| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -6.82 | -7.05 | -6.80 | 39.13% | CHEMBL3769446 | Active | 59.82% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -6.95 | -7.25 | -7.17 | 38.89% | CHEMBL73281 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -7.05 | -7.16 | -5.97 | 38.89% | CHEMBL73281 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -6.82 | -6.57 | -6.82 | 22.22% | CHEMBL39 | Inactive | 61.19% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -6.76 | -7.76 | -6.93 | 24.30% | CHEMBL318110 | Inactive | 74.81% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -7.38 | -7.27 | N/A | 50.00% | CHEMBL104088 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -7.22 | -8.14 | -7.29 | 52.00% | CHEMBL475643 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.00 | -8.13 | N/A | 52.00% | CHEMBL475643 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -8.03 | -7.98 | -7.30 | 25.00% | CHEMBL309655 | Inactive | 80.89% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -7.24 | -7.05 | -6.97 | 30.53% | CHEMBL161507 | Inactive | 62.98% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -6.65 | -6.71 | -7.25 | 39.39% | CHEMBL17157 | Inactive | 50.53% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -6.95 | -7.71 | -6.75 | 42.11% | CHEMBL443757 | Inactive | 57.08% |
| AA1R_HUMAN | adenosine A1 receptor | -7.23 | -7.03 | -7.92 | 31.46% | CHEMBL1544 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -7.12 | -7.39 | -7.43 | 26.39% | CHEMBL86771 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -7.21 | -7.27 | -6.80 | 28.33% | CHEMBL2113345 | Inactive | 57.74% |
| AA3R_HUMAN | adenosine A3 receptor | -8.05 | -8.09 | -7.02 | 50.00% | CHEMBL701 | Active | 70.42% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.76 | -7.22 | N/A | 51.52% | CHEMBL2164888 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -7.18 | -6.57 | -7.75 | 50.75% | CHEMBL1191560 | Inactive | 53.37% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -6.70 | -7.44 | -7.82 | 50.75% | CHEMBL1191560 | Active | 54.60% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.86 | -7.83 | N/A | 50.00% | CHEMBL2377392 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -7.33 | -7.42 | -7.95 | 48.57% | CHEMBL2107687 | Active | 85.92% |
| ACTHR_HUMAN | melanocortin 2 receptor | -8.01 | -7.90 | -7.87 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -6.63 | -6.85 | -6.99 | 42.35% | CHEMBL41677 | Active | 57.19% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -7.33 | -7.61 | -6.44 | 54.35% | CHEMBL61006 | Active | 93.33% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -8.31 | -8.28 | -8.42 | 41.27% | CHEMBL1076211 | Active | 73.13% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -4.92 | -4.32 | -4.52 | 39.39% | CHEMBL17157 | Inactive | 68.39% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -7.02 | -7.40 | -7.53 | 42.67% | CHEMBL408694 | Active | 69.45% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.74 | -8.09 | -7.38 | 37.33% | CHEMBL1332942 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -7.29 | -8.34 | -7.06 | 42.67% | CHEMBL408694 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -7.17 | -7.19 | -6.89 | 30.69% | CHEMBL128416 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -7.38 | -7.59 | -7.37 | 30.56% | CHEMBL121565 | Inactive | 84.08% |
| CALCR_HUMAN | calcitonin receptor | -6.40 | -6.58 | -6.53 | 18.79% | CHEMBL2369895 | Inactive | 93.37% |
| CCKAR_HUMAN | cholecystokinin A receptor | -6.47 | -6.60 | -7.78 | 23.84% | CHEMBL249560 | Inactive | 94.40% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.52 | -8.00 | -6.43 | 40.45% | CHEMBL356718 | Inactive | 97.94% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -6.88 | -6.85 | -6.44 | 37.97% | CHEMBL3754764 | Inactive | 98.37% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -6.43 | -6.60 | -8.09 | 19.67% | CHEMBL397845 | Inactive | 85.00% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -6.71 | -6.69 | -6.85 | 45.57% | CHEMBL100336 | Inactive | 95.44% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -6.90 | -7.49 | -8.13 | 33.70% | CHEMBL22776 | Inactive | 96.38% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.43 | -7.51 | -7.98 | 51.61% | CHEMBL391380 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -7.61 | -7.51 | N/A | 55.32% | CHEMBL264412 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.43 | N/A | N/A | 44.62% | CHEMBL191413 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -7.23 | -6.36 | -5.85 | 44.62% | CHEMBL191413 | Active | 62.54% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -7.86 | -7.71 | -7.68 | 29.91% | CHEMBL458422 | Inactive | 97.88% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.11 | -5.46 | -6.38 | 25.00% | CHEMBL2180085 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -7.30 | -6.61 | -7.22 | 34.52% | CHEMBL305660 | Inactive | 73.70% |
