| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.87 | -8.27 | -9.27 | 28.57% | CHEMBL1183249 | Inactive | 69.63% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.12 | -8.88 | -8.18 | 21.53% | CHEMBL321190 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.07 | -8.02 | -8.10 | 17.65% | CHEMBL139801 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.88 | -8.78 | -7.79 | 12.97% | CHEMBL103479 | Inactive | 73.37% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.12 | -9.31 | -9.53 | 15.03% | CHEMBL321967 | Inactive | 78.70% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -7.72 | -7.77 | N/A | 73.08% | CHEMBL1909065 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.78 | -9.14 | -8.46 | 73.08% | CHEMBL1909065 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.19 | -9.23 | N/A | 73.08% | CHEMBL1909065 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -10.25 | -8.96 | -9.05 | 20.81% | CHEMBL1632169 | Inactive | 79.40% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -7.57 | -7.97 | -8.23 | 21.94% | CHEMBL3938006 | Inactive | 77.58% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.94 | -8.73 | -8.79 | 73.08% | CHEMBL1909065 | Active | 98.93% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.96 | -8.89 | -8.21 | 30.88% | CHEMBL487192 | Inactive | 65.33% |
| AA1R_HUMAN | adenosine A1 receptor | -7.82 | -9.17 | -4.43 | 28.57% | CHEMBL3956531 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -6.74 | -7.20 | -6.68 | 23.86% | CHEMBL2113418 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -9.27 | -9.00 | -9.26 | 23.43% | CHEMBL464859 | Inactive | 64.22% |
| AA3R_HUMAN | adenosine A3 receptor | -4.82 | -0.31 | -8.80 | 49.23% | CHEMBL1200633 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -10.48 | 9.75 | N/A | 39.33% | CHEMBL353311 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.65 | -8.19 | -8.67 | 39.33% | CHEMBL353311 | Active | 53.23% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -9.68 | -8.90 | -7.88 | 37.76% | CHEMBL480464 | Active | 56.75% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.49 | -6.57 | N/A | 37.76% | CHEMBL480464 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -9.68 | -8.79 | -7.70 | 32.03% | CHEMBL1201027 | Active | 71.43% |
| ACTHR_HUMAN | melanocortin 2 receptor | -9.74 | -9.80 | -9.64 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -9.60 | -10.10 | -9.29 | 73.08% | CHEMBL1909065 | Active | 82.05% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -2.86 | -5.59 | 0.09 | 73.08% | CHEMBL1909065 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -10.40 | -5.69 | -4.74 | 73.08% | CHEMBL1909065 | Active | 62.30% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 2.03 | 2.94 | 1.45 | 73.08% | CHEMBL1909065 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.30 | -7.79 | -9.11 | 25.38% | CHEMBL1085395 | Inactive | 75.14% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.92 | -7.75 | -9.99 | 25.38% | CHEMBL1085395 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -9.68 | -6.96 | -8.67 | 25.38% | CHEMBL1085395 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -8.33 | -9.08 | -8.30 | 16.98% | CHEMBL3350599 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.73 | -9.37 | -9.01 | 20.12% | CHEMBL2372276 | Inactive | 86.76% |
| CALCR_HUMAN | calcitonin receptor | -8.87 | -8.85 | -8.26 | 16.85% | CHEMBL2369895 | Inactive | 98.93% |
| CCKAR_HUMAN | cholecystokinin A receptor | -9.43 | -9.19 | -8.72 | 19.78% | CHEMBL168182 | Inactive | 72.50% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.00 | -9.28 | -8.94 | 22.86% | CHEMBL344324 | Inactive | 81.12% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.38 | -8.63 | -8.12 | 29.84% | CHEMBL1684700 | Inactive | 77.13% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -8.38 | -8.46 | -8.37 | 19.71% | CHEMBL64391 | Inactive | 79.63% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.47 | -8.53 | -8.33 | 27.89% | CHEMBL278383 | Inactive | 94.81% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.03 | -8.90 | -9.30 | 19.26% | CHEMBL22776 | Inactive | 87.15% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.96 | -8.47 | -7.13 | 40.40% | CHEMBL175247 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -8.24 | -9.83 | N/A | 39.39% | CHEMBL1800732 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.08 | N/A | N/A | 14.29% | CHEMBL139 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -7.93 | -8.34 | -7.94 | 18.30% | CHEMBL3645131 | Inactive | 67.15% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.57 | -8.28 | -8.39 | 22.29% | CHEMBL3956593 | Inactive | 96.71% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -9.04 | -7.81 | -8.13 | 29.13% | CHEMBL1221944 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -8.36 | -9.64 | -9.09 | 19.46% | CHEMBL85409 | Inactive | 58.64% |
