| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | |||||
| HU-580 | 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.07 | -7.43 | -7.85 | 38.57% | CHEMBL158210 | Inactive | 69.69% |
| CBDA | 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -7.76 | -8.22 | -7.87 | 40.00% | CHEMBL146942 | Inactive | 50.89% |
| HU-580 | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.49 | -8.41 | -8.39 | 36.97% | CHEMBL146942 | N/A | N/A |
| CBDA | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.73 | -9.00 | -8.43 | 40.00% | CHEMBL146942 | N/A | N/A |
| HU-580 | 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.66 | -8.28 | -7.38 | 32.09% | CHEMBL26998 | N/A | N/A |
| CBDA | 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.80 | -8.34 | -8.29 | 33.33% | CHEMBL26998 | N/A | N/A |
| HU-580 | 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.12 | -7.96 | -7.98 | 25.79% | CHEMBL22744 | Inactive | 68.81% |
| CBDA | 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.15 | -8.31 | -7.97 | 27.07% | CHEMBL22744 | Inactive | 65.63% |
| HU-580 | 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -8.66 | -8.71 | -8.37 | 24.04% | CHEMBL3616488 | Inactive | 67.16% |
| CBDA | 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -8.55 | -8.84 | -8.66 | 24.57% | CHEMBL3616488 | Inactive | 66.90% |
| HU-580 | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.14 | -8.80 | N/A | 35.90% | CHEMBL3104523 | N/A | N/A |
| CBDA | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.16 | -8.95 | N/A | 38.10% | CHEMBL3104523 | N/A | N/A |
| HU-580 | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.24 | -8.51 | -8.34 | 34.67% | CHEMBL502620 | N/A | N/A |
| CBDA | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.43 | -8.36 | -8.65 | 32.85% | CHEMBL3818056 | N/A | N/A |
| HU-580 | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.45 | -9.15 | N/A | 37.66% | CHEMBL542436 | N/A | N/A |
| CBDA | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.84 | -8.76 | N/A | 35.33% | CHEMBL542436 | N/A | N/A |
| HU-580 | 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -7.97 | -8.25 | -7.45 | 31.25% | CHEMBL585567 | Inactive | 76.87% |
| CBDA | 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -8.54 | -8.65 | -8.47 | 32.07% | CHEMBL585567 | Inactive | 82.00% |
| HU-580 | 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -9.01 | -7.45 | -7.25 | 47.76% | CHEMBL161507 | Inactive | 60.54% |
| CBDA | 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.64 | -7.39 | -8.57 | 42.11% | CHEMBL161507 | Inactive | 50.59% |
| HU-580 | 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -6.95 | -7.27 | -8.58 | 36.97% | CHEMBL146942 | Active | 65.06% |
| CBDA | 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -7.53 | -7.74 | -8.52 | 40.00% | CHEMBL146942 | Active | 70.40% |
| HU-580 | 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.27 | -8.33 | -8.53 | 36.97% | CHEMBL146942 | Inactive | 53.00% |
