| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -9.30 | -7.64 | -8.20 | 100.00% | CHEMBL2028019 | Active | 99.99% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.67 | -10.10 | -9.10 | 45.69% | CHEMBL370128 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.15 | -9.41 | -8.54 | 72.16% | CHEMBL1085672 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.48 | -8.91 | -9.30 | 31.52% | CHEMBL29410 | Inactive | 66.40% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -8.71 | -9.47 | -9.32 | 36.81% | CHEMBL186951 | Active | 54.14% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -10.04 | -9.64 | N/A | 100.00% | CHEMBL2028019 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.84 | -9.93 | -9.37 | 60.00% | CHEMBL209254 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -9.08 | -9.70 | N/A | 60.00% | CHEMBL209254 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -10.38 | -9.37 | -9.36 | 37.41% | CHEMBL539651 | Active | 52.02% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -9.43 | -8.58 | -9.18 | 46.73% | CHEMBL3764335 | Active | 50.86% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -9.01 | -9.38 | -8.45 | 77.78% | CHEMBL4639203 | Active | 98.92% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -9.48 | -9.70 | -8.67 | 100.00% | CHEMBL2028019 | Active | 99.99% |
| AA1R_HUMAN | adenosine A1 receptor | -8.28 | -9.08 | -7.96 | 30.43% | CHEMBL329774 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -8.95 | -9.25 | -8.59 | 34.23% | CHEMBL539454 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.65 | -9.98 | -8.50 | 32.61% | CHEMBL4441276 | Inactive | 53.95% |
| AA3R_HUMAN | adenosine A3 receptor | -2.82 | -1.89 | -6.67 | 30.98% | CHEMBL4460114 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.57 | 6.28 | N/A | 70.79% | CHEMBL256202 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.52 | -8.74 | -6.13 | 44.74% | CHEMBL310132 | Active | 68.29% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -9.24 | -10.06 | -9.62 | 49.52% | CHEMBL1094003 | Active | 65.06% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.16 | -7.79 | N/A | 38.02% | CHEMBL728 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -9.70 | -10.42 | -9.29 | 43.80% | CHEMBL1090094 | Active | 78.77% |
| ACTHR_HUMAN | melanocortin 2 receptor | -9.43 | -9.60 | -7.70 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -9.01 | -8.31 | -9.13 | 73.91% | CHEMBL56438 | Active | 86.03% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | 2.98 | 4.62 | 4.61 | 45.61% | CHEMBL1221593 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -9.67 | -8.11 | -7.17 | 40.38% | CHEMBL51358 | Active | 62.86% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 2.50 | 6.87 | 10.71 | 42.96% | CHEMBL1112 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.70 | -9.73 | -9.26 | 61.54% | CHEMBL1424807 | Active | 86.61% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -8.20 | -8.89 | -9.26 | 54.95% | CHEMBL417709 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -9.87 | -10.24 | -9.72 | 39.45% | CHEMBL155072 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -8.86 | -9.19 | -8.81 | 38.21% | CHEMBL290829 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -10.03 | -10.08 | -10.06 | 52.25% | CHEMBL110652 | Active | 89.32% |
| CALCR_HUMAN | calcitonin receptor | -8.18 | -8.25 | -8.39 | 30.95% | CHEMBL4462020 | Inactive | 98.39% |
| CCKAR_HUMAN | cholecystokinin A receptor | -7.99 | -7.97 | -8.63 | 45.74% | CHEMBL357983 | Inactive | 88.31% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.25 | -8.71 | -8.22 | 61.70% | CHEMBL2398758 | Active | 53.64% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.48 | -9.05 | -8.31 | 57.84% | CHEMBL2036748 | Active | 88.79% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.72 | -7.85 | -9.10 | 38.31% | CHEMBL600805 | Inactive | 61.18% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.13 | -7.93 | -8.62 | 53.51% | CHEMBL3398002 | Inactive | 80.89% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.87 | -9.62 | -9.28 | 23.28% | CHEMBL3342954 | Inactive | 83.33% |
| CNR1_HUMAN | cannabinoid receptor 1 | -8.78 | -9.12 | -10.19 | 59.26% | CHEMBL3799603 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -9.12 | -9.85 | N/A | 51.00% | CHEMBL2338177 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | 3.16 | N/A | N/A | 28.26% | CHEMBL386072 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.44 | -7.62 | -7.76 | 40.29% | CHEMBL4103634 | Inactive | 60.81% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -9.12 | -9.58 | -8.50 | 52.17% | CHEMBL583655 | Inactive | 59.64% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.74 | -7.04 | -8.07 | 37.62% | CHEMBL2347625 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.12 | -8.91 | -9.99 | 51.49% | CHEMBL1940408 | Active | 70.83% |
