| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -6.12 | -5.75 | -5.82 | 48.21% | CHEMBL146942 | Active | 53.72% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -6.57 | -6.29 | -6.07 | 48.21% | CHEMBL146942 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -6.25 | -6.41 | -6.18 | 43.75% | CHEMBL73281 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -6.30 | -6.41 | -6.59 | 24.00% | CHEMBL39 | Inactive | 60.65% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -6.39 | -6.81 | -6.58 | 24.49% | CHEMBL3617549 | Inactive | 76.99% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -6.71 | -6.43 | N/A | 70.00% | CHEMBL445747 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -6.90 | -6.87 | -6.95 | 70.00% | CHEMBL445747 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -6.96 | -6.84 | N/A | 70.00% | CHEMBL445747 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -6.60 | -6.82 | -6.41 | 27.27% | CHEMBL80015 | Inactive | 60.61% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -6.67 | -6.36 | -6.39 | 34.09% | CHEMBL161507 | Inactive | 52.75% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -6.17 | -6.00 | -6.05 | 48.21% | CHEMBL146942 | Inactive | 56.56% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -6.37 | -6.67 | -6.54 | 53.06% | CHEMBL443757 | Active | 90.84% |
| AA1R_HUMAN | adenosine A1 receptor | -6.48 | -6.74 | -6.85 | 29.07% | CHEMBL1544 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -7.02 | -6.85 | -6.54 | 26.87% | CHEMBL86771 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -6.01 | -6.21 | -5.60 | 21.21% | CHEMBL67949 | Inactive | 63.00% |
| AA3R_HUMAN | adenosine A3 receptor | -7.54 | -7.43 | -6.07 | 42.11% | CHEMBL701 | Active | 66.38% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -6.88 | -7.56 | N/A | 49.15% | CHEMBL3084679 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -6.21 | -5.97 | -6.88 | 49.15% | CHEMBL3084679 | Active | 70.92% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -5.72 | -6.50 | -6.98 | 50.88% | CHEMBL3084397 | Active | 51.52% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.04 | -6.78 | N/A | 47.54% | CHEMBL1490 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -6.52 | -6.37 | -6.73 | 47.54% | CHEMBL1490 | Inactive | 57.33% |
| ACTHR_HUMAN | melanocortin 2 receptor | -8.31 | -8.17 | -7.24 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -6.13 | -6.32 | -5.89 | 45.61% | CHEMBL21731 | Active | 79.31% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -7.04 | -6.98 | -6.47 | 58.54% | CHEMBL61006 | Active | 87.69% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -7.34 | -7.20 | -7.25 | 45.61% | CHEMBL21731 | Active | 64.55% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -6.26 | -6.25 | -5.93 | 45.76% | CHEMBL17157 | Active | 73.22% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -6.27 | -6.51 | -6.37 | 36.23% | CHEMBL566777 | Inactive | 56.85% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.50 | -7.17 | -6.74 | 40.62% | CHEMBL1800960 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -7.11 | -7.34 | -7.00 | 36.00% | CHEMBL12994 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -6.79 | -6.64 | -6.46 | 24.75% | CHEMBL128416 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -6.75 | -7.08 | -6.95 | 27.54% | CHEMBL121565 | Inactive | 84.86% |
| CALCR_HUMAN | calcitonin receptor | -5.96 | -5.73 | -5.65 | 18.75% | CHEMBL2369895 | Inactive | 61.21% |
| CCKAR_HUMAN | cholecystokinin A receptor | -6.64 | -6.46 | -7.22 | 20.49% | CHEMBL105619 | Inactive | 92.66% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.24 | -7.48 | -5.81 | 40.30% | CHEMBL140270 | Inactive | 98.77% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -6.12 | -6.08 | -5.67 | 41.67% | CHEMBL3753178 | Inactive | 98.28% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -5.71 | -5.96 | -6.59 | 22.40% | CHEMBL208249 | Inactive | 90.56% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -6.37 | -6.67 | -6.23 | 45.76% | CHEMBL17157 | Inactive | 96.21% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -7.47 | -7.97 | -7.44 | 32.95% | CHEMBL22776 | Inactive | 92.84% |
| CNR1_HUMAN | cannabinoid receptor 1 | -6.34 | -6.54 | -7.23 | 57.69% | CHEMBL233182 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -7.13 | -7.24 | N/A | 76.32% | CHEMBL264412 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.61 | N/A | N/A | 31.34% | CHEMBL191413 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -7.06 | -5.22 | -5.12 | 31.34% | CHEMBL191413 | Inactive | 64.62% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -6.85 | -6.94 | -6.88 | 31.65% | CHEMBL495752 | Inactive | 98.90% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.24 | -5.25 | -6.06 | 25.40% | CHEMBL2170299 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -6.60 | -6.57 | -6.21 | 45.61% | CHEMBL21731 | Active | 51.17% |