| CBDA | 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.63 | -8.02 | -8.15 | 40.00% | CHEMBL146942 | Active | 53.13% |
| HU-580 | AA1R_HUMAN | adenosine A1 receptor | -8.02 | -8.36 | -6.49 | 28.57% | CHEMBL383134 | N/A | N/A |
| CBDA | AA1R_HUMAN | adenosine A1 receptor | -8.42 | -8.26 | -7.75 | 28.57% | CHEMBL383134 | N/A | N/A |
| HU-580 | AA2AR_HUMAN | adenosine A2a receptor | -8.12 | -7.67 | -8.75 | 28.57% | CHEMBL383134 | N/A | N/A |
| CBDA | AA2AR_HUMAN | adenosine A2a receptor | -8.62 | -7.95 | -8.93 | 28.57% | CHEMBL383134 | N/A | N/A |
| HU-580 | AA2BR_HUMAN | adenosine A2b receptor | -8.14 | -8.17 | -8.24 | 24.14% | CHEMBL339936 | Inactive | 71.81% |
| CBDA | AA2BR_HUMAN | adenosine A2b receptor | -8.04 | -7.92 | -8.13 | 23.35% | CHEMBL589251 | Inactive | 70.58% |
| HU-580 | AA3R_HUMAN | adenosine A3 receptor | -8.19 | -5.83 | -7.93 | 32.09% | CHEMBL56 | Active | 50.23% |
| CBDA | AA3R_HUMAN | adenosine A3 receptor | -8.82 | -6.03 | -8.63 | 33.33% | CHEMBL56 | Inactive | 66.53% |
| HU-580 | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.27 | -3.26 | N/A | 36.23% | CHEMBL3085495 | N/A | N/A |
| CBDA | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.99 | -3.14 | N/A | 37.69% | CHEMBL3085495 | N/A | N/A |
| HU-580 | ACM2_HUMAN | cholinergic receptor muscarinic 2 | -8.51 | -8.83 | -8.78 | 36.23% | CHEMBL3085495 | Inactive | 61.18% |
| CBDA | ACM2_HUMAN | cholinergic receptor muscarinic 2 | -8.94 | -8.32 | -9.78 | 37.69% | CHEMBL3085495 | Active | 51.67% |
| HU-580 | ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.24 | -9.13 | -9.58 | 36.23% | CHEMBL3085495 | Active | 54.63% |
| CBDA | ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.80 | -8.71 | -8.96 | 37.69% | CHEMBL3085495 | Inactive | 52.69% |
| HU-580 | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.66 | -6.66 | N/A | 36.23% | CHEMBL3085495 | N/A | N/A |
| CBDA | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.26 | -7.64 | N/A | 37.69% | CHEMBL3085495 | N/A | N/A |
| HU-580 | ACM5_HUMAN | cholinergic receptor muscarinic 5 | -8.88 | -8.96 | -8.46 | 30.77% | CHEMBL305660 | Active | 61.66% |
| CBDA | ACM5_HUMAN | cholinergic receptor muscarinic 5 | -8.92 | -9.16 | -9.68 | 29.41% | CHEMBL170221 | Active | 65.85% |
| HU-580 | ACTHR_HUMAN | melanocortin 2 receptor | -9.10 | -8.67 | -8.56 | N/A | N/A | N/A | N/A |
| CBDA | ACTHR_HUMAN | melanocortin 2 receptor | -9.02 | -9.38 | -8.43 | N/A | N/A | N/A | N/A |
| HU-580 | ADA1D_HUMAN | adrenoceptor alpha 1D | -8.23 | -7.58 | -8.24 | 36.42% | CHEMBL98168 | Inactive | 68.14% |
| CBDA | ADA1D_HUMAN | adrenoceptor alpha 1D | -8.31 | -7.60 | -7.90 | 38.35% | CHEMBL429 | Inactive | 66.58% |
| HU-580 | ADA2A_HUMAN | adrenoceptor alpha 2A | -2.49 | -2.97 | -0.45 | 33.33% | CHEMBL317912 | Inactive | 99.99% |
| CBDA | ADA2A_HUMAN | adrenoceptor alpha 2A | -3.56 | -4.75 | -2.28 | 35.37% | CHEMBL317912 | Inactive | 99.99% |
