Nirmatrelvir modification 02 #419 Output Download CSV

Gene Protein
 
  The docking scores are in the AutoDock Vina metric.
Ligand Protein Symbol Approved Name Docking Scores Similarity
Score 		Best Match
Model 1 Model 2 Model 3
Nirmatrelvir 2A_HE71 Genome polyprotein -7.45 N/A N/A N/A N/A
Nirmatrelvir Modify 02 2A_HE71 Genome polyprotein -9.18 N/A N/A N/A N/A
Nirmatrelvir 2A_HE71M Genome polyprotein -8.46 N/A N/A N/A N/A
Nirmatrelvir Modify 02 2A_HE71M Genome polyprotein -8.88 N/A N/A N/A N/A
Nirmatrelvir 2C_HE71 Genome polyprotein -5.43 -6.52 N/A N/A N/A
Nirmatrelvir Modify 02 2C_HE71 Genome polyprotein -5.92 -7.90 N/A N/A N/A
Nirmatrelvir 3A_9ENTO Genome polyprotein -5.72 N/A N/A N/A N/A
Nirmatrelvir Modify 02 3A_9ENTO Genome polyprotein -6.00 N/A N/A N/A N/A
Nirmatrelvir 3A_HE71M Genome polyprotein -4.89 N/A N/A N/A N/A
Nirmatrelvir Modify 02 3A_HE71M Genome polyprotein -5.49 N/A N/A N/A N/A
Nirmatrelvir 3A_HED68 Genome polyprotein -4.98 N/A N/A N/A N/A
Nirmatrelvir Modify 02 3A_HED68 Genome polyprotein -6.72 N/A N/A N/A N/A
Nirmatrelvir 3C_HE71 Genome polyprotein -6.50 -6.06 N/A N/A N/A
Nirmatrelvir Modify 02 3C_HE71 Genome polyprotein -6.84 -6.98 N/A N/A N/A
Nirmatrelvir 3C_HED68 Genome polyprotein -6.33 N/A N/A N/A N/A
Nirmatrelvir Modify 02 3C_HED68 Genome polyprotein -6.57 N/A N/A N/A N/A
Nirmatrelvir 3D_HE71 Genome polyprotein -7.73 N/A N/A N/A N/A
Nirmatrelvir Modify 02 3D_HE71 Genome polyprotein -8.26 N/A N/A N/A N/A
Nirmatrelvir 3D_HED68 Genome polyprotein -7.99 N/A N/A N/A N/A
Nirmatrelvir Modify 02 3D_HED68 Genome polyprotein -8.88 N/A N/A N/A N/A
Nirmatrelvir ACE2_HUMAN angiotensin converting enzyme 2 -9.56 N/A N/A 38.64% CHEMBL254900
Nirmatrelvir Modify 02 ACE2_HUMAN angiotensin converting enzyme 2 -11.11 N/A N/A 52.10% CHEMBL400526
Nirmatrelvir CAPSD_9CALI Capsid protein -7.98 -6.68 -7.93 N/A N/A
Nirmatrelvir Modify 02 CAPSD_9CALI Capsid protein -8.61 -7.71 -8.66 N/A N/A
Nirmatrelvir CAPSD_9ENTO Genome polyprotein -6.30 N/A N/A N/A N/A
Nirmatrelvir Modify 02 CAPSD_9ENTO Genome polyprotein -7.85 N/A N/A N/A N/A
Nirmatrelvir CAPSD_DEN2P Genome polyprotein -5.95 N/A N/A N/A N/A
Nirmatrelvir Modify 02 CAPSD_DEN2P Genome polyprotein -7.17 N/A N/A N/A N/A
Nirmatrelvir CAPSD_HCV77 Genome polyprotein -4.38 N/A N/A 60.67% CHEMBL296588
Nirmatrelvir Modify 02 CAPSD_HCV77 Genome polyprotein -5.21 N/A N/A 45.76% CHEMBL296588
Nirmatrelvir CAPSD_HED68 Capsid protein VP0 -8.13 -9.58 N/A N/A N/A
Nirmatrelvir Modify 02 CAPSD_HED68 Capsid protein VP0 -8.88 -9.93 N/A N/A N/A
Nirmatrelvir CAPSD_ZIKV Core protein -6.13 -5.91 N/A N/A N/A
Nirmatrelvir Modify 02 CAPSD_ZIKV Core protein -6.77 -6.62 N/A N/A N/A
Nirmatrelvir DPM_HHV1K DNA polymerase catalytic subunit -7.76 N/A N/A 16.31% CHEMBL479371
Nirmatrelvir Modify 02 DPM_HHV1K DNA polymerase catalytic subunit -8.95 N/A N/A 24.48% CHEMBL479371
Nirmatrelvir E1_9HEPC Envelope glycoprotein E1 -5.33 N/A N/A N/A N/A
Nirmatrelvir Modify 02 E1_9HEPC Envelope glycoprotein E1 -5.96 N/A N/A N/A N/A
Nirmatrelvir E1_HCV77 Genome polyprotein -4.66 N/A N/A 60.67% CHEMBL296588
Nirmatrelvir Modify 02 E1_HCV77 Genome polyprotein -4.60 N/A N/A 45.76% CHEMBL296588
Nirmatrelvir E1_HCVJ1 Genome polyprotein -4.49 N/A N/A N/A N/A
Nirmatrelvir Modify 02 E1_HCVJ1 Genome polyprotein -4.94 N/A N/A N/A N/A
Nirmatrelvir E2_9HEPC Core protein precursor -7.81 N/A N/A N/A N/A
