| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.76 | -8.51 | -7.95 | 61.18% | CHEMBL1254829 | Active | 83.82% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.21 | -9.28 | -9.18 | 54.32% | CHEMBL140416 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.88 | -8.73 | -8.07 | 54.32% | CHEMBL140416 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -9.19 | -8.89 | -9.26 | 28.46% | CHEMBL2391541 | Inactive | 67.38% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -8.88 | -8.60 | -9.28 | 34.75% | CHEMBL184994 | Inactive | 57.35% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.95 | -9.47 | N/A | 53.47% | CHEMBL3260337 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.42 | -8.62 | -9.11 | 44.76% | CHEMBL3260334 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.56 | -9.58 | N/A | 50.47% | CHEMBL1091104 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -9.90 | -9.62 | -9.42 | 42.15% | CHEMBL182590 | Active | 63.20% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.93 | -8.35 | -8.64 | 43.93% | CHEMBL126667 | Inactive | 51.34% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.48 | -7.70 | -9.07 | 50.00% | CHEMBL455332 | Active | 79.96% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.16 | -8.28 | -9.17 | 44.59% | CHEMBL3581255 | Active | 72.32% |
| AA1R_HUMAN | adenosine A1 receptor | -9.30 | -8.30 | -8.96 | 38.27% | CHEMBL3763972 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -8.83 | -9.12 | -9.80 | 38.27% | CHEMBL3763972 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.31 | -8.83 | -8.16 | 33.15% | CHEMBL199826 | Inactive | 68.02% |
| AA3R_HUMAN | adenosine A3 receptor | -8.24 | -8.74 | -9.80 | 40.00% | CHEMBL27673 | Inactive | 67.29% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.97 | -6.03 | N/A | 44.66% | CHEMBL221753 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.34 | -8.01 | -9.20 | 47.12% | CHEMBL2151158 | Active | 63.06% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.30 | -9.69 | -10.05 | 45.00% | CHEMBL521986 | Active | 72.75% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.28 | -8.83 | N/A | 44.66% | CHEMBL221753 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -9.58 | -9.90 | -9.80 | 44.66% | CHEMBL221753 | Active | 69.06% |
| ACTHR_HUMAN | melanocortin 2 receptor | -10.33 | -10.71 | -8.25 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.26 | -8.82 | -8.01 | 61.18% | CHEMBL1254829 | Active | 77.68% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -7.29 | -8.37 | -3.97 | 46.23% | CHEMBL4091137 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -10.06 | -9.73 | -10.22 | 51.04% | CHEMBL2432051 | Active | 65.50% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -6.41 | -3.77 | -1.64 | 53.26% | CHEMBL2432056 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -8.87 | -8.87 | -9.20 | 42.98% | CHEMBL299175 | Inactive | 51.01% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -7.85 | -9.38 | -8.49 | 47.47% | CHEMBL3799593 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -9.14 | -10.15 | -9.06 | 47.24% | CHEMBL105475 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -9.36 | -9.22 | -8.76 | 48.23% | CHEMBL155987 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.36 | -10.62 | -10.27 | 31.91% | CHEMBL210662 | Inactive | 65.07% |
| CALCR_HUMAN | calcitonin receptor | -8.29 | -8.14 | -8.76 | 18.03% | CHEMBL2369895 | Inactive | 98.34% |
| CCKAR_HUMAN | cholecystokinin A receptor | -7.87 | -8.23 | -8.17 | 25.71% | CHEMBL505225 | Inactive | 96.57% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.54 | -7.43 | -7.89 | 44.25% | CHEMBL234622 | Inactive | 75.68% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.72 | -8.00 | -7.87 | 39.34% | CHEMBL272331 | Inactive | 54.03% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.61 | -8.21 | -9.14 | 54.64% | CHEMBL1623307 | Active | 51.91% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -9.10 | -8.67 | -8.69 | 48.70% | CHEMBL233638 | Inactive | 78.15% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -7.72 | -8.88 | -9.11 | 37.68% | CHEMBL128151 | Inactive | 89.75% |
| CNR1_HUMAN | cannabinoid receptor 1 | -9.29 | -10.08 | -9.69 | 58.77% | CHEMBL260284 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -9.25 | -9.93 | N/A | 50.00% | CHEMBL3410829 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.41 | N/A | N/A | 29.89% | CHEMBL490688 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -9.02 | -7.93 | -6.72 | 33.82% | CHEMBL3645131 | Inactive | 58.81% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.46 | -9.05 | -9.28 | 50.40% | CHEMBL3952475 | Inactive | 65.78% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.15 | -7.65 | -7.78 | 37.37% | CHEMBL3781301 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.26 | -8.36 | -8.44 | 47.47% | CHEMBL3797876 | Active | 79.51% |