| DRD2_HUMAN | dopamine receptor D2 | -8.36 | N/A | N/A | 73.08% | CHEMBL1909065 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.61 | N/A | N/A | 73.08% | CHEMBL1909065 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -8.97 | -9.07 | N/A | 25.51% | CHEMBL2443008 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -8.75 | -8.88 | -6.85 | 15.96% | CHEMBL1258223 | Inactive | 81.09% |
| EDNRA_HUMAN | endothelin receptor type A | -7.78 | -8.40 | -8.01 | 29.20% | CHEMBL64424 | Inactive | 52.83% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 9.14 | 7.04 | 21.79 | 10.76% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.96 | -8.74 | -7.34 | 21.59% | CHEMBL433028 | Inactive | 76.40% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.68 | -7.37 | -3.14 | 32.71% | CHEMBL254372 | Inactive | 99.99% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | 1.35 | 3.28 | 2.74 | 43.01% | CHEMBL275079 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | 0.02 | 0.66 | -1.84 | 43.01% | CHEMBL275079 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 2.44 | 3.66 | 3.20 | 19.20% | CHEMBL578988 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.77 | 0.40 | -2.15 | 27.91% | CHEMBL90501 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -4.28 | -2.87 | -4.39 | 43.01% | CHEMBL275079 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -4.73 | 0.03 | -2.88 | 22.90% | CHEMBL432038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 4.66 | 8.62 | 8.78 | 26.19% | CHEMBL280563 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -0.28 | N/A | N/A | 21.13% | CHEMBL1278112 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.05 | -9.40 | -8.94 | 19.05% | CHEMBL1626 | Active | 81.49% |
| HRH3_HUMAN | histamine receptor H3 | -7.23 | -9.42 | -9.84 | 25.98% | CHEMBL20338 | Inactive | 67.28% |
| HRH4_HUMAN | histamine receptor H4 | -8.79 | -9.23 | -8.87 | 25.98% | CHEMBL20338 | Inactive | 67.54% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.54 | -7.57 | -7.55 | 21.05% | CHEMBL213956 | Inactive | 82.14% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.94 | -7.54 | -7.78 | 21.82% | CHEMBL1519347 | Inactive | 95.84% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.58 | -5.73 | -5.04 | 21.95% | CHEMBL1221512 | Inactive | 71.67% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.33 | -7.42 | -8.06 | 21.05% | CHEMBL213752 | Inactive | 74.93% |
| NK1R_HUMAN | tachykinin receptor 1 | -9.67 | -7.66 | -8.29 | 36.50% | CHEMBL282618 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -8.83 | -8.94 | -8.96 | 32.09% | CHEMBL225264 | Inactive | 94.56% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -9.11 | -9.27 | -9.74 | 20.56% | CHEMBL1989216 | Inactive | 73.21% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.58 | -8.69 | -8.72 | 17.88% | CHEMBL1672379 | Inactive | 84.03% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -9.32 | -10.16 | -8.98 | 16.67% | CHEMBL230333 | Inactive | 66.64% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.44 | -9.33 | -10.18 | 34.71% | CHEMBL1223998 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.63 | -8.62 | -8.33 | 23.53% | CHEMBL3099726 | Inactive | 95.69% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -9.02 | -9.22 | -9.40 | 22.17% | CHEMBL3099723 | Inactive | 99.16% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.04 | -8.35 | -8.52 | 22.17% | CHEMBL3099727 | Inactive | 83.51% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.69 | -7.40 | -7.64 | 34.97% | CHEMBL3597083 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -10.14 | -8.73 | -8.03 | 77.78% | CHEMBL560302 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.57 | -7.74 | -8.46 | 39.68% | CHEMBL3219937 | Inactive | 75.35% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.83 | -8.40 | -7.89 | 24.34% | CHEMBL3326232 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.14 | -7.53 | -8.12 | 100.00% | CHEMBL514432 | Active | 99.99% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -8.15 | -9.91 | -8.50 | 24.81% | CHEMBL1335190 | Inactive | 69.44% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -9.92 | -10.90 | -10.14 | 17.39% | CHEMBL3945037 | Inactive | 90.18% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -7.70 | -8.52 | -8.94 | 18.26% | CHEMBL396270 | Inactive | 95.99% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.20 | -7.83 | -8.38 | 16.83% | CHEMBL3884667 | N/A | N/A |