Nirmatrelvir Modify 02 E2_9HEPC Core protein precursor -8.57 N/A N/A N/A N/A
Nirmatrelvir E2_HCV77 Genome polyprotein -5.82 N/A N/A 60.67% CHEMBL296588
Nirmatrelvir Modify 02 E2_HCV77 Genome polyprotein -6.38 N/A N/A 45.76% CHEMBL296588
Nirmatrelvir ENV_9FLAV Envelope protein E -5.89 N/A N/A N/A N/A
Nirmatrelvir Modify 02 ENV_9FLAV Envelope protein E -5.80 N/A N/A N/A N/A
Nirmatrelvir ENV_DEN1B Genome polyprotein -5.39 N/A N/A N/A N/A
Nirmatrelvir Modify 02 ENV_DEN1B Genome polyprotein -5.27 N/A N/A N/A N/A
Nirmatrelvir ENV_DEN2P Genome polyprotein -7.00 N/A N/A N/A N/A
Nirmatrelvir Modify 02 ENV_DEN2P Genome polyprotein -6.88 N/A N/A N/A N/A
Nirmatrelvir ENV_DEN3P Genome polyprotein -5.60 N/A N/A N/A N/A
Nirmatrelvir Modify 02 ENV_DEN3P Genome polyprotein -6.35 N/A N/A N/A N/A
Nirmatrelvir ENV_HHV2H Envelope glycoprotein H -6.84 N/A N/A N/A N/A
Nirmatrelvir Modify 02 ENV_HHV2H Envelope glycoprotein H -7.74 N/A N/A N/A N/A
Nirmatrelvir ENV_ZIKV Core protein -5.67 N/A N/A N/A N/A
Nirmatrelvir Modify 02 ENV_ZIKV Core protein -6.72 N/A N/A N/A N/A
Nirmatrelvir ENV_ZIKVK Genome polyprotein -6.46 N/A N/A N/A N/A
Nirmatrelvir Modify 02 ENV_ZIKVK Genome polyprotein -6.51 N/A N/A N/A N/A
Nirmatrelvir G1_ADNV Envelope polyprotein -3.85 -6.25 -6.33 N/A N/A
Nirmatrelvir Modify 02 G1_ADNV Envelope polyprotein -4.33 -6.77 -6.82 N/A N/A
Nirmatrelvir G2_ADNV Envelope polyprotein -7.41 -6.92 -6.95 N/A N/A
Nirmatrelvir Modify 02 G2_ADNV Envelope polyprotein -8.68 -9.29 -7.63 N/A N/A
Nirmatrelvir GB_HHV11 Envelope glycoprotein B -7.10 N/A N/A N/A N/A
Nirmatrelvir Modify 02 GB_HHV11 Envelope glycoprotein B -7.54 N/A N/A N/A N/A
Nirmatrelvir GB_HHV1K Envelope glycoprotein B -7.10 -6.68 N/A N/A N/A
Nirmatrelvir Modify 02 GB_HHV1K Envelope glycoprotein B -8.57 -8.32 N/A N/A N/A
Nirmatrelvir GD_9ALPH Glycoprotein D -7.63 -5.57 N/A N/A N/A
Nirmatrelvir Modify 02 GD_9ALPH Glycoprotein D -8.54 -6.65 N/A N/A N/A
Nirmatrelvir GD_HHV1 Glycoprotein D -6.54 N/A N/A N/A N/A
Nirmatrelvir Modify 02 GD_HHV1 Glycoprotein D -7.23 N/A N/A N/A N/A
Nirmatrelvir GP160_HIV1 Envelope glycoprotein gp160 -6.64 -6.16 -6.17 N/A N/A
Nirmatrelvir Modify 02 GP160_HIV1 Envelope glycoprotein gp160 -6.54 -6.98 -6.88 N/A N/A
Nirmatrelvir GP160_HIV2 Envelope glycoprotein gp160 -6.36 N/A N/A N/A N/A
Nirmatrelvir Modify 02 GP160_HIV2 Envelope glycoprotein gp160 -6.91 N/A N/A N/A N/A
Nirmatrelvir GP_EBOV Envelope glycoprotein -7.37 -7.05 -7.11 33.54% CHEMBL3125897
Nirmatrelvir Modify 02 GP_EBOV Envelope glycoprotein -8.25 -8.23 -7.76 38.36% CHEMBL3125895
Nirmatrelvir GP_LASSJ Pre-glycoprotein polyprotein GP complex -6.12 -6.16 N/A N/A N/A
Nirmatrelvir Modify 02 GP_LASSJ Pre-glycoprotein polyprotein GP complex -6.08 -6.92 N/A N/A N/A
Nirmatrelvir HA_A-H10N7 Hemagglutinin -6.87 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H10N7 Hemagglutinin -7.02 N/A N/A N/A N/A
Nirmatrelvir HA_A-H10N8 Hemagglutinin -6.50 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H10N8 Hemagglutinin -6.68 N/A N/A N/A N/A
Nirmatrelvir HA_A-H13N6 Hemagglutinin -5.98 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H13N6 Hemagglutinin -6.44 N/A N/A N/A N/A
Nirmatrelvir HA_A-H14N6 Hemagglutinin -6.49 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H14N6 Hemagglutinin -7.21 N/A N/A N/A N/A
Nirmatrelvir HA_A-H15N9 Hemagglutinin -6.32 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H15N9 Hemagglutinin -7.06 N/A N/A N/A N/A