| HU-580 | ADA2B_HUMAN | adrenoceptor alpha 2B | -9.24 | -9.49 | -7.39 | 30.77% | CHEMBL305660 | Inactive | 58.35% |
| CBDA | ADA2B_HUMAN | adrenoceptor alpha 2B | -9.21 | -9.76 | -7.42 | 31.67% | CHEMBL1242950 | Inactive | 56.41% |
| HU-580 | ADA2C_HUMAN | adrenoceptor alpha 2C | -2.91 | -0.35 | 0.65 | 32.67% | CHEMBL14638 | Inactive | 99.99% |
| CBDA | ADA2C_HUMAN | adrenoceptor alpha 2C | -2.77 | 0.19 | 0.52 | 33.80% | CHEMBL14638 | Inactive | 99.99% |
| HU-580 | ADRB1_HUMAN | adrenoceptor beta 1 | -8.73 | -8.00 | -8.32 | 35.92% | CHEMBL429 | Inactive | 59.61% |
| CBDA | ADRB1_HUMAN | adrenoceptor beta 1 | -9.29 | -8.36 | -8.68 | 38.35% | CHEMBL429 | Inactive | 59.26% |
| HU-580 | ADRB2_HUMAN | adrenoceptor beta 2 | -7.85 | -8.68 | -8.49 | 37.24% | CHEMBL1082607 | N/A | N/A |
| CBDA | ADRB2_HUMAN | adrenoceptor beta 2 | -7.77 | -9.45 | -8.71 | 38.69% | CHEMBL1082607 | N/A | N/A |
| HU-580 | ADRB3_HUMAN | adrenoceptor beta 3 | -8.92 | -7.99 | -9.11 | 35.85% | CHEMBL498519 | N/A | N/A |
| CBDA | ADRB3_HUMAN | adrenoceptor beta 3 | -9.13 | -8.48 | -8.85 | 36.55% | CHEMBL1201237 | N/A | N/A |
| HU-580 | AGTR2_HUMAN | angiotensin II receptor type 2 | -8.31 | -8.88 | -7.92 | 30.46% | CHEMBL156100 | N/A | N/A |
| CBDA | AGTR2_HUMAN | angiotensin II receptor type 2 | -8.08 | -7.98 | -7.93 | 28.93% | CHEMBL154057 | N/A | N/A |
| HU-580 | BKRB2_HUMAN | bradykinin receptor B2 | -8.84 | -8.62 | -8.49 | 24.02% | CHEMBL140383 | Inactive | 89.22% |
| CBDA | BKRB2_HUMAN | bradykinin receptor B2 | -8.82 | -8.90 | -8.95 | 21.80% | CHEMBL483749 | Inactive | 88.11% |
| HU-580 | CALCR_HUMAN | calcitonin receptor | -6.61 | -7.85 | -8.02 | 21.89% | CHEMBL2369897 | Inactive | 98.16% |
| CBDA | CALCR_HUMAN | calcitonin receptor | -7.10 | -8.06 | -8.06 | 22.77% | CHEMBL2369897 | Inactive | 98.49% |
| HU-580 | CCKAR_HUMAN | cholecystokinin A receptor | -8.55 | -7.63 | -8.67 | 24.60% | CHEMBL2372623 | Inactive | 96.35% |
| CBDA | CCKAR_HUMAN | cholecystokinin A receptor | -8.43 | -7.37 | -8.54 | 25.00% | CHEMBL2372623 | Inactive | 96.88% |
| HU-580 | CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.76 | -6.62 | -7.45 | 40.14% | CHEMBL3138187 | Inactive | 93.36% |
| CBDA | CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.81 | -7.74 | -7.71 | 42.75% | CHEMBL3138187 | Inactive | 82.32% |
| HU-580 | CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.51 | -8.57 | -7.73 | 44.27% | CHEMBL3754155 | Inactive | 63.65% |
| CBDA | CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.29 | -8.13 | -7.78 | 47.54% | CHEMBL3754155 | Inactive | 64.25% |
| HU-580 | CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.37 | -7.95 | -7.75 | 26.76% | CHEMBL1618631 | Inactive | 74.99% |
| CBDA | CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.50 | -7.64 | -7.20 | 24.82% | CHEMBL1623307 | Inactive | 77.89% |
| HU-580 | CCR5_HUMAN | C-C motif chemokine receptor 5 | -7.58 | -7.83 | -7.68 | 35.86% | CHEMBL103268 | Inactive | 97.69% |