| DRD2_HUMAN | dopamine receptor D2 | -8.52 | N/A | N/A | 58.02% | CHEMBL101285 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.07 | N/A | N/A | 58.02% | CHEMBL101285 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -9.51 | -9.23 | N/A | 58.02% | CHEMBL101285 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -9.31 | -9.49 | -8.96 | 41.67% | CHEMBL2334891 | Active | 80.19% |
| EDNRA_HUMAN | endothelin receptor type A | -7.73 | -7.86 | -8.20 | 47.01% | CHEMBL48652 | Active | 54.56% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -1.93 | -4.78 | 2.69 | 26.62% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.65 | -8.31 | -6.48 | 25.48% | CHEMBL30756 | Inactive | 82.05% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -8.46 | -9.83 | -8.73 | 25.88% | CHEMBL3634432 | Inactive | 66.21% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -5.73 | -4.55 | -4.80 | 54.72% | CHEMBL485175 | Active | 61.18% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -5.48 | -8.10 | -8.60 | 37.01% | CHEMBL4081453 | Inactive | 95.08% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -1.03 | -1.39 | -1.39 | 33.58% | CHEMBL2023460 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -9.31 | -8.83 | -8.76 | 61.70% | CHEMBL2151818 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -7.02 | -8.15 | -5.62 | 20.65% | CHEMBL4101970 | Inactive | 89.32% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -4.21 | -3.22 | -5.59 | 25.75% | CHEMBL3560922 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -4.75 | -4.40 | -3.07 | 25.75% | CHEMBL3560922 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -10.68 | N/A | N/A | 44.17% | CHEMBL402143 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.84 | -8.02 | -8.33 | 46.09% | CHEMBL3735289 | Active | 98.23% |
| HRH3_HUMAN | histamine receptor H3 | -9.12 | -7.51 | -7.85 | 60.23% | CHEMBL193978 | Active | 81.03% |
| HRH4_HUMAN | histamine receptor H4 | -8.51 | -8.12 | -8.37 | 38.26% | CHEMBL1934062 | Inactive | 60.82% |
| MC3R_HUMAN | melanocortin 3 receptor | -8.75 | -8.54 | -7.93 | 31.65% | CHEMBL257759 | Inactive | 69.74% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.42 | -7.49 | -7.73 | 66.67% | CHEMBL1501300 | Active | 79.96% |
| MC5R_HUMAN | melanocortin 5 receptor | -7.29 | -9.94 | -7.65 | 35.29% | CHEMBL3932950 | Inactive | 66.01% |
| MSHR_HUMAN | melanocortin 1 receptor | -9.30 | -8.50 | -10.10 | 33.92% | CHEMBL1682208 | Inactive | 62.05% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.85 | -9.48 | -8.55 | 49.56% | CHEMBL138056 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -8.89 | -8.67 | -8.79 | 49.46% | CHEMBL4111499 | Inactive | 83.87% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -8.44 | -7.05 | -7.59 | 27.43% | CHEMBL1940538 | Inactive | 88.63% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.28 | -8.48 | -8.62 | 30.61% | CHEMBL2208334 | Inactive | 71.79% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -8.69 | -9.74 | -8.43 | 27.22% | CHEMBL469695 | Inactive | 69.20% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.24 | -9.11 | -8.03 | 38.35% | CHEMBL2397291 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.08 | -8.53 | -7.56 | 35.61% | CHEMBL2030193 | Inactive | 94.19% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.17 | -8.46 | -8.13 | 29.90% | CHEMBL3559801 | Inactive | 72.45% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.21 | -7.79 | -8.36 | 43.31% | CHEMBL445613 | Active | 50.59% |
| OPRD_HUMAN | opioid receptor delta 1 | -8.46 | -7.05 | -7.49 | 44.35% | CHEMBL611163 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -8.86 | -8.80 | -9.23 | 51.35% | CHEMBL384895 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -9.71 | -8.41 | -8.68 | 51.35% | CHEMBL384895 | Active | 66.19% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.64 | -7.62 | -7.77 | 45.19% | CHEMBL388122 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -7.84 | -8.18 | -9.27 | 37.61% | CHEMBL297624 | Active | 50.78% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -9.40 | -8.89 | -8.96 | 52.34% | CHEMBL1391510 | Inactive | 57.38% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -9.26 | -9.70 | -9.83 | 36.67% | CHEMBL1705547 | Inactive | 88.74% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -8.12 | -7.81 | -9.39 | 38.52% | CHEMBL1084326 | Inactive | 87.43% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -9.11 | -8.55 | -8.18 | 22.04% | CHEMBL520349 | N/A | N/A |