Nirmatrelvir HA_A-H17N10 Hemagglutinin -6.07 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H17N10 Hemagglutinin -5.90 N/A N/A N/A N/A
Nirmatrelvir HA_A-H18N11 Hemagglutinin -5.59 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H18N11 Hemagglutinin -6.99 N/A N/A N/A N/A
Nirmatrelvir HA_A-H1N1 Hemagglutinin -6.70 -6.74 N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H1N1 Hemagglutinin -6.74 -6.85 N/A N/A N/A
Nirmatrelvir HA_A-H2N2 Hemagglutinin -6.49 -6.66 N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H2N2 Hemagglutinin -6.50 -6.16 N/A N/A N/A
Nirmatrelvir HA_A-H3N2 Hemagglutinin -6.20 -6.39 -6.16 N/A N/A
Nirmatrelvir Modify 02 HA_A-H3N2 Hemagglutinin -6.95 -6.76 -7.03 N/A N/A
Nirmatrelvir HA_A-H3N8 Hemagglutinin -5.92 -5.77 -5.89 N/A N/A
Nirmatrelvir Modify 02 HA_A-H3N8 Hemagglutinin -6.60 -6.04 -6.78 N/A N/A
Nirmatrelvir HA_A-H5N1 Hemagglutinin -6.59 -6.13 -6.30 N/A N/A
Nirmatrelvir Modify 02 HA_A-H5N1 Hemagglutinin -7.27 -7.44 -6.77 N/A N/A
Nirmatrelvir HA_A-H5N3 Hemagglutinin -6.36 -6.10 N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H5N3 Hemagglutinin -7.16 -6.68 N/A N/A N/A
Nirmatrelvir HA_A-H6N1 Hemagglutinin -6.50 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H6N1 Hemagglutinin -6.68 N/A N/A N/A N/A
Nirmatrelvir HA_A-H6N6 Hemagglutinin -6.41 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H6N6 Hemagglutinin -6.42 N/A N/A N/A N/A
Nirmatrelvir HA_A-H7N2 Hemagglutinin -6.60 -6.46 -6.29 N/A N/A
Nirmatrelvir Modify 02 HA_A-H7N2 Hemagglutinin -6.84 -6.19 -6.66 N/A N/A
Nirmatrelvir HA_A-H7N7 Hemagglutinin -6.12 -6.03 N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H7N7 Hemagglutinin -6.51 -6.80 N/A N/A N/A
Nirmatrelvir HA_A-H7N9 Hemagglutinin -6.01 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_A-H7N9 Hemagglutinin -6.85 N/A N/A N/A N/A
Nirmatrelvir HA_INFB Hemagglutinin -6.36 -6.79 N/A N/A N/A
Nirmatrelvir Modify 02 HA_INFB Hemagglutinin -6.45 -6.61 N/A N/A N/A
Nirmatrelvir HA_INFD Hemagglutinin-esterase-fusion glycoprotein -6.58 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HA_INFD Hemagglutinin-esterase-fusion glycoprotein -7.75 N/A N/A N/A N/A
Nirmatrelvir HE_BCV Hemagglutinin-esterase -6.59 -6.77 N/A N/A N/A
Nirmatrelvir Modify 02 HE_BCV Hemagglutinin-esterase -7.92 -7.51 N/A N/A N/A
Nirmatrelvir HE_HCoV-OC43 Hemagglutinin-esterase -6.07 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HE_HCoV-OC43 Hemagglutinin-esterase -6.77 N/A N/A N/A N/A
Nirmatrelvir HE_MHV Hemagglutinin-esterase -6.21 N/A N/A N/A N/A
Nirmatrelvir Modify 02 HE_MHV Hemagglutinin-esterase -6.72 N/A N/A N/A N/A
Nirmatrelvir IN_HIV1 Gag-Pol polyprotein -5.82 -5.30 N/A N/A N/A
Nirmatrelvir Modify 02 IN_HIV1 Gag-Pol polyprotein -6.41 -6.77 N/A N/A N/A
Nirmatrelvir MD_HKU4 Replicase polyprotein 1ab -9.37 -7.46 -8.86 N/A N/A
Nirmatrelvir Modify 02 MD_HKU4 Replicase polyprotein 1ab -8.18 -9.03 -9.27 N/A N/A
Nirmatrelvir MD_MERs Replicase polyprotein 1a -8.51 -9.04 N/A N/A N/A
Nirmatrelvir Modify 02 MD_MERs Replicase polyprotein 1a -8.30 -8.97 N/A N/A N/A
Nirmatrelvir MEM_9FLAV Core protein -5.33 N/A N/A N/A N/A
Nirmatrelvir Modify 02 MEM_9FLAV Core protein -5.80 N/A N/A N/A N/A
Nirmatrelvir MTASE_SARS2 Methyltransferase -6.32 N/A N/A N/A N/A
Nirmatrelvir MTASE_SARS2 Methyltransferase -7.19 N/A N/A N/A N/A
