| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -11.05 | -9.94 | -9.92 | 46.19% | CHEMBL1242904 | Active | 73.03% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -11.81 | -11.65 | -11.02 | 46.19% | CHEMBL1242904 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -11.77 | -10.70 | -10.65 | 46.19% | CHEMBL1242904 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -10.70 | -8.38 | -10.46 | 33.70% | CHEMBL267615 | Inactive | 58.67% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -10.78 | -11.28 | -10.60 | 33.67% | CHEMBL497963 | Inactive | 59.85% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -12.02 | -11.25 | N/A | 45.05% | CHEMBL1222553 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -11.85 | -10.97 | -10.86 | 44.83% | CHEMBL1222624 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -11.49 | -10.94 | N/A | 45.05% | CHEMBL1222554 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -11.93 | -12.08 | -10.15 | 37.07% | CHEMBL2402898 | Active | 51.32% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -9.76 | -9.54 | -10.25 | 42.64% | CHEMBL435814 | Active | 74.58% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -12.04 | -10.48 | -11.68 | 44.21% | CHEMBL3409251 | Active | 87.82% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -11.28 | -10.82 | -10.79 | 45.36% | CHEMBL476862 | Active | 69.22% |
| AA1R_HUMAN | adenosine A1 receptor | -9.90 | -11.22 | -6.98 | 46.60% | CHEMBL3317571 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -10.68 | -10.89 | -9.65 | 53.23% | CHEMBL2312988 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -10.72 | -11.12 | -10.29 | 40.60% | CHEMBL260692 | Inactive | 63.01% |
| AA3R_HUMAN | adenosine A3 receptor | -1.18 | -4.19 | 0.18 | 41.38% | CHEMBL4062581 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -9.29 | 33.28 | N/A | 41.75% | CHEMBL603713 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -11.64 | -10.56 | -7.24 | 37.93% | CHEMBL296419 | Active | 63.55% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -10.87 | -12.54 | -11.04 | 40.30% | CHEMBL1836644 | Active | 60.90% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.42 | -8.17 | N/A | 39.50% | CHEMBL3808485 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -10.78 | -9.74 | -11.43 | 37.93% | CHEMBL296419 | Active | 82.12% |
| ACTHR_HUMAN | melanocortin 2 receptor | -11.97 | -10.95 | -8.54 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -10.81 | -9.85 | -10.97 | 38.92% | CHEMBL3809093 | Active | 61.22% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | 12.32 | 15.20 | 18.65 | 36.67% | CHEMBL218730 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -12.71 | -12.13 | -11.63 | 36.67% | CHEMBL218730 | Inactive | 55.49% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 31.22 | 32.47 | 8.88 | 37.93% | CHEMBL296419 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -10.98 | -11.78 | -11.74 | 45.89% | CHEMBL467298 | Inactive | 66.01% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -10.16 | -9.78 | -11.94 | 40.54% | CHEMBL461463 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -10.80 | -12.12 | -10.81 | 40.29% | CHEMBL467103 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -10.00 | -10.59 | -11.64 | 38.53% | CHEMBL40381 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -11.85 | -12.21 | -11.72 | 44.68% | CHEMBL544623 | Active | 63.85% |
| CALCR_HUMAN | calcitonin receptor | -9.67 | -10.41 | -9.78 | 27.03% | CHEMBL2369897 | Inactive | 97.68% |
| CCKAR_HUMAN | cholecystokinin A receptor | -9.45 | -8.96 | -9.48 | 43.64% | CHEMBL479030 | Inactive | 54.90% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -10.50 | -9.02 | -9.45 | 36.62% | CHEMBL1784685 | Active | 54.41% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -9.06 | -9.50 | -9.33 | 37.14% | CHEMBL2018534 | Inactive | 53.00% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -8.89 | -9.28 | -10.12 | 36.36% | CHEMBL2435852 | Active | 58.88% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -9.86 | -9.35 | -9.47 | 37.50% | CHEMBL499109 | Inactive | 52.73% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -10.11 | -11.33 | -12.17 | 41.78% | CHEMBL1214532 | Active | 72.44% |
| CNR1_HUMAN | cannabinoid receptor 1 | -9.47 | -10.37 | -9.45 | 42.50% | CHEMBL1224370 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -12.83 | -12.61 | N/A | 46.43% | CHEMBL471992 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -0.43 | N/A | N/A | 27.19% | CHEMBL3609013 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -11.07 | -9.12 | -8.85 | 36.62% | CHEMBL1784685 | Inactive | 75.52% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -11.53 | -10.86 | -11.55 | 45.98% | CHEMBL1077807 | Active | 66.33% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -10.82 | -8.87 | -9.37 | 36.70% | CHEMBL583443 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -10.75 | -9.74 | -12.33 | 42.08% | CHEMBL3671296 | Active | 79.59% |