| CBDA | CCR5_HUMAN | C-C motif chemokine receptor 5 | -7.36 | -7.83 | -7.62 | 38.24% | CHEMBL103268 | Inactive | 97.38% |
| HU-580 | CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.50 | -8.71 | -8.94 | 38.46% | CHEMBL276879 | Inactive | 94.12% |
| CBDA | CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.45 | -8.30 | -9.03 | 39.47% | CHEMBL11625 | Inactive | 94.72% |
| HU-580 | CNR1_HUMAN | cannabinoid receptor 1 | -6.68 | -8.69 | -10.08 | 63.96% | CHEMBL394305 | N/A | N/A |
| CBDA | CNR1_HUMAN | cannabinoid receptor 1 | -6.92 | -8.43 | -9.77 | 69.61% | CHEMBL394305 | N/A | N/A |
| HU-580 | CNR2_HUMAN | cannabinoid receptor 2 | -9.05 | -9.08 | N/A | 64.55% | CHEMBL236171 | N/A | N/A |
| CBDA | CNR2_HUMAN | cannabinoid receptor 2 | -9.09 | -9.25 | N/A | 70.30% | CHEMBL236171 | N/A | N/A |
| HU-580 | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -3.93 | N/A | N/A | 25.37% | CHEMBL518355 | N/A | N/A |
| CBDA | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -5.57 | N/A | N/A | 26.53% | CHEMBL518355 | N/A | N/A |
| HU-580 | CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.18 | -7.21 | -6.96 | 29.94% | CHEMBL3645131 | Inactive | 64.55% |
| CBDA | CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.48 | -7.00 | -6.74 | 30.82% | CHEMBL3645131 | Inactive | 72.64% |
| HU-580 | CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -7.89 | -7.95 | -7.91 | 33.33% | CHEMBL2205063 | Inactive | 96.64% |
| CBDA | CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -7.98 | -8.28 | -8.05 | 33.57% | CHEMBL2205063 | Inactive | 95.36% |
| HU-580 | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.97 | -6.82 | -7.16 | 31.69% | CHEMBL126657 | N/A | N/A |
| CBDA | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.72 | -7.09 | -6.98 | 32.84% | CHEMBL126657 | N/A | N/A |
| HU-580 | DRD1_HUMAN | dopamine receptor D1 | -7.96 | -8.12 | -8.43 | 46.84% | CHEMBL598730 | Active | 69.20% |
| CBDA | DRD1_HUMAN | dopamine receptor D1 | -8.37 | -8.61 | -7.70 | 44.00% | CHEMBL598915 | Active | 52.03% |
| HU-580 | DRD2_HUMAN | dopamine receptor D2 | -6.94 | N/A | N/A | 47.41% | CHEMBL40634 | N/A | N/A |
| CBDA | DRD2_HUMAN | dopamine receptor D2 | -9.53 | N/A | N/A | 44.00% | CHEMBL598915 | N/A | N/A |
| HU-580 | DRD3_HUMAN | dopamine receptor D3 | -7.62 | N/A | N/A | 48.55% | CHEMBL4082631 | N/A | N/A |
| CBDA | DRD3_HUMAN | dopamine receptor D3 | -7.72 | N/A | N/A | 50.77% | CHEMBL4082631 | N/A | N/A |
| HU-580 | DRD4_HUMAN | dopamine receptor D4 | -8.54 | -8.49 | N/A | 38.57% | CHEMBL1256169 | N/A | N/A |
| CBDA | DRD4_HUMAN | dopamine receptor D4 | -8.04 | -8.05 | N/A | 40.15% | CHEMBL1256169 | N/A | N/A |
| HU-580 | DRD5_HUMAN | dopamine receptor D5 | -9.12 | -9.73 | -7.60 | 46.84% | CHEMBL598730 | Inactive | 52.52% |
| CBDA | DRD5_HUMAN | dopamine receptor D5 | -9.15 | -9.02 | -7.98 | 42.04% | CHEMBL598730 | Active | 70.13% |
| HU-580 | EDNRA_HUMAN | endothelin receptor type A | -7.44 | -7.28 | -7.31 | 38.98% | CHEMBL10847 | Inactive | 58.66% |