Nirmatrelvir Modify 02 MTASE_SARS2 Methyltransferase -6.43 N/A N/A N/A N/A
Nirmatrelvir Modify 02 MTASE_SARS2 Methyltransferase -7.81 N/A N/A N/A N/A
Nirmatrelvir MX2_A-H5N1 Matrix protein 2 -0.02 N/A N/A N/A N/A
Nirmatrelvir Modify 02 MX2_A-H5N1 Matrix protein 2 2.58 N/A N/A N/A N/A
Nirmatrelvir MX_9MONO Matrix protein VP40 -8.15 N/A N/A N/A N/A
Nirmatrelvir Modify 02 MX_9MONO Matrix protein VP40 -9.42 N/A N/A N/A N/A
Nirmatrelvir MX_LASSJ RING finger protein Z -5.33 N/A N/A N/A N/A
Nirmatrelvir Modify 02 MX_LASSJ RING finger protein Z -6.28 N/A N/A N/A N/A
Nirmatrelvir NA_A-H11N6 Neuraminidase -7.44 -7.99 -7.64 N/A N/A
Nirmatrelvir Modify 02 NA_A-H11N6 Neuraminidase -9.34 -8.97 -9.18 N/A N/A
Nirmatrelvir NA_A-H11N9 Neuraminidase -6.30 -7.75 -7.98 N/A N/A
Nirmatrelvir Modify 02 NA_A-H11N9 Neuraminidase -6.52 -9.42 -9.23 N/A N/A
Nirmatrelvir NA_A-H12N5 Neuraminidase -6.77 -7.20 -7.46 N/A N/A
Nirmatrelvir Modify 02 NA_A-H12N5 Neuraminidase -8.01 -8.41 -8.57 N/A N/A
Nirmatrelvir NA_A-H13N9 Neuraminidase -6.03 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NA_A-H13N9 Neuraminidase -6.79 N/A N/A N/A N/A
Nirmatrelvir NA_A-H17N10 Neuraminidase -6.89 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NA_A-H17N10 Neuraminidase -7.53 N/A N/A N/A N/A
Nirmatrelvir NA_A-H18N11 Neuraminidase -6.43 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NA_A-H18N11 Neuraminidase -7.55 N/A N/A N/A N/A
Nirmatrelvir NA_A-H1N1 Neuraminidase -7.42 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NA_A-H1N1 Neuraminidase -9.09 N/A N/A N/A N/A
Nirmatrelvir NA_A-H2N2 Neuraminidase -7.43 -7.70 -6.97 N/A N/A
Nirmatrelvir Modify 02 NA_A-H2N2 Neuraminidase -8.86 -9.63 -8.32 N/A N/A
Nirmatrelvir NA_A-H3N2 Ig heavy chain Mem5 -7.38 -6.86 N/A N/A N/A
Nirmatrelvir Modify 02 NA_A-H3N2 Ig heavy chain Mem5 -8.06 -7.67 N/A N/A N/A
Nirmatrelvir NA_A-H3N8 Neuraminidase -8.01 -8.13 -7.24 29.71% CHEMBL674
Nirmatrelvir Modify 02 NA_A-H3N8 Neuraminidase -8.68 -9.15 -9.28 34.83% CHEMBL4285767
Nirmatrelvir NA_A-H5N1 Neuraminidase -7.84 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NA_A-H5N1 Neuraminidase -8.87 N/A N/A N/A N/A
Nirmatrelvir NA_A-H7N9 Neuraminidase -7.38 -7.69 -7.66 N/A N/A
Nirmatrelvir Modify 02 NA_A-H7N9 Neuraminidase -9.00 -9.44 -9.12 N/A N/A
Nirmatrelvir NA_INFB Neuraminidase -6.87 -6.97 N/A 55.10% CHEMBL370047
Nirmatrelvir Modify 02 NA_INFB Neuraminidase -7.96 -8.35 N/A 45.70% CHEMBL362993
Nirmatrelvir NP_9ADNV Nucleoprotein -5.19 -7.17 N/A N/A N/A
Nirmatrelvir Modify 02 NP_9ADNV Nucleoprotein -5.67 -8.05 N/A N/A N/A
Nirmatrelvir NP_A-H1N1 Nucleoprotein -6.37 -6.19 -6.28 N/A N/A
Nirmatrelvir Modify 02 NP_A-H1N1 Nucleoprotein -7.44 -6.93 -7.08 N/A N/A
Nirmatrelvir NP_A-H5N1 Nucleoprotein -6.09 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NP_A-H5N1 Nucleoprotein -7.20 N/A N/A N/A N/A
Nirmatrelvir NP_EBOZM Nucleoprotein -7.14 -5.80 -6.69 N/A N/A
Nirmatrelvir Modify 02 NP_EBOZM Nucleoprotein -6.70 -6.76 -8.24 N/A N/A
Nirmatrelvir NP_HCoV-NL63 Nucleoprotein -6.87 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NP_HCoV-NL63 Nucleoprotein -7.00 N/A N/A N/A N/A
Nirmatrelvir NP_HCoV-OC43 Nucleoprotein -7.26 -7.30 -7.46 15.25% CHEMBL3233481
Nirmatrelvir Modify 02 NP_HCoV-OC43 Nucleoprotein -8.16 -7.86 -7.21 18.71% CHEMBL3233481
