHEMBL3982084 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -9.92 | -9.84 | -10.29 | 34.85% | CHEMBL496 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.81 | -9.34 | -8.79 | 26.61% | CHEMBL2024112 | Active | 54.85% |
| AA3R_HUMAN | adenosine A3 receptor | -8.75 | -4.78 | -5.45 | 34.85% | CHEMBL496 | Active | 61.25% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.13 | 5.40 | N/A | 37.50% | CHEMBL1084850 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.74 | -8.98 | -7.80 | 28.38% | CHEMBL1290183 | Inactive | 59.26% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.98 | -10.45 | -9.94 | 37.50% | CHEMBL1084850 | Active | 59.87% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.19 | -8.23 | N/A | 23.60% | CHEMBL809 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -8.96 | -9.82 | -9.61 | 23.60% | CHEMBL809 | Active | 56.79% |
| ACTHR_HUMAN | melanocortin 2 receptor | -10.53 | -10.36 | -8.20 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -9.69 | -8.47 | -9.37 | 35.48% | CHEMBL420 | Inactive | 53.11% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -3.92 | -1.92 | 5.61 | 35.48% | CHEMBL420 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -9.80 | -9.27 | -9.64 | 35.48% | CHEMBL420 | Inactive | 50.72% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -4.67 | -3.82 | 1.51 | 35.48% | CHEMBL420 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.97 | -10.00 | -9.97 | 40.79% | CHEMBL269823 | Active | 57.53% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -9.46 | -10.40 | -10.61 | 33.80% | CHEMBL49080 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -10.05 | -11.11 | -9.76 | 40.79% | CHEMBL269823 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -8.73 | -9.27 | -8.86 | 19.17% | CHEMBL290286 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.90 | -9.97 | -9.71 | 19.84% | CHEMBL551435 | Inactive | 80.00% |
| CALCR_HUMAN | calcitonin receptor | -8.73 | -9.06 | -8.56 | 8.95% | CHEMBL2369897 | Inactive | 99.03% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.56 | -7.41 | -8.63 | 18.75% | CHEMBL206025 | Inactive | 97.17% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.67 | -8.73 | -8.68 | 31.58% | CHEMBL2205805 | Inactive | 71.01% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.62 | -8.45 | -8.55 | 25.22% | CHEMBL337720 | Inactive | 80.28% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.89 | -9.07 | -9.29 | 21.10% | CHEMBL233047 | Inactive | 61.38% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.41 | -8.89 | -8.68 | 24.42% | CHEMBL94032 | Inactive | 95.16% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.77 | -10.10 | -9.49 | 18.83% | CHEMBL416769 | Inactive | 85.64% |
| CNR1_HUMAN | cannabinoid receptor 1 | -8.91 | -8.47 | -8.79 | 57.89% | CHEMBL3950898 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -10.40 | -9.61 | N/A | 57.89% | CHEMBL3950898 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -0.87 | N/A | N/A | 25.61% | CHEMBL139 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.09 | -7.40 | -7.45 | 21.93% | CHEMBL82566 | Inactive | 68.44% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -10.91 | -10.57 | -10.82 | 46.97% | CHEMBL2181445 | Active | 70.58% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -10.04 | -7.02 | -8.81 | 21.88% | CHEMBL2311089 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.67 | -9.00 | -9.22 | 27.06% | CHEMBL383451 | Inactive | 62.67% |
| DRD2_HUMAN | dopamine receptor D2 | -9.86 | N/A | N/A | 30.16% | CHEMBL2048227 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -9.60 | N/A | N/A | 28.12% | CHEMBL374749 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -9.85 | -9.66 | N/A | 32.14% | CHEMBL366043 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -7.74 | -10.64 | -9.84 | 27.06% | CHEMBL383451 | Inactive | 71.77% |