| CBDA | EDNRA_HUMAN | endothelin receptor type A | -7.27 | -7.30 | -7.44 | 40.24% | CHEMBL10847 | Inactive | 55.03% |
| HU-580 | GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -1.39 | -2.52 | 4.01 | 19.21% | CHEMBL2391908 | Inactive | 99.99% |
| CBDA | GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -4.24 | -4.28 | 3.71 | 19.53% | CHEMBL2391908 | Inactive | 99.99% |
| HU-580 | GASR_HUMAN | cholecystokinin B receptor | -7.88 | -7.28 | -6.51 | 27.01% | CHEMBL452991 | Inactive | 87.09% |
| CBDA | GASR_HUMAN | cholecystokinin B receptor | -8.00 | -6.84 | -5.81 | 27.12% | CHEMBL286847 | Inactive | 83.32% |
| HU-580 | GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.84 | -8.04 | -6.98 | 32.34% | CHEMBL176068 | Inactive | 69.84% |
| CBDA | GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.83 | -8.59 | -7.42 | 33.33% | CHEMBL176068 | Inactive | 67.89% |
| HU-580 | GRM2_HUMAN | glutamate metabotropic receptor 2 | -2.51 | -0.36 | -2.32 | 47.26% | CHEMBL593013 | Inactive | 99.99% |
| CBDA | GRM2_HUMAN | glutamate metabotropic receptor 2 | -3.90 | -0.83 | -3.00 | 44.06% | CHEMBL593013 | Inactive | 99.99% |
| HU-580 | GRM3_HUMAN | glutamate metabotropic receptor 3 | -5.77 | -7.45 | -8.15 | 35.34% | CHEMBL2112634 | Inactive | 93.46% |
| CBDA | GRM3_HUMAN | glutamate metabotropic receptor 3 | -6.10 | -8.01 | -9.19 | 37.90% | CHEMBL2112634 | Inactive | 95.38% |
| HU-580 | GRM4_HUMAN | glutamate metabotropic receptor 4 | -2.43 | -0.95 | -2.13 | 22.71% | CHEMBL3560239 | Inactive | 99.99% |
| CBDA | GRM4_HUMAN | glutamate metabotropic receptor 4 | -1.74 | -0.62 | -1.38 | 23.63% | CHEMBL3901929 | Inactive | 99.99% |
| HU-580 | GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.33 | -6.11 | -5.72 | 39.13% | CHEMBL1682818 | N/A | N/A |
| CBDA | GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.93 | -6.19 | -5.59 | 36.57% | CHEMBL1682818 | N/A | N/A |
| HU-580 | GRM6_HUMAN | glutamate metabotropic receptor 6 | -5.57 | -6.76 | -6.93 | 19.63% | CHEMBL1585091 | Inactive | 96.17% |
| CBDA | GRM6_HUMAN | glutamate metabotropic receptor 6 | -6.71 | -8.34 | -7.96 | 17.62% | CHEMBL1585091 | Inactive | 98.93% |
| HU-580 | GRM7_HUMAN | glutamate metabotropic receptor 7 | -1.46 | 0.19 | -0.57 | 29.61% | CHEMBL432038 | Inactive | 99.99% |
| CBDA | GRM7_HUMAN | glutamate metabotropic receptor 7 | -1.95 | -3.07 | -1.80 | 30.56% | CHEMBL432038 | Inactive | 99.99% |
| HU-580 | GRM8_HUMAN | glutamate metabotropic receptor 8 | 0.05 | 0.28 | -0.10 | 29.61% | CHEMBL432038 | Inactive | 99.99% |
| CBDA | GRM8_HUMAN | glutamate metabotropic receptor 8 | -0.57 | 0.60 | -1.54 | 30.71% | CHEMBL143210 | Inactive | 99.99% |
| HU-580 | HRH1_HUMAN | histamine receptor H1 | -5.24 | N/A | N/A | 36.23% | CHEMBL1101 | N/A | N/A |
| CBDA | HRH1_HUMAN | histamine receptor H1 | -5.21 | N/A | N/A | 37.69% | CHEMBL1101 | N/A | N/A |
| HU-580 | HRH2_HUMAN | histamine receptor H2 | -8.88 | -8.38 | -8.38 | 32.26% | CHEMBL490632 | Active | 96.87% |