Nirmatrelvir NP_INFB Nucleoprotein -6.15 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NP_INFB Nucleoprotein -6.61 N/A N/A N/A N/A
Nirmatrelvir NP_INFD NP -5.38 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NP_INFD NP -5.42 N/A N/A N/A N/A
Nirmatrelvir NP_LASSJ Nucleoprotein -9.16 -8.97 -4.95 N/A N/A
Nirmatrelvir Modify 02 NP_LASSJ Nucleoprotein -10.46 -10.48 -4.72 N/A N/A
Nirmatrelvir NP_SARS Nucleoprotein -6.90 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NP_SARS Nucleoprotein -7.82 N/A N/A N/A N/A
Nirmatrelvir NS1_9CALI NTPase -5.80 -5.72 -6.34 N/A N/A
Nirmatrelvir Modify 02 NS1_9CALI NTPase -6.64 -5.36 -6.83 N/A N/A
Nirmatrelvir NS1_9FLAV Non-structural protein 1 -5.80 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NS1_9FLAV Non-structural protein 1 -6.71 N/A N/A N/A N/A
Nirmatrelvir NS1_DEN1W Genome polyprotein -5.45 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NS1_DEN1W Genome polyprotein -6.09 N/A N/A N/A N/A
Nirmatrelvir NS1_ZIKV Core protein 2.87 -6.03 -7.37 N/A N/A
Nirmatrelvir Modify 02 NS1_ZIKV Core protein 8.64 -6.44 -7.60 N/A N/A
Nirmatrelvir NS2A_9FLAV Core protein -4.39 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NS2A_9FLAV Core protein -4.35 N/A N/A N/A N/A
Nirmatrelvir NS2B_DEN1W Genome polyprotein -6.93 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NS2B_DEN1W Genome polyprotein -7.30 N/A N/A N/A N/A
Nirmatrelvir NS2B_DEN2P Genome polyprotein -7.35 -7.63 N/A N/A N/A
Nirmatrelvir Modify 02 NS2B_DEN2P Genome polyprotein -7.83 -7.57 N/A N/A N/A
Nirmatrelvir NS2B_ZIKV Genome polyprotein -6.46 -6.65 N/A N/A N/A
Nirmatrelvir Modify 02 NS2B_ZIKV Genome polyprotein -7.92 -7.29 N/A N/A N/A
Nirmatrelvir NS2B_ZIKVF Genome polyprotein -7.51 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NS2B_ZIKVF Genome polyprotein -7.97 N/A N/A N/A N/A
Nirmatrelvir NS3_9FLAV Core protein -8.39 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NS3_9FLAV Core protein -8.77 N/A N/A N/A N/A
Nirmatrelvir NS3_DEN4T Genome polyprotein -7.96 -7.55 N/A N/A N/A
Nirmatrelvir Modify 02 NS3_DEN4T Genome polyprotein -9.55 -8.52 N/A N/A N/A
Nirmatrelvir NS3_HCV1A Genome polyprotein -6.26 -6.12 -6.26 60.67% CHEMBL296588
Nirmatrelvir Modify 02 NS3_HCV1A Genome polyprotein -6.86 -6.70 -7.13 45.76% CHEMBL296588
Nirmatrelvir NS3_HCV1B Genome polyprotein -6.27 -7.45 -6.02 50.50% CHEMBL3921185
Nirmatrelvir Modify 02 NS3_HCV1B Genome polyprotein -7.28 -6.93 -6.77 41.43% CHEMBL3927196
Nirmatrelvir NS3_HCV3A Genome polyprotein -6.72 -6.58 -7.07 N/A N/A
Nirmatrelvir Modify 02 NS3_HCV3A Genome polyprotein -7.10 -6.70 -7.66 N/A N/A
Nirmatrelvir NS3_ZIKV Genome polyprotein -8.14 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NS3_ZIKV Genome polyprotein -9.61 N/A N/A N/A N/A
Nirmatrelvir NS5B_HCV1A Genome polyprotein -7.93 -8.39 -8.08 52.00% CHEMBL13443
Nirmatrelvir Modify 02 NS5B_HCV1A Genome polyprotein -8.66 -8.63 -9.36 51.63% CHEMBL68034
Nirmatrelvir NS5B_HCV1B Genome polyprotein -7.79 -7.93 -7.97 20.75% CHEMBL3422106
Nirmatrelvir Modify 02 NS5B_HCV1B Genome polyprotein -8.91 -8.55 -7.95 30.58% CHEMBL3645202
Nirmatrelvir NS5B_HCV2A Genome polyprotein -9.02 -5.57 N/A 34.72% CHEMBL3127326
Nirmatrelvir Modify 02 NS5B_HCV2A Genome polyprotein -9.82 -8.18 N/A 43.87% CHEMBL3127326
Nirmatrelvir NS5_9FLAV Core protein -8.00 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NS5_9FLAV Core protein -8.84 N/A N/A N/A N/A
