| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.85 | -6.25 | -4.72 | 31.41% | CHEMBL93186 | Inactive | 81.08% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.48 | -8.35 | -8.57 | 29.41% | CHEMBL82488 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.15 | -8.33 | -9.11 | 29.41% | CHEMBL82488 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -9.14 | -7.19 | -7.90 | 17.76% | CHEMBL103479 | Inactive | 77.65% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -10.03 | -10.90 | -8.86 | 24.34% | CHEMBL177258 | Inactive | 70.32% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -10.77 | -2.90 | N/A | 42.59% | CHEMBL3676853 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -10.25 | -9.35 | -7.42 | 35.88% | CHEMBL1909065 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.82 | -7.89 | N/A | 35.88% | CHEMBL1909065 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -7.78 | -7.71 | -7.53 | 27.01% | CHEMBL198226 | Inactive | 72.37% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -7.19 | -8.68 | -9.33 | 23.49% | CHEMBL161507 | Active | 64.19% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.13 | -9.00 | -7.51 | 35.88% | CHEMBL1909065 | Active | 52.84% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -10.54 | -10.05 | -8.99 | 36.42% | CHEMBL487192 | Active | 52.87% |
| AA1R_HUMAN | adenosine A1 receptor | -9.44 | -11.43 | 2.91 | 30.89% | CHEMBL146549 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -5.83 | -7.41 | -5.53 | 26.32% | CHEMBL1950653 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -9.63 | -8.47 | -9.77 | 30.22% | CHEMBL4072891 | Inactive | 66.17% |
| AA3R_HUMAN | adenosine A3 receptor | 5.24 | 14.36 | 1.19 | 29.51% | CHEMBL1200633 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | 1.91 | 35.14 | N/A | 38.30% | CHEMBL74736 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -8.38 | -9.01 | 1.70 | 38.30% | CHEMBL74736 | Inactive | 99.99% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -9.67 | -7.10 | -8.71 | 37.01% | CHEMBL1201335 | Active | 52.23% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -2.17 | -6.27 | N/A | 36.88% | CHEMBL2377269 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -6.00 | -7.63 | -6.82 | 36.77% | CHEMBL1201027 | Active | 73.03% |
| ACTHR_HUMAN | melanocortin 2 receptor | -8.87 | -10.11 | -7.49 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.53 | -8.79 | -8.18 | 35.88% | CHEMBL1909065 | Inactive | 56.27% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | 22.32 | 17.70 | 27.01 | 35.88% | CHEMBL1909065 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -7.26 | 12.17 | 6.59 | 35.88% | CHEMBL1909065 | Inactive | 99.99% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 26.40 | 31.33 | 32.61 | 35.88% | CHEMBL1909065 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.92 | -8.46 | -9.75 | 32.05% | CHEMBL1085395 | Inactive | 55.57% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.35 | -7.47 | -8.27 | 33.70% | CHEMBL1431082 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -10.15 | -7.97 | -10.34 | 32.05% | CHEMBL1085395 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -10.02 | -10.18 | -9.43 | 22.17% | CHEMBL214592 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -7.75 | -7.83 | -9.33 | 18.81% | CHEMBL2372276 | Inactive | 88.26% |
| CALCR_HUMAN | calcitonin receptor | -8.86 | -9.89 | -9.93 | 20.31% | CHEMBL2369886 | Inactive | 97.66% |
| CCKAR_HUMAN | cholecystokinin A receptor | -9.79 | -9.66 | -9.54 | 21.96% | CHEMBL168182 | Inactive | 59.43% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -9.76 | -9.44 | -8.04 | 27.32% | CHEMBL69659 | Inactive | 74.72% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -9.85 | -9.21 | -8.84 | 31.03% | CHEMBL3263259 | Inactive | 64.96% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.66 | -7.18 | -7.46 | 20.66% | CHEMBL64391 | Inactive | 78.47% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -10.09 | -9.56 | -9.85 | 34.12% | CHEMBL504250 | Inactive | 53.53% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.99 | -10.50 | -9.99 | 25.60% | CHEMBL3401686 | Inactive | 77.94% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.07 | -7.46 | -6.90 | 32.67% | CHEMBL1923760 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -7.28 | -10.84 | N/A | 36.30% | CHEMBL1923778 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | 15.23 | N/A | N/A | 25.10% | CHEMBL246733 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.68 | -9.32 | -9.56 | 25.10% | CHEMBL246733 | Inactive | 64.01% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -10.97 | -10.21 | -10.77 | 27.46% | CHEMBL3956593 | Inactive | 55.59% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -10.43 | -8.39 | -9.71 | 24.68% | CHEMBL3923006 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -8.08 | -8.94 | -10.50 | 29.24% | CHEMBL291143 | Inactive | 56.69% |