| CBDA | HRH2_HUMAN | histamine receptor H2 | -8.69 | -7.99 | -8.26 | 32.43% | CHEMBL490632 | Active | 97.02% |
| HU-580 | HRH3_HUMAN | histamine receptor H3 | -7.61 | -8.03 | -7.96 | 41.46% | CHEMBL507921 | Inactive | 50.82% |
| CBDA | HRH3_HUMAN | histamine receptor H3 | -7.74 | -8.02 | -8.15 | 39.38% | CHEMBL507921 | Active | 50.14% |
| HU-580 | HRH4_HUMAN | histamine receptor H4 | -7.60 | -7.06 | -7.43 | 33.54% | CHEMBL4063170 | Active | 68.91% |
| CBDA | HRH4_HUMAN | histamine receptor H4 | -9.08 | -7.24 | -9.13 | 34.64% | CHEMBL4063170 | Inactive | 62.20% |
| HU-580 | MC3R_HUMAN | melanocortin 3 receptor | -7.76 | -7.22 | -7.33 | 26.83% | CHEMBL13910 | Inactive | 75.23% |
| CBDA | MC3R_HUMAN | melanocortin 3 receptor | -7.60 | -7.33 | -7.53 | 27.41% | CHEMBL13910 | Inactive | 76.42% |
| HU-580 | MC4R_HUMAN | melanocortin 4 receptor | -7.08 | -7.02 | -6.65 | 32.09% | CHEMBL1490308 | Inactive | 94.88% |
| CBDA | MC4R_HUMAN | melanocortin 4 receptor | -7.27 | -6.30 | -7.33 | 32.31% | CHEMBL1699592 | Inactive | 90.68% |
| HU-580 | MC5R_HUMAN | melanocortin 5 receptor | -6.44 | -7.66 | -5.08 | 25.14% | CHEMBL3913861 | Inactive | 87.57% |
| CBDA | MC5R_HUMAN | melanocortin 5 receptor | -7.27 | -7.36 | -4.44 | 25.75% | CHEMBL3913861 | Inactive | 92.92% |
| HU-580 | MSHR_HUMAN | melanocortin 1 receptor | -8.28 | -8.24 | -8.10 | 26.92% | CHEMBL1682208 | Inactive | 79.86% |
| CBDA | MSHR_HUMAN | melanocortin 1 receptor | -7.96 | -8.19 | -8.69 | 27.41% | CHEMBL13910 | Inactive | 73.05% |
| HU-580 | NK1R_HUMAN | tachykinin receptor 1 | -7.90 | -7.92 | -7.15 | 35.03% | CHEMBL478392 | N/A | N/A |
| CBDA | NK1R_HUMAN | tachykinin receptor 1 | -8.08 | -7.96 | -7.33 | 33.77% | CHEMBL22360 | N/A | N/A |
| HU-580 | NK2R_HUMAN | tachykinin receptor 2 | -7.98 | -8.11 | -8.47 | 30.77% | CHEMBL305660 | Inactive | 98.15% |
| CBDA | NK2R_HUMAN | tachykinin receptor 2 | -8.08 | -8.19 | -8.45 | 29.59% | CHEMBL173420 | Inactive | 98.71% |
| HU-580 | NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.77 | -7.53 | -7.57 | 24.41% | CHEMBL1705448 | Inactive | 94.45% |
| CBDA | NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.20 | -7.36 | -7.31 | 24.88% | CHEMBL1705448 | Inactive | 95.97% |
| HU-580 | NPFF1_HUMAN | neuropeptide FF receptor 1 | -7.46 | -6.95 | -7.28 | 22.70% | CHEMBL2208334 | Inactive | 94.45% |
| CBDA | NPFF1_HUMAN | neuropeptide FF receptor 1 | -7.32 | -7.08 | -7.13 | 23.16% | CHEMBL2208334 | Inactive | 94.42% |
| HU-580 | NPSR1_HUMAN | neuropeptide S receptor 1 | -8.72 | -8.79 | -8.56 | 25.64% | CHEMBL3086828 | Inactive | 61.01% |
| CBDA | NPSR1_HUMAN | neuropeptide S receptor 1 | -8.68 | -8.34 | -8.18 | 27.21% | CHEMBL3086828 | Inactive | 63.64% |
| HU-580 | NPY1R_HUMAN | neuropeptide Y receptor Y1 | -8.85 | -8.77 | -7.92 | 27.52% | CHEMBL556915 | N/A | N/A |
| CBDA | NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.61 | -8.80 | -8.41 | 28.37% | CHEMBL556915 | N/A | N/A |