Nirmatrelvir NS5_DEN3S Genome polyprotein -6.36 -7.11 N/A N/A N/A
Nirmatrelvir Modify 02 NS5_DEN3S Genome polyprotein -8.22 -9.26 N/A N/A N/A
Nirmatrelvir NS5_ZIKV Genome polyprotein -8.24 -5.64 N/A N/A N/A
Nirmatrelvir Modify 02 NS5_ZIKV Genome polyprotein -8.76 -6.12 N/A N/A N/A
Nirmatrelvir NS5_ZIKVF Genome polyprotein -7.36 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NS5_ZIKVF Genome polyprotein -8.44 N/A N/A N/A N/A
Nirmatrelvir NS6_9CALI NTPase -4.79 -5.44 -6.18 N/A N/A
Nirmatrelvir Modify 02 NS6_9CALI NTPase -5.34 -5.97 -6.96 N/A N/A
Nirmatrelvir NSP15_SARS Replicase polyprotein 1ab -7.11 N/A N/A 42.31% CHEMBL2441741
Nirmatrelvir Modify 02 NSP15_SARS Replicase polyprotein 1ab -6.91 N/A N/A 63.36% CHEMBL2441741
Nirmatrelvir NSP15_SARS2 Replicase polyprotein 1ab -6.57 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NSP15_SARS2 Replicase polyprotein 1ab -6.84 N/A N/A N/A N/A
Nirmatrelvir NSP1_INFB Non-structural protein 1 -5.73 -6.05 N/A N/A N/A
Nirmatrelvir Modify 02 NSP1_INFB Non-structural protein 1 -6.70 -6.40 N/A N/A N/A
Nirmatrelvir NSP1_SARS Replicase polyprotein 1ab -5.83 N/A N/A 42.31% CHEMBL2441741
Nirmatrelvir Modify 02 NSP1_SARS Replicase polyprotein 1ab -6.50 N/A N/A 63.36% CHEMBL2441741
Nirmatrelvir NSP3_HCoV-229E Replicase polyprotein 1a -8.42 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NSP3_HCoV-229E Replicase polyprotein 1a -9.15 N/A N/A N/A N/A
Nirmatrelvir NSP3_IBV Replicase polyprotein 1a -6.70 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NSP3_IBV Replicase polyprotein 1a -8.71 N/A N/A N/A N/A
Nirmatrelvir NSP3_MHV Replicase polyprotein 1ab -6.90 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NSP3_MHV Replicase polyprotein 1ab -7.47 N/A N/A N/A N/A
Nirmatrelvir NSP3_SARS2 Replicase polyprotein 1ab -6.88 N/A N/A N/A N/A
Nirmatrelvir Modify 02 NSP3_SARS2 Replicase polyprotein 1ab -7.83 N/A N/A N/A N/A
Nirmatrelvir NSP9_HCoV-229E Replicase polyprotein 1ab -6.85 -6.22 N/A N/A N/A
Nirmatrelvir Modify 02 NSP9_HCoV-229E Replicase polyprotein 1ab -7.84 -6.42 N/A N/A N/A
Nirmatrelvir PA_A-H17N10 Polymerase acidic protein -7.85 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PA_A-H17N10 Polymerase acidic protein -8.40 N/A N/A N/A N/A
Nirmatrelvir PA_A-H1N1 Polymerase acidic protein -8.01 -7.89 -7.62 N/A N/A
Nirmatrelvir Modify 02 PA_A-H1N1 Polymerase acidic protein -8.71 -8.25 -9.02 N/A N/A
Nirmatrelvir PA_A-H5N1 Polymerase acidic protein -8.00 -7.66 -7.53 N/A N/A
Nirmatrelvir Modify 02 PA_A-H5N1 Polymerase acidic protein -9.55 -8.84 -8.62 N/A N/A
Nirmatrelvir PA_INFA Polymerase acidic protein -7.55 -7.78 -7.43 24.03% CHEMBL2040554
Nirmatrelvir Modify 02 PA_INFA Polymerase acidic protein -9.33 -7.77 -8.82 36.96% CHEMBL2040554
Nirmatrelvir PA_INFB Polymerase acidic protein -6.97 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PA_INFB Polymerase acidic protein -8.68 N/A N/A N/A N/A
Nirmatrelvir PB2_A-H3N2 Polymerase basic protein 2 -7.65 -7.85 N/A N/A N/A
Nirmatrelvir Modify 02 PB2_A-H3N2 Polymerase basic protein 2 -8.00 -8.92 N/A N/A N/A
Nirmatrelvir PB2_A-H5N1 Polymerase basic protein 2 -6.80 -7.51 -7.82 N/A N/A
Nirmatrelvir Modify 02 PB2_A-H5N1 Polymerase basic protein 2 -8.56 -7.99 -8.37 N/A N/A
Nirmatrelvir PB2_INFB Polymerase basic protein 2 -6.70 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PB2_INFB Polymerase basic protein 2 -8.53 N/A N/A N/A N/A