| DRD2_HUMAN | dopamine receptor D2 | -9.57 | N/A | N/A | 42.59% | CHEMBL3676853 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -9.69 | N/A | N/A | 42.59% | CHEMBL3676853 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -6.40 | -5.95 | N/A | 32.74% | CHEMBL3318835 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -4.35 | -6.35 | 4.43 | 21.40% | CHEMBL1258223 | Inactive | 99.99% |
| EDNRA_HUMAN | endothelin receptor type A | -9.51 | -9.33 | -9.33 | 35.71% | CHEMBL103190 | Inactive | 60.81% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 28.02 | 25.02 | 40.22 | 15.34% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -9.64 | -8.20 | -8.54 | 26.15% | CHEMBL103276 | Inactive | 66.27% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -8.50 | -5.60 | 8.40 | 36.03% | CHEMBL254372 | Inactive | 99.99% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | 34.56 | 30.43 | 33.31 | 42.03% | CHEMBL3955458 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | 18.12 | 20.08 | 13.08 | 42.03% | CHEMBL3955458 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 28.17 | 34.86 | 27.65 | 20.42% | CHEMBL2063423 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | 15.58 | 24.47 | 20.25 | 24.54% | CHEMBL92162 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | 12.85 | 13.37 | 7.83 | 32.33% | CHEMBL275079 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | 24.49 | 27.63 | 26.50 | 26.71% | CHEMBL432038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 19.82 | 25.30 | 26.02 | 26.71% | CHEMBL432038 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | 16.73 | N/A | N/A | 27.93% | CHEMBL328356 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.92 | -9.29 | -9.57 | 25.97% | CHEMBL422931 | Active | 86.07% |
| HRH3_HUMAN | histamine receptor H3 | -7.12 | -7.93 | -9.85 | 32.73% | CHEMBL514217 | Inactive | 61.61% |
| HRH4_HUMAN | histamine receptor H4 | -7.99 | -7.39 | -9.49 | 30.12% | CHEMBL105803 | Inactive | 50.36% |
| MC3R_HUMAN | melanocortin 3 receptor | -8.41 | -8.61 | -7.37 | 26.24% | CHEMBL380437 | Inactive | 74.16% |
| MC4R_HUMAN | melanocortin 4 receptor | -8.87 | -8.75 | -8.98 | 26.24% | CHEMBL380437 | Inactive | 79.00% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.34 | -6.18 | -0.31 | 26.56% | CHEMBL1221512 | Inactive | 99.99% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.72 | -6.66 | -9.87 | 26.24% | CHEMBL380437 | Active | 60.61% |
| NK1R_HUMAN | tachykinin receptor 1 | -11.03 | -9.02 | -9.57 | 41.96% | CHEMBL378984 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -10.62 | -10.42 | -10.70 | 36.36% | CHEMBL3545252 | Active | 67.07% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -9.42 | -10.50 | -10.60 | 21.61% | CHEMBL1968661 | Inactive | 59.44% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -10.33 | -9.86 | -10.03 | 18.18% | CHEMBL1672379 | Inactive | 61.76% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -10.43 | -9.52 | -6.27 | 22.45% | CHEMBL1800088 | Active | 57.01% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -11.45 | -10.91 | -10.52 | 27.88% | CHEMBL1223993 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -10.59 | -9.75 | -10.06 | 24.90% | CHEMBL3099726 | Inactive | 77.12% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -11.12 | -11.14 | -9.12 | 24.60% | CHEMBL3099721 | Inactive | 98.44% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -9.14 | -9.44 | -8.92 | 30.11% | CHEMBL570633 | Inactive | 66.15% |
| OPRD_HUMAN | opioid receptor delta 1 | -9.32 | -9.03 | -9.42 | 66.20% | CHEMBL3330670 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -12.37 | -9.61 | -8.69 | 86.32% | CHEMBL2381586 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -10.17 | -9.06 | -8.64 | 80.34% | CHEMBL498116 | Active | 98.47% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.97 | -8.95 | -9.43 | 39.80% | CHEMBL3581762 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -9.20 | -8.90 | -8.88 | 46.48% | CHEMBL2304167 | Active | 65.99% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -3.71 | -9.35 | -8.78 | 26.46% | CHEMBL1420390 | Inactive | 99.99% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -12.77 | -12.63 | -12.04 | 20.21% | CHEMBL3945037 | Active | 53.80% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -8.78 | -9.45 | -9.13 | 25.10% | CHEMBL389581 | Inactive | 79.26% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -10.83 | -10.53 | -10.59 | 18.22% | CHEMBL3884667 | N/A | N/A |