| EDNRA_HUMAN | endothelin receptor type A | -7.69 | -7.74 | -7.95 | 26.47% | CHEMBL283200 | Inactive | 68.94% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 0.68 | -8.41 | 30.65 | 18.58% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.25 | -7.84 | -7.40 | 22.77% | CHEMBL537171 | Inactive | 83.67% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -11.21 | -10.82 | -10.22 | 22.22% | CHEMBL1269125 | Inactive | 55.62% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -4.00 | -5.77 | -1.07 | 35.63% | CHEMBL503697 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -4.87 | -7.41 | -8.25 | 26.25% | CHEMBL333771 | Inactive | 95.07% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 2.86 | 1.54 | 2.79 | 23.36% | CHEMBL2023456 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -10.37 | -5.62 | -4.04 | 32.29% | CHEMBL3603919 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -2.71 | -7.82 | -2.37 | 16.13% | CHEMBL566136 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | 2.76 | -0.62 | -0.12 | 11.26% | CHEMBL3560922 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 6.27 | 5.96 | 6.01 | 18.07% | CHEMBL143210 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -9.78 | N/A | N/A | 26.60% | CHEMBL105385 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.13 | -8.71 | -8.84 | 26.47% | CHEMBL2207642 | Active | 82.76% |
| HRH3_HUMAN | histamine receptor H3 | -8.58 | -9.53 | -8.80 | 44.44% | CHEMBL209478 | Active | 59.79% |
| HRH4_HUMAN | histamine receptor H4 | -10.18 | -9.66 | -9.67 | 32.26% | CHEMBL1934049 | Inactive | 76.68% |
| MC3R_HUMAN | melanocortin 3 receptor | -9.60 | -9.16 | -9.01 | 20.00% | CHEMBL185862 | Inactive | 72.02% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.76 | -7.31 | -8.16 | 29.29% | CHEMBL226177 | Inactive | 87.60% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.72 | -9.60 | -6.00 | 24.56% | CHEMBL3940009 | Inactive | 95.18% |
| MSHR_HUMAN | melanocortin 1 receptor | -8.07 | -8.48 | -7.80 | 17.73% | CHEMBL2371969 | Inactive | 85.65% |
| NK1R_HUMAN | tachykinin receptor 1 | -9.00 | -9.50 | -9.62 | 35.71% | CHEMBL92032 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -9.68 | -9.93 | -10.13 | 27.10% | CHEMBL3642161 | Inactive | 66.58% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -8.07 | -8.28 | -7.42 | 15.58% | CHEMBL2314317 | Inactive | 96.27% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -9.40 | -9.11 | -7.91 | 29.73% | CHEMBL575058 | Inactive | 68.00% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -9.23 | -10.75 | -8.90 | 16.07% | CHEMBL1289780 | Inactive | 58.42% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -10.03 | -8.65 | -8.98 | 18.27% | CHEMBL551876 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.25 | -8.99 | -7.87 | 21.48% | CHEMBL1398754 | Inactive | 95.85% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -9.03 | -9.57 | -9.50 | 16.67% | CHEMBL3559801 | Inactive | 99.63% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.12 | -7.96 | -7.78 | 30.11% | CHEMBL332561 | Inactive | 88.51% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.74 | -6.25 | -7.09 | 26.50% | CHEMBL250186 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.86 | -9.89 | -8.31 | 28.38% | CHEMBL102999 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.54 | -7.21 | -8.26 | 26.67% | CHEMBL1818338 | Inactive | 84.04% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.49 | -7.79 | -8.52 | 26.32% | CHEMBL320991 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.80 | -9.59 | -9.87 | 20.39% | CHEMBL416120 | Inactive | 67.10% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -10.18 | -10.36 | -9.47 | 45.65% | CHEMBL274497 | Inactive | 52.89% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -9.59 | -11.33 | -9.46 | 18.26% | CHEMBL4114422 | Inactive | 92.12% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -9.50 | -8.48 | -8.84 | 36.47% | CHEMBL1085123 | Inactive | 56.34% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.68 | -8.06 | -8.14 | 14.20% | CHEMBL520349 | N/A | N/A |