| DRD2_HUMAN | dopamine receptor D2 | -7.04 | N/A | N/A | 38.89% | CHEMBL1258270 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -7.07 | N/A | N/A | 39.71% | CHEMBL1765637 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -7.20 | -7.21 | N/A | 38.89% | CHEMBL1258270 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -7.94 | -7.63 | -7.47 | 32.95% | CHEMBL54 | Inactive | 82.35% |
| EDNRA_HUMAN | endothelin receptor type A | -5.92 | -6.43 | -6.41 | 38.89% | CHEMBL290026 | Inactive | 80.32% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -6.52 | -6.46 | -7.83 | 19.13% | CHEMBL2391908 | Inactive | 91.33% |
| GASR_HUMAN | cholecystokinin B receptor | -6.50 | -6.90 | -6.01 | 28.89% | CHEMBL38874 | Inactive | 91.59% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.73 | -8.06 | -8.18 | 36.84% | CHEMBL254372 | Inactive | 69.71% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -7.64 | -8.43 | -8.06 | 44.44% | CHEMBL2112585 | Active | 69.17% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -9.47 | -9.02 | -9.18 | 44.44% | CHEMBL2112584 | Active | 52.30% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -6.54 | -6.60 | -6.46 | 22.14% | CHEMBL3901929 | Inactive | 94.04% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.45 | -8.06 | -8.11 | 42.65% | CHEMBL1682794 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -8.14 | -8.04 | -8.26 | 17.24% | CHEMBL280563 | Inactive | 97.74% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.90 | -6.67 | -7.03 | 29.47% | CHEMBL432038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -6.07 | -6.97 | -6.87 | 46.38% | CHEMBL143210 | Inactive | 97.98% |
| HRH1_HUMAN | histamine receptor H1 | -8.05 | N/A | N/A | 54.55% | CHEMBL914 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -8.42 | -6.70 | -8.56 | 37.65% | CHEMBL1627 | Active | 93.25% |
| HRH3_HUMAN | histamine receptor H3 | -7.26 | -6.71 | -6.69 | 51.56% | CHEMBL3427233 | Active | 78.55% |
| HRH4_HUMAN | histamine receptor H4 | -6.98 | -7.06 | -6.91 | 37.04% | CHEMBL489493 | Active | 73.01% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.39 | -7.21 | -6.33 | 27.62% | CHEMBL272099 | Inactive | 74.74% |
| MC4R_HUMAN | melanocortin 4 receptor | -5.94 | -5.99 | -6.56 | 33.33% | CHEMBL371896 | Inactive | 79.47% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.21 | -6.93 | -6.18 | 26.17% | CHEMBL185862 | Inactive | 57.35% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.71 | -6.93 | -7.43 | 27.45% | CHEMBL1091631 | Inactive | 75.49% |
| NK1R_HUMAN | tachykinin receptor 1 | -6.92 | -7.25 | -6.57 | 43.75% | CHEMBL56811 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -7.11 | -7.78 | -6.89 | 39.39% | CHEMBL17157 | Inactive | 98.80% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -6.41 | -6.11 | -6.54 | 20.95% | CHEMBL2314288 | Inactive | 95.46% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -6.83 | -6.35 | -6.45 | 27.55% | CHEMBL2208317 | Inactive | 87.44% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -6.84 | -7.49 | -6.61 | 29.79% | CHEMBL3086828 | Inactive | 80.29% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -7.70 | -7.47 | -7.37 | 32.22% | CHEMBL558133 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -6.88 | -6.27 | -6.08 | 31.82% | CHEMBL3559801 | Inactive | 61.05% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -6.77 | -6.94 | -6.50 | 31.82% | CHEMBL3559801 | Active | 90.59% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -6.43 | -6.44 | -6.37 | 31.82% | CHEMBL3559801 | Inactive | 89.35% |
| OPRD_HUMAN | opioid receptor delta 1 | -6.63 | -6.50 | -6.30 | 38.46% | CHEMBL201038 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -7.68 | -7.49 | -6.96 | 42.86% | CHEMBL651 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -6.72 | -6.38 | -7.00 | 48.57% | CHEMBL607 | Inactive | 87.55% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -6.35 | -6.38 | -6.89 | 41.86% | CHEMBL186300 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -7.76 | -7.73 | -7.62 | 29.07% | CHEMBL297624 | Inactive | 73.36% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -7.88 | -7.11 | -7.19 | 50.00% | CHEMBL19393 | Active | 90.67% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -7.49 | -7.65 | -7.45 | 24.32% | CHEMBL3969230 | Inactive | 95.72% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -6.54 | -6.23 | -7.88 | 35.23% | CHEMBL1807264 | Inactive | 93.20% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -6.91 | -6.67 | -6.79 | 18.56% | CHEMBL3884667 | N/A | N/A |