| DRD2_HUMAN | dopamine receptor D2 | -6.27 | N/A | N/A | 48.39% | CHEMBL130665 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -6.82 | N/A | N/A | 53.85% | CHEMBL93234 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -6.41 | -6.26 | N/A | 42.42% | CHEMBL1258270 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -6.69 | -6.87 | -6.91 | 45.61% | CHEMBL21731 | Inactive | 76.86% |
| EDNRA_HUMAN | endothelin receptor type A | -5.13 | -6.03 | -5.49 | 40.30% | CHEMBL290026 | Inactive | 91.18% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -6.95 | -7.06 | -7.52 | 21.30% | CHEMBL2391908 | Inactive | 92.62% |
| GASR_HUMAN | cholecystokinin B receptor | -6.11 | -6.44 | -5.31 | 26.44% | CHEMBL38874 | Inactive | 92.40% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.01 | -7.02 | -6.84 | 42.03% | CHEMBL254372 | Inactive | 63.03% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -7.52 | -7.82 | -7.56 | 51.79% | CHEMBL2112585 | Active | 75.03% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -8.05 | -8.31 | -7.95 | 51.79% | CHEMBL2112584 | Active | 77.48% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -6.46 | -6.59 | -6.58 | 18.05% | CHEMBL3797923 | Inactive | 94.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.09 | -8.14 | -8.05 | 46.15% | CHEMBL1682795 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -7.54 | -7.74 | -7.58 | 14.81% | CHEMBL280563 | Inactive | 98.44% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.73 | -6.74 | -7.02 | 32.95% | CHEMBL432038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -6.46 | -6.99 | -6.72 | 32.95% | CHEMBL432038 | Inactive | 98.49% |
| HRH1_HUMAN | histamine receptor H1 | -7.68 | N/A | N/A | 53.33% | CHEMBL594138 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -8.15 | -6.78 | -7.05 | 45.61% | CHEMBL21731 | Active | 84.49% |
| HRH3_HUMAN | histamine receptor H3 | -6.64 | -5.64 | -5.79 | 54.72% | CHEMBL1270058 | Active | 97.32% |
| HRH4_HUMAN | histamine receptor H4 | -6.11 | -5.97 | -6.12 | 40.62% | CHEMBL1934066 | Active | 61.21% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.24 | -7.02 | -6.03 | 25.49% | CHEMBL272099 | Inactive | 77.79% |
| MC4R_HUMAN | melanocortin 4 receptor | -5.44 | -5.51 | -5.97 | 49.06% | CHEMBL194464 | Active | 55.19% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.61 | -6.78 | -5.61 | 26.26% | CHEMBL3958082 | Inactive | 67.06% |
| MSHR_HUMAN | melanocortin 1 receptor | -6.97 | -6.34 | -6.89 | 25.25% | CHEMBL1091631 | Inactive | 65.25% |
| NK1R_HUMAN | tachykinin receptor 1 | -6.32 | -6.59 | -5.88 | 52.63% | CHEMBL143813 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -6.31 | -6.18 | -6.32 | 45.76% | CHEMBL17157 | Inactive | 98.46% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -5.76 | -5.77 | -5.54 | 19.08% | CHEMBL1940539 | Inactive | 93.40% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -6.00 | -5.71 | -5.52 | 30.23% | CHEMBL3361424 | Inactive | 61.91% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -6.08 | -7.32 | -5.99 | 26.09% | CHEMBL3086828 | Inactive | 85.25% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -6.87 | -6.67 | -6.34 | 39.66% | CHEMBL3559801 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -6.11 | -5.72 | -5.61 | 39.66% | CHEMBL3559801 | Active | 60.54% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -6.18 | -5.88 | -5.41 | 39.66% | CHEMBL3559801 | Active | 96.09% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -5.65 | -5.69 | -5.72 | 39.66% | CHEMBL3559801 | Inactive | 76.55% |
| OPRD_HUMAN | opioid receptor delta 1 | -6.13 | -5.70 | -6.19 | 47.37% | CHEMBL202327 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -6.92 | -6.83 | -6.24 | 47.46% | CHEMBL2260849 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -6.55 | -5.86 | -6.02 | 53.70% | CHEMBL3937167 | Inactive | 74.62% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -5.90 | -5.85 | -6.07 | 53.70% | CHEMBL3937167 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -7.26 | -7.43 | -7.43 | 38.16% | CHEMBL297624 | Active | 51.20% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -6.92 | -6.31 | -6.57 | 58.33% | CHEMBL19393 | Active | 78.08% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -6.65 | -6.86 | -6.60 | 27.72% | CHEMBL3891546 | Inactive | 92.76% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -5.78 | -5.71 | -6.51 | 29.03% | CHEMBL1807275 | Inactive | 96.57% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -6.90 | -5.72 | -6.86 | 18.47% | CHEMBL483749 | N/A | N/A |