Nirmatrelvir PB3_A-H3N2 Polymerase basic protein 2 -7.75 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PB3_A-H3N2 Polymerase basic protein 2 -8.42 N/A N/A N/A N/A
Nirmatrelvir PB4_A-H3N2 Polymerase basic protein 2 -7.68 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PB4_A-H3N2 Polymerase basic protein 2 -8.10 N/A N/A N/A N/A
Nirmatrelvir PLP_SARS Replicase polyprotein 1a -7.55 -7.00 -8.29 42.86% CHEMBL213054
Nirmatrelvir Modify 02 PLP_SARS Replicase polyprotein 1a -9.74 -10.19 -9.61 45.03% CHEMBL213054
Nirmatrelvir PLP_SARS2 papain-like protease -6.84 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PLP_SARS2 papain-like protease -6.70 N/A N/A N/A N/A
Nirmatrelvir PM_9VIRU RNA-directed RNA polymerase L -7.24 -6.94 N/A N/A N/A
Nirmatrelvir Modify 02 PM_9VIRU RNA-directed RNA polymerase L -7.81 -8.75 N/A N/A N/A
Nirmatrelvir PR_FCoV Replicase polyprotein 1ab -7.28 N/A N/A 52.83% CHEMBL4214066
Nirmatrelvir Modify 02 PR_FCoV Replicase polyprotein 1ab -9.14 N/A N/A 48.08% CHEMBL4214471
Nirmatrelvir PR_HCoV-229E Replicase polyprotein 1a -7.35 -7.41 N/A N/A N/A
Nirmatrelvir Modify 02 PR_HCoV-229E Replicase polyprotein 1a -7.60 -7.56 N/A N/A N/A
Nirmatrelvir PR_HCoV-NL63 Replicase polyprotein 1a -4.74 -8.08 N/A N/A N/A
Nirmatrelvir Modify 02 PR_HCoV-NL63 Replicase polyprotein 1a -5.11 -8.44 N/A N/A N/A
Nirmatrelvir PR_HIV1 Gag-Pol polyprotein -6.33 -6.30 -6.29 17.03% CHEMBL492666
Nirmatrelvir Modify 02 PR_HIV1 Gag-Pol polyprotein -6.92 -7.54 -7.08 28.72% CHEMBL492666
Nirmatrelvir PR_HIV2 Gag-Pol polyprotein -6.88 -7.01 N/A N/A N/A
Nirmatrelvir Modify 02 PR_HIV2 Gag-Pol polyprotein -7.79 -7.47 N/A N/A N/A
Nirmatrelvir PR_HKU1 Replicase polyprotein 1a -6.91 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PR_HKU1 Replicase polyprotein 1a -6.25 N/A N/A N/A N/A
Nirmatrelvir PR_HKU4 Replicase polyprotein 1ab -7.66 -7.71 -7.54 N/A N/A
Nirmatrelvir Modify 02 PR_HKU4 Replicase polyprotein 1ab -7.73 -7.75 -7.76 N/A N/A
Nirmatrelvir PR_IBV Replicase polyprotein 1a -7.73 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PR_IBV Replicase polyprotein 1a -8.00 N/A N/A N/A N/A
Nirmatrelvir PR_MERs 3C-like proteinase -6.92 -7.91 N/A N/A N/A
Nirmatrelvir Modify 02 PR_MERs 3C-like proteinase -7.48 -8.09 N/A N/A N/A
Nirmatrelvir PR_PEDV 3C-like proteinase -7.12 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PR_PEDV 3C-like proteinase -7.88 N/A N/A N/A N/A
Nirmatrelvir PR_SARS Replicase polyprotein 1ab -8.10 -7.68 -7.07 42.31% CHEMBL2441741
Nirmatrelvir Modify 02 PR_SARS Replicase polyprotein 1ab -8.18 -7.71 -7.38 63.36% CHEMBL2441741
Nirmatrelvir PR_SARS2 3C-like protease -7.63 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PR_SARS2 3C-like protease -8.61 N/A N/A N/A N/A
Nirmatrelvir PR_TGEV Replicase polyprotein 1a -6.40 N/A N/A N/A N/A
Nirmatrelvir Modify 02 PR_TGEV Replicase polyprotein 1a -7.19 N/A N/A N/A N/A
Nirmatrelvir P_9CALI Norovirus P domain protein -6.90 N/A N/A N/A N/A
Nirmatrelvir Modify 02 P_9CALI Norovirus P domain protein -7.68 N/A N/A N/A N/A
Nirmatrelvir P_NVN68 Capsid protein VP1 -5.79 N/A N/A N/A N/A
Nirmatrelvir Modify 02 P_NVN68 Capsid protein VP1 -5.90 N/A N/A N/A N/A
Nirmatrelvir RDRP_SARS2 RNA-dependent RNA polymerase -6.21 N/A N/A 10.37% CHEMBL4065616
Nirmatrelvir Modify 02 RDRP_SARS2 RNA-dependent RNA polymerase -6.99 N/A N/A 16.56% CHEMBL4065616