| DRD2_HUMAN | dopamine receptor D2 | -8.83 | N/A | N/A | 100.00% | CHEMBL2028019 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.72 | N/A | N/A | 100.00% | CHEMBL2028019 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -9.72 | -9.59 | N/A | 100.00% | CHEMBL2028019 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -8.55 | -10.46 | -8.98 | 45.00% | CHEMBL238718 | Active | 69.46% |
| EDNRA_HUMAN | endothelin receptor type A | -7.71 | -8.05 | -7.17 | 33.96% | CHEMBL170121 | Active | 57.36% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 13.56 | 0.63 | 22.57 | 19.33% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.69 | -8.13 | -7.32 | 54.84% | CHEMBL317108 | Active | 59.21% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -9.05 | -10.06 | -8.29 | 49.52% | CHEMBL2397378 | Active | 57.51% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | 5.71 | 5.01 | 4.95 | 41.60% | CHEMBL1097052 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -2.89 | -3.42 | -6.94 | 30.83% | CHEMBL4447269 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 5.07 | 6.85 | 10.53 | 51.04% | CHEMBL578358 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -8.68 | -5.83 | -7.14 | 45.79% | CHEMBL1688366 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -1.47 | -5.01 | -0.91 | 41.74% | CHEMBL2418359 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -3.19 | 0.54 | -2.26 | 38.89% | CHEMBL4575681 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 5.35 | 3.29 | 7.88 | 41.74% | CHEMBL2418359 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -8.84 | N/A | N/A | 47.75% | CHEMBL476935 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -10.54 | -9.85 | -9.74 | 36.81% | CHEMBL4562437 | Active | 98.75% |
| HRH3_HUMAN | histamine receptor H3 | -8.17 | -8.94 | -8.94 | 75.29% | CHEMBL489590 | Active | 98.43% |
| HRH4_HUMAN | histamine receptor H4 | -9.13 | -8.37 | -8.88 | 53.27% | CHEMBL1223683 | Active | 79.26% |
| MC3R_HUMAN | melanocortin 3 receptor | -9.21 | -8.87 | -8.08 | 44.26% | CHEMBL1762009 | Inactive | 52.03% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.27 | -7.25 | -7.62 | 49.22% | CHEMBL197278 | Inactive | 60.69% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.66 | -8.44 | -5.02 | 44.26% | CHEMBL1762009 | Inactive | 67.75% |
| MSHR_HUMAN | melanocortin 1 receptor | -8.25 | -7.41 | -7.96 | 44.26% | CHEMBL1762009 | Inactive | 65.22% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.96 | -8.78 | -8.85 | 55.17% | CHEMBL345866 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -9.13 | -9.21 | -9.00 | 44.53% | CHEMBL3651891 | Inactive | 81.62% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -8.89 | -8.51 | -8.15 | 33.91% | CHEMBL1940354 | Inactive | 84.10% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.83 | -8.12 | -8.31 | 52.89% | CHEMBL3361421 | Active | 59.19% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -8.94 | -9.53 | -8.71 | 31.94% | CHEMBL1210177 | Inactive | 59.18% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -10.18 | -9.23 | -9.45 | 47.17% | CHEMBL2046860 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -7.90 | -8.46 | -8.16 | 60.00% | CHEMBL560914 | Inactive | 59.35% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.58 | -9.14 | -8.70 | 35.38% | CHEMBL4456247 | Inactive | 94.82% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -9.15 | -8.73 | -8.81 | 51.85% | CHEMBL255352 | Active | 73.80% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.82 | -6.87 | -8.26 | 46.40% | CHEMBL401451 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.60 | -8.65 | -9.09 | 69.23% | CHEMBL254154 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.80 | -8.64 | -7.77 | 51.40% | CHEMBL240001 | Inactive | 56.35% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.28 | -7.89 | -8.03 | 55.96% | CHEMBL1762372 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.37 | -8.32 | -8.97 | 28.57% | CHEMBL345902 | Inactive | 70.49% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -9.40 | -9.70 | -9.10 | 41.18% | CHEMBL1391385 | Inactive | 75.79% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -10.35 | -10.52 | -10.22 | 34.59% | CHEMBL3911383 | Inactive | 67.20% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -8.31 | -8.52 | -8.98 | 43.80% | CHEMBL318392 | Inactive | 62.30% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.09 | -7.86 | -8.30 | 26.70% | CHEMBL4284839 | N/A | N/A |