| DRD2_HUMAN | dopamine receptor D2 | -11.18 | N/A | N/A | 50.00% | CHEMBL111054 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -9.74 | N/A | N/A | 52.87% | CHEMBL313692 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -12.03 | -12.32 | N/A | 40.74% | CHEMBL210551 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -9.41 | -11.79 | -8.30 | 36.49% | CHEMBL4087909 | Inactive | 82.79% |
| EDNRA_HUMAN | endothelin receptor type A | -9.60 | -8.83 | -9.40 | 40.25% | CHEMBL3753134 | Active | 50.44% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 24.82 | 13.24 | ? | ? | ? | ? | ? |
| GASR_HUMAN | cholecystokinin B receptor | -10.06 | -8.41 | -8.07 | 44.55% | CHEMBL37312 | Active | 51.75% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -11.12 | -10.74 | -1.96 | 39.15% | CHEMBL3968177 | Inactive | 99.99% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | 26.86 | 27.69 | 28.17 | 41.67% | CHEMBL594236 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | 11.49 | 1.75 | -5.90 | 37.80% | CHEMBL3401177 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 27.04 | 17.68 | 18.98 | 39.42% | CHEMBL3560922 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -8.10 | 4.54 | -1.81 | 48.85% | CHEMBL207733 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | 0.24 | 3.92 | 4.58 | 30.87% | CHEMBL1585091 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | 0.78 | 2.26 | 2.40 | 39.42% | CHEMBL3560922 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 15.79 | 13.24 | 22.36 | 39.42% | CHEMBL3560922 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -6.51 | N/A | N/A | 46.80% | CHEMBL3952802 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -11.29 | -10.46 | -9.93 | 36.73% | CHEMBL1086105 | Active | 98.47% |
| HRH3_HUMAN | histamine receptor H3 | -9.96 | -11.21 | -10.22 | 59.34% | CHEMBL497355 | Active | 86.72% |
| HRH4_HUMAN | histamine receptor H4 | -10.29 | -10.43 | -8.94 | 49.16% | CHEMBL220933 | Inactive | 68.39% |
| MC3R_HUMAN | melanocortin 3 receptor | -11.10 | -11.17 | -10.42 | 37.67% | CHEMBL392092 | Active | 56.52% |
| MC4R_HUMAN | melanocortin 4 receptor | -9.34 | -8.86 | -8.67 | 45.20% | CHEMBL1699140 | Inactive | 57.89% |
| MC5R_HUMAN | melanocortin 5 receptor | -8.27 | -9.95 | -7.60 | 33.88% | CHEMBL503229 | Inactive | 71.87% |
| MSHR_HUMAN | melanocortin 1 receptor | -9.23 | -9.75 | -10.00 | 34.62% | CHEMBL2112918 | Inactive | 51.34% |
| NK1R_HUMAN | tachykinin receptor 1 | -9.92 | -10.44 | -10.37 | 41.12% | CHEMBL47070 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -10.48 | -11.07 | -10.77 | 37.93% | CHEMBL296419 | Active | 67.93% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -9.98 | -9.81 | -10.10 | 33.47% | CHEMBL1981304 | Inactive | 51.43% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -10.42 | -9.31 | -9.56 | 30.47% | CHEMBL376756 | Inactive | 58.94% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -11.23 | -11.66 | -11.09 | 34.23% | CHEMBL3086836 | Active | 90.75% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -11.23 | -10.43 | -10.15 | 44.08% | CHEMBL346243 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -9.51 | -10.94 | -9.89 | 33.06% | CHEMBL438935 | Inactive | 59.37% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -10.72 | -11.39 | -10.88 | 30.14% | CHEMBL2371909 | Inactive | 99.60% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -9.17 | -9.18 | -9.69 | 36.17% | CHEMBL417225 | Active | 63.90% |
| OPRD_HUMAN | opioid receptor delta 1 | -9.16 | -8.61 | -8.83 | 39.74% | CHEMBL561138 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -11.79 | -9.89 | -10.89 | 37.95% | CHEMBL480425 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -10.61 | -9.42 | -8.95 | 44.33% | CHEMBL258781 | Active | 63.36% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -9.87 | -9.70 | -9.91 | 44.33% | CHEMBL258781 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -9.84 | -9.68 | -9.58 | 43.84% | CHEMBL37602 | Active | 67.38% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -12.14 | -11.91 | -11.39 | 33.52% | CHEMBL1549077 | Inactive | 65.87% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -10.68 | -11.65 | -9.69 | 38.25% | CHEMBL1357440 | Active | 72.39% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -10.60 | -10.23 | -10.88 | 38.54% | CHEMBL330510 | Active | 74.72% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -10.76 | -10.02 | -10.85 | 36.62% | CHEMBL1784685 | N/A | N/A |