Nirmatrelvir RT_HIV1 Gag-Pol polyprotein -8.46 -8.68 -7.39 33.58% CHEMBL4225865
Nirmatrelvir Modify 02 RT_HIV1 Gag-Pol polyprotein -9.80 -10.09 -10.86 47.37% CHEMBL3683703
Nirmatrelvir SPIKE_HCoV-229E Spike glycoprotein -5.10 N/A N/A N/A N/A
Nirmatrelvir Modify 02 SPIKE_HCoV-229E Spike glycoprotein -5.13 N/A N/A N/A N/A
Nirmatrelvir SPIKE_HCoV-NL63 Spike glycoprotein -5.46 N/A N/A N/A N/A
Nirmatrelvir Modify 02 SPIKE_HCoV-NL63 Spike glycoprotein -6.45 N/A N/A N/A N/A
Nirmatrelvir SPIKE_HCoV-OC43 Spike glycoprotein -6.79 N/A N/A N/A N/A
Nirmatrelvir Modify 02 SPIKE_HCoV-OC43 Spike glycoprotein -7.12 N/A N/A N/A N/A
Nirmatrelvir SPIKE_HKU4 Spike glycoprotein -7.52 N/A N/A N/A N/A
Nirmatrelvir Modify 02 SPIKE_HKU4 Spike glycoprotein -6.65 N/A N/A N/A N/A
Nirmatrelvir SPIKE_IBV Spike glycoprotein -6.28 N/A N/A N/A N/A
Nirmatrelvir Modify 02 SPIKE_IBV Spike glycoprotein -6.39 N/A N/A N/A N/A
Nirmatrelvir SPIKE_MERs Spike glycoprotein -6.61 -6.35 -5.98 N/A N/A
Nirmatrelvir Modify 02 SPIKE_MERs Spike glycoprotein -7.09 -6.15 -6.10 N/A N/A
Nirmatrelvir SPIKE_MHV Spike glycoprotein -7.81 N/A N/A N/A N/A
Nirmatrelvir Modify 02 SPIKE_MHV Spike glycoprotein -8.38 N/A N/A N/A N/A
Nirmatrelvir SPIKE_PDCoV Spike protein -6.79 N/A N/A N/A N/A
Nirmatrelvir Modify 02 SPIKE_PDCoV Spike protein -7.38 N/A N/A N/A N/A
Nirmatrelvir SPIKE_SARS Spike glycoprotein -5.72 -6.56 N/A N/A N/A
Nirmatrelvir Modify 02 SPIKE_SARS Spike glycoprotein -6.64 -6.65 N/A N/A N/A
Nirmatrelvir SPIKE_SARS2 Spike glycoprotein -5.43 -5.89 -6.47 N/A N/A
Nirmatrelvir Modify 02 SPIKE_SARS2 Spike glycoprotein -6.64 -6.89 -6.73 N/A N/A
Nirmatrelvir VP1_9CALI Capsid protein -8.05 N/A N/A N/A N/A
Nirmatrelvir Modify 02 VP1_9CALI Capsid protein -8.90 N/A N/A N/A N/A
Nirmatrelvir VP1_NVN68 Capsid protein VP1 -6.42 N/A N/A N/A N/A
Nirmatrelvir Modify 02 VP1_NVN68 Capsid protein VP1 -6.08 N/A N/A N/A N/A
Nirmatrelvir VP24_EBORE Membrane-associated protein VP24 -5.67 N/A N/A N/A N/A
Nirmatrelvir Modify 02 VP24_EBORE Membrane-associated protein VP24 -5.69 N/A N/A N/A N/A
Nirmatrelvir VP24_EBOSU Membrane-associated protein VP24 -5.25 N/A N/A N/A N/A
Nirmatrelvir Modify 02 VP24_EBOSU Membrane-associated protein VP24 -6.04 N/A N/A N/A N/A
Nirmatrelvir VP24_EBOZM Membrane-associated protein VP24 -5.62 N/A N/A N/A N/A
Nirmatrelvir Modify 02 VP24_EBOZM Membrane-associated protein VP24 -6.22 N/A N/A N/A N/A
Nirmatrelvir VP30_9MONO Minor nucleoprotein VP30 -6.09 N/A N/A N/A N/A
Nirmatrelvir Modify 02 VP30_9MONO Minor nucleoprotein VP30 -7.09 N/A N/A N/A N/A
Nirmatrelvir VP30_EBOZ5 Transcriptional activator VP30 -6.52 N/A N/A N/A N/A
Nirmatrelvir Modify 02 VP30_EBOZ5 Transcriptional activator VP30 -8.12 N/A N/A N/A N/A
Nirmatrelvir VP30_EBOZM Transcriptional activator VP30 -6.83 N/A N/A N/A N/A
Nirmatrelvir Modify 02 VP30_EBOZM Transcriptional activator VP30 -7.70 N/A N/A N/A N/A
Nirmatrelvir VP35_EBORR Polymerase cofactor VP35 -6.00 N/A N/A N/A N/A
Nirmatrelvir Modify 02 VP35_EBORR Polymerase cofactor VP35 -7.27 N/A N/A N/A N/A
Nirmatrelvir VP35_EBOZM Polymerase cofactor VP35 -6.25 -6.70 -6.52 N/A N/A
Nirmatrelvir Modify 02 VP35_EBOZM Polymerase cofactor VP35 -6.99 -7.53 -7.26 N/A N/A
Nirmatrelvir VP40_EBOZM Matrix protein VP40 -5.17 -4.92 N/A N/A N/A
Nirmatrelvir Modify 02 VP40_EBOZM Matrix protein VP40 -6.34 -6.37 N/A N/A N/A