| HU-580 | NPY2R_HUMAN | neuropeptide Y receptor Y2 | -7.48 | -7.87 | -7.53 | 32.10% | CHEMBL2030193 | Inactive | 97.44% |
| CBDA | NPY2R_HUMAN | neuropeptide Y receptor Y2 | -7.55 | -9.30 | -6.96 | 32.26% | CHEMBL2030193 | Inactive | 84.06% |
| HU-580 | NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.67 | -8.41 | -8.31 | 23.98% | CHEMBL3785576 | Inactive | 76.22% |
| CBDA | NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.88 | -8.33 | -7.89 | 25.31% | CHEMBL3785576 | Inactive | 67.52% |
| HU-580 | NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.11 | -7.51 | -8.18 | 39.88% | CHEMBL469257 | Inactive | 61.66% |
| CBDA | NPY5R_HUMAN | neuropeptide Y receptor Y5 | -7.83 | -7.50 | -7.66 | 41.21% | CHEMBL469257 | Inactive | 82.32% |
| HU-580 | OPRD_HUMAN | opioid receptor delta 1 | -7.15 | -6.96 | -7.23 | 41.43% | CHEMBL160924 | N/A | N/A |
| CBDA | OPRD_HUMAN | opioid receptor delta 1 | -7.09 | -6.76 | -7.18 | 40.88% | CHEMBL571322 | N/A | N/A |
| HU-580 | OPRK_HUMAN | opioid receptor kappa 1 | -8.71 | -7.98 | -7.64 | 42.68% | CHEMBL1773749 | N/A | N/A |
| CBDA | OPRK_HUMAN | opioid receptor kappa 1 | -8.72 | -7.90 | -7.89 | 40.88% | CHEMBL571322 | N/A | N/A |
| HU-580 | OPRM_HUMAN | opioid receptor mu 1 | -7.50 | -6.84 | -7.53 | 44.74% | CHEMBL3948892 | Inactive | 78.56% |
| CBDA | OPRM_HUMAN | opioid receptor mu 1 | -8.46 | -7.22 | -8.85 | 46.53% | CHEMBL3948892 | Inactive | 73.85% |
| HU-580 | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.35 | -7.01 | -7.24 | 36.02% | CHEMBL201805 | N/A | N/A |
| CBDA | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.25 | -7.60 | -7.61 | 34.65% | CHEMBL513585 | N/A | N/A |
| HU-580 | PTAFR_HUMAN | platelet activating factor receptor | -8.37 | -7.80 | -8.40 | 37.04% | CHEMBL297624 | Active | 56.19% |
| CBDA | PTAFR_HUMAN | platelet activating factor receptor | -7.53 | -7.96 | -7.60 | 35.38% | CHEMBL297624 | Inactive | 57.73% |
| HU-580 | TAAR1_HUMAN | trace amine associated receptor 1 | -8.91 | -8.94 | -8.66 | 33.51% | CHEMBL3211097 | Inactive | 52.11% |
| CBDA | TAAR1_HUMAN | trace amine associated receptor 1 | -8.86 | -9.05 | -8.45 | 34.42% | CHEMBL1393484 | Active | 55.93% |
| HU-580 | TSHR_HUMAN | thyroid stimulating hormone receptor | -8.63 | -9.34 | -9.15 | 27.64% | CHEMBL1589735 | Inactive | 97.93% |
| CBDA | TSHR_HUMAN | thyroid stimulating hormone receptor | -8.93 | -9.54 | -9.34 | 25.00% | CHEMBL1589735 | Inactive | 97.87% |
| HU-580 | V1AR_HUMAN | arginine vasopressin receptor 1A | -8.24 | -7.37 | -7.75 | 36.42% | CHEMBL3416859 | Inactive | 76.20% |
| CBDA | V1AR_HUMAN | arginine vasopressin receptor 1A | -8.61 | -7.30 | -8.15 | 35.03% | CHEMBL3416859 | Inactive | 69.24% |
| HU-580 | VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.11 | -8.14 | -8.61 | 22.58% | CHEMBL483749 | N/A | N/A |
| CBDA | VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -7.91 | -8.09 | -8.51 | 22.90% | CHEMBL3884667 | N/A | N/A |