Drug combination for HCV treatment #387 Output Download CSV

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  The docking scores are in the AutoDock Vina metric.
L: Brequinar
NA_A-H3N2

Docking Scores:
-9.48 -7.99
Similarity Score:
N/A
Best Match:
N/A

L: Niclosamide
NA_A-H3N2

Docking Scores:
-7.14 -6.73
Similarity Score:
N/A
Best Match:
N/A

L: Sofosbuvir
NA_A-H3N2

Docking Scores:
-7.73 -7.27
Similarity Score:
N/A
Best Match:
N/A

L: Brequinar
NA_A-H3N8

Docking Scores:
-8.03 -8.85 -8.08
Similarity Score:
17.29%
Best Match:
CHEMBL4288395

L: Niclosamide
NA_A-H3N8

Docking Scores:
-6.51 -7.38 -6.84
Similarity Score:
23.12%
Best Match:
CHEMBL4292576

L: Sofosbuvir
NA_A-H3N8

Docking Scores:
-8.27 -8.22 -8.43
Similarity Score:
19.67%
Best Match:
CHEMBL4288395

L: Brequinar
NA_A-H5N1

Docking Scores:
-8.30
Similarity Score:
N/A
Best Match:
N/A

L: Niclosamide
NA_A-H5N1

Docking Scores:
-7.26
Similarity Score:
N/A
Best Match:
N/A

L: Sofosbuvir
NA_A-H5N1

Docking Scores:
-8.38
Similarity Score:
N/A
Best Match:
N/A

L: Brequinar
NA_A-H7N9

Docking Scores:
-8.72 -8.10 -7.86
Similarity Score:
N/A
Best Match:
N/A

L: Niclosamide
NA_A-H7N9

Docking Scores:
-6.73 -7.20 -7.10
Similarity Score:
N/A
Best Match:
N/A

L: Sofosbuvir
NA_A-H7N9

Docking Scores:
-7.61 -7.71 -7.83
Similarity Score:
N/A
Best Match:
N/A

L: Brequinar
NA_INFB

Docking Scores:
-8.22 -8.25
Similarity Score:
16.51%
Best Match:
CHEMBL4175983

L: Niclosamide
NA_INFB

Docking Scores:
-6.99 -7.23
Similarity Score:
28.89%
Best Match:
CHEMBL4161935

L: Sofosbuvir
NA_INFB

Docking Scores:
-7.93 -7.72
Similarity Score:
21.67%
Best Match:
CHEMBL4128362

L: Brequinar
NP_9ADNV

Docking Scores:
-6.05 -10.02
Similarity Score:
N/A
Best Match:
N/A

L: Niclosamide
NP_9ADNV

Docking Scores:
-4.65 -8.02
Similarity Score:
N/A
Best Match:
N/A

L: Sofosbuvir
NP_9ADNV

Docking Scores:
-5.09 -7.70
Similarity Score:
N/A
Best Match:
N/A

L: Brequinar
NP_A-H1N1

Docking Scores:
-7.79 -8.15 -7.73
Similarity Score:
N/A
Best Match:
N/A

L: Niclosamide
NP_A-H1N1

Docking Scores:
-6.05 -6.41 -7.76
Similarity Score:
N/A
